Psychopathology assessed across the lifespan often can be summarized with a few broad dimensions: internalizing, externalizing, and psychosis/thought disorder. Extensive overlap between internalizing and externalizing symptoms has garnered interest in bifactor models comprised of a general co-occurring factor and specific internalizing and externalizing factors. We focus on internalizing and externalizing symptoms and compare a bifactor model to a correlated two-factor model of psychopathology at three timepoints in a large adolescent community sample (N = 387; 55 % female; 83% Caucasian; M age = 12.1 at wave 1) using self- and parent-reports. Each model was tested within each time-point with 25–28 validators. The bifactor models demonstrated better fit to the data. Child report had stronger invariance across time. Parent report had stronger reliability over time. Cross-informant correlations between the factors at each wave indicated that the bifactor model had slightly poorer convergent validity but stronger discriminant validity than the two-factor model. With notable exceptions, this pattern of results replicated across informants and waves. The overlap between internalizing and externalizing pathology is systematically and, sometimes, non-linearly related to risk factors and maladaptive outcomes. Strengths and weaknesses to modeling psychopathology as two or three factors and clinical and developmental design implications are discussed.

This article seeks to understand the evolving democratic legitimacy demands of the United Nations Framework Convention on Climate Change (UNFCCC) by reflecting on the challenges of catering to a globally affected public and enhanced participation opportunities given to some highly affected groups. It argues that the principle of democratic equality at a global scale fails to take account of inequities in affectedness and power within the demos and, instead, an approach that strives towards a principle of proportionality based on degrees of affectedness could enhance the UNFCCC’s democratic legitimacy. This builds on existing scholarship identifying a turn to an affectedness paradigm in international institutions more generally and the emerging influence of affected peoples organisations, characterised by the more direct forms of representation they facilitate and emphasis placed on the affectedness of their constituents to claim recognition and influence. The normative appeal of giving enhanced participatory opportunities to those most affected by climate governance is weighed against its challenges and risks. It is concluded that, despite conceptual and practical difficulties connected to the subjective nature of affectedness, a pragmatic approach that treats such a proportionality principle as a democratic ideal to be strived towards could have a legitimising effect on the UNFCCC.

Menarche and pubertal onset vary across populations but understanding age-at-menarche (AAM) and pubertal growth tempo is limited in low-income settings. Identifying factors influencing pubertal development is vital for creating targeted health and education programmes supporting adolescent girls’ well-being. Baseline data (n = 1045) from the Ten2Twenty-Ghana study were analysed to examine menarche attainment, pubertal development, AAM, and the associated factors among girls aged 10-17 years in the Mion district, Ghana. The data collection methods included anthropometry, body composition, haemoglobin status, a qualitative 24-hour dietary recall, a food frequency questionnaire, and a pubertal development score (PDS). Binary logistic and linear regression analyses were used to model odds ratios for menarche attainment and regression coefficients for AAM and PDS. About 19.9% of the girls had experienced menarche, with a mean AAM of 13.4 ± 1.5 years. Among post-menarche girls (n = 205/1045), 12.2% and 15.1% experienced early (AAM < 12 years) and late menarche (AAM < 15 years), respectively. The mean PDS was 1.8 ± 0.7 out of 4. Among the adolescent girls, 36.2% were prepubertal, 17.0% early –pubertal, 18.6% mid-pubertal, 27.9% late pubertal, and less than 1% were in the post-pubertal stage. An increase in fat mass (FM), fat-free mass (FFM), height-for-age-z-score (HAZ), and body mass index-for-age-z-score (BAZ) was observed with puberty progression, but a steep decline in HAZ was noticed for girls in late puberty, increasing again post-puberty. Being older (adjusted odds ratio (AOR) = 2.06, 95% C.I.: 1.83, 2.31), stunted (AOR= 0.20, 95% C.I.: 0.10, 0.40), thin (AOR = 0.30, 95% C.I.: 0.11, 0.80), and overweight/obese (AOR = 7.29, 95% C.I.: 2.60, 20.43) were the significant predictors of menarche attainment. Being older (β = 0.39, P < 0.0001), stunted (β= -0.92, P = 0.01), thin (β = 1.25, P = 0.01), and having a literate mother (β = -0.72, P = 0.03) were significantly associated with AMM. A higher HAZ, FM, FFM, age, and Konkomba ethnicity were positively associated with higher PDS. This study highlights the complexity of factors influencing menarche and pubertal development. These insights are essential for developing targeted health and educational programmes that address nutritional and socio-demographic disparities to promote adolescent girls’ well-being and healthy pubertal development.

The effect of reservoir construction on medically important parasites is well known worldwide but lacks information in Vietnam. With 385 active hydropower plants and numerous water reservoirs, Vietnam provides an ideal setting for studying this issue. This study investigated trematode infection in snail first intermediate hosts from three hydropower reservoirs: Hoa Binh, Son La, and Thac Ba. In total, 25,299 snails representing 16 species were examined, with 959 individuals (8 species) shedding identifiable cercariae. Infection prevalence was highest in thiarid snails (5.4%–15.4%), followed by bithynid snails (2.9%–5.8%). Other snail species showed infection prevalence ranging from 0.3% to 2.9%. Infection prevalence varied significantly across regions, with the highest prevalence in Son La, followed by Hoa Binh and Thac Ba reservoirs. However, no significant differences were observed between snails collected from reservoirs versus canals and paddy fields. Morphological identification resulted in nine cercarial morphotypes, with pleurolophocercaria, xiphidiocercariae, and echinostome being the most common types, accounting for 89.2% of all cercarial infections. Echinostome cercariae were found in seven snail species, while the other cercarial morphotypes were shed by two to five species. Gabbia fuchsiana, Parafossarulus manchouricus, and Melanoides tuberculata were the most common hosts, each harboring five cercarial morphotypes, while Radix auricularia only released echinostome type. In conclusion, our findings highlight the endemic presence of trematodes in hydropower reservoirs and emphasize the need to consider the human-environment interaction around these reservoirs for a better understanding of disease transmission risks.

Imagine being in a university that functions in a place-based culturally regenerative way. In this concept paper, the authors bring together theory, practice, and experience, in the service of transforming universities towards place-based cultural regeneration. At present, Australian universities operate using an economic philosophy of neoliberal corporatism characterised by hierarchical management strategies, competitive tendencies, patriarchal values, and discourse characterised by bifurcation or binary thinking. These features illustrate a worldview that is entangled with the meta crises of our times such as climate change, species loss, hatred/intolerance, and unfathomable violence. The authors consider ways of moving towards a place-based, Indigenous-informed, practical, relational way of learning, being and knowing differently. The paper tentatively assembles a local, place-based culturally regenerative worldview based on living, vibrant, responsive places that embrace people who collaborate with Country – in the Indigenous sense of deep relationality. Within this worldview, the authors propose collaborative ways of governing, teaching, learning, and leading that is necessary for place-based cultural regeneration. In conclusion, the authors outline a pathway towards universities as places of regenerative cultures, which prioritise the nurturing of learning to live and work beyond the current societal paralysis on the road to collapse.

This work focuses on the study of three pelagic fish species of the same genus, caught from the south-western coasts of the Mediterranean. It concerns lipid content, fatty acid profile and nutritional quality (atherogenic index, thrombogenicity index, ratio between hypocholesterolemic and hypercholesterolemic fatty acids and n6-to-n3 ratio) of Trachurus trachurus, Trachurus mediterraneus and Trachurus picturatus. Lipid extraction and esterification were carried out on the flesh of each species, and fatty acid methyl esters were analysed using gas chromatography-mass spectrometry. The obtained results show that lipid content mean values vary between 2.87 and 5.06%, saturated fatty acids contents range from 37.51 to 53.23%, monounsaturated fatty acids content range from 29.24 to 37.65% and polyunsaturated fatty acids content range from 9.11 to 33.24% according to species. Also, the different mean values of indexes describing the nutritional quality vary significantly depending on species. That confirms the good quality of studied species and their importance for human nutrition and health, hence the urgent need to preserve their stocks.

This study investigated the co-infection dynamics of Schistosoma mansoni and Ancylostoma ceylanicum in an experimental model. Two experiments were conducted to investigate varying infection orders. In experimental group 1, subjects were initially infected with A. ceylanicum, followed by S. mansoni infection. In group 2, subjects were first infected with S. mansoni, followed by A. ceylanicum infection. The co-infected groups were compared to mono-infected groups for further analysis. Parameters assessed included weight, fecal egg elimination, blood cell counts, IgG response, histopathological analysis, and granuloma morphometry. Results indicated that the timing of infections influenced weight loss. Co-infected animals lost weight similarly to A. ceylanicum-infected animals when A. ceylanicum preceded S. mansoni. The co-infected groups did not experience worsened anemia, despite both parasites being hematophagous. No linear correlation was found between S. mansoni egg counts and anti-SEA IgG production. The response to the S. mansoni adult worm antigen was significantly higher in the S. mansoni mono-infected group compared to the group previously infected with hookworm. Co-infection with A. ceylanicum after S. mansoni infection also interfered with the host response. It caused a delay in the peak of S. mansoni egg elimination compared to the S. mansoni monoinfected group. Additionally, fewer eggs were retained in the liver compared to single infections. These findings help elucidate the interactions between different parasites and their hosts in the same endemic area, providing valuable information to enhance strategies for disease control and management.

Digital twins are a new paradigm for our time, offering the possibility of interconnected virtual representations of the real world. The concept is very versatile and has been adopted by multiple communities of practice, policymakers, researchers, and innovators. A significant part of the digital twin paradigm is about interconnecting digital objects, many of which have previously not been combined. As a result, members of the newly forming digital twin community are often talking at cross-purposes, based on different starting points, assumptions, and cultural practices. These differences are due to the philosophical world-view adopted within specific communities. In this paper, we explore the philosophical context which underpins the digital twin concept. We offer the building blocks for a philosophical framework for digital twins, consisting of 21 principles that are intended to help facilitate their further development. Specifically, we argue that the philosophy of digital twins is fundamentally holistic and emergentist. We further argue that in order to enable emergent behaviors, digital twins should be designed to reconstruct the behavior of a physical twin by “dynamically assembling” multiple digital “components”. We also argue that digital twins naturally include aspects relating to the philosophy of artificial intelligence, including learning and exploitation of knowledge. We discuss the following four questions (i) What is the distinction between a model and a digital twin? (ii) What previously unseen results can we expect from a digital twin? (iii) How can emergent behaviours be predicted? (iv) How can we assess the existence and uniqueness of digital twin outputs?

What determines the legitimacy of aspiring rulers? Questions about support of the governed are central to theories of state-building and political order. Millions worldwide live under the influence of competing armed groups, yet we know little about how people in these contexts make comparative assessments of would-be rulers. We theorize how local norms, social networks, and the provision of goods and services influence these comparative judgments. We report results from a conjoint survey experiment in Colombia among nearly 2,400 respondents across 54 municipalities contested by multiple armed groups. Armed groups that take community norms into account and those that involve local leaders in decision-making are judged less negatively. Additionally, providing services and limiting violence both reduce negative evaluations of armed groups. These findings help us understand dimensions of political legitimacy under limited statehood and the effects of governance on civilian attitudes in areas of competition.

Ulakhan Sular provides one of the largest natural stratigraphic sections through ancient permafrost deposits in the Batagay–Betenkes region of the Yana Uplands of western Beringia, but their depositional environment, age, and paleoenvironmental significance are uncertain. To address these uncertainties, we report the results of reconnaissance observations of the stratigraphy, sedimentology, paleosols and soil-like bodies, plant and insect macrofossils, and geochronology of the permafrost deposits at the stratotype section of the Ulakhan Sular Formation. Sedimentologically, this formation is dominated by well-sorted, fine to very fine sand that contains fluvial, aeolian, and permafrost sedimentary structures consistent with deposition near the paleo-Adycha River. The fluvio-aeolian deposits have similarities and differences to periglacial fluvio-aeolian and aeolian deposits in modern arctic regions of Canada and Greenland, and Pleistocene deposits in Alaska, China, and northwest Europe. The remarkable thickness of aeolian deposits (~50 m) at Ulakhan Sular is attributed to abundant local sand sources, ample accommodation space, and intensive aeolian transport and deposition. Optically stimulated luminescence dating of quartz sand and post-infrared–infrared dating of K-feldspar sand suggests deposition of the Ulakhan Sular Formation during late Marine Oxygen Isotope Stage (MIS) 6 or MIS 5. The aeolian sand-sheet deposits are correlated with other cold-climate aeolian sand and silt (loess) deposits in Beringia and southern Siberia, indicating a regional episode of aeolian sand transport and deposition at a similar time to glaciation by the Eastern Siberian Ice Sheet.

Earth System Science stands as the future operating framework to monitor the pulse of the Earth, and to diagnose and address the challenges of global change. Magmatism and volcanism are primary processes connecting the solid Earth to the atmosphere, hydrosphere, and biosphere. In addition to regulating the Earth system, they are both an unavoidable source of hazards and a tremendous resource of energy and raw materials. Accessing magma is the necessary next step in the exploration of our planet. It will enable us to develop next-generation geothermal energy (magma energy), to transform volcano monitoring strategies, and perhaps even to alleviate volcanic activity. Recent exploratory geothermal drilling activities around the world have serendipitously encountered shallow magma bodies in the Earth. Following these remarkable magma drilling occurrences, the Krafla Magma Testbed (KMT) has been established in Iceland in order to create the first magma observatory – a world-class international in situ magma laboratory with access to the magma-rock-hydrothermal boundary through wells suitable for advanced studies and experiments. Here we review the importance of magma in the Earth system, present the multifaceted need for magma observatories and introduce the benefits of KMT as we enter a new generation of energy demands and resilience strategies.

Most scholars agree that candidates’ use of negative campaigning is based on rational considerations, i.e., weighing likely benefits against potential costs. We argue that this perspective is far too narrow and outline the elements of a comprehensive model on the use of negative campaign communication that builds on personality traits, values, social norms, and attitudes toward negative campaigning as complementary mechanisms to classical rational choice theory. We test our theoretical assumptions using candidate surveys for twelve state elections in Germany with more than 3,100 candidates. Our results strongly suggest that negative campaigning goes beyond rational considerations. Although benefit–cost calculations are the primary driver of the decision to attack the opponent, other factors are also important and enhance our understanding of why candidates choose to engage in negative campaign communication. Our findings have important implications for research on candidate attack behavior.

The humanities cannot go public without publishing. In this contribution to the Manifesto issue of Public Humanities, Daniel Fisher-Livne, Kath Burton, and Catherine Cocks highlight the radically inclusive publishing practices necessary to support the Public Humanities ecosystem. The authors explain how Publishing and the Publicly Engaged Humanities Working Group activities have prepared the ground for future growth, directing attention to the inherently collaborative, multimodal and values-based publishing practices of engaged scholars. This paper builds on the central thesis of the Working Group, calling for the implementation of a radically inclusive ecology of publishing practices that embody and nurture the unique facets, connections and aims of publicly engaged publications.

As Chile embarked on a constitutional replacement process during its worst-ever drought, local environmental activists secured significant representation at the Constitutional Convention responsible for drafting a new constitution, and successfully integrated provisions on climate change and water protection. However, despite the popularity of these measures, the citizenry rejected the proposal. This article, using legal mobilization and constitutional reform studies, examines the dynamics of constitutional mobilization against climate change, presenting two major findings. First, the feasibility of constitutional mobilization hinges on the ability of activists to navigate the politics of constitutional change, as their tactical choices are crucial for enhancing the process’s legitimacy. Second, including environmental measures in a constitutional replacement process tie them to less popular provisions, potentially jeopardizing the entire process, delaying state action on climate change, and weakening activists’ standing. The data supporting these findings come from interviews with Constitutional Convention delegates, archival research, and participant observation. In a context where climate change is intensifying, this article underscores the unintended consequences and challenges of pursuing environmental goals through constitutional reforms.

We use deformations and mutations of scattering diagrams to show that a scattering diagram with initial functions $f_1=(1+tx)^\mu $ and $f_2=(1+ty)^\nu $ has a dense region. This answers a question asked by Gross and Pandharipande [‘Quivers, curves, and the tropical vertex’, Port. Math. 67(2) (2010), 211–259] which had been proved only for the case $\mu =\nu $.

The present study described and illustrated the larval morphology of the three first zoeal stages (zoea I–III) of Synalpheus fritzmuelleri and compared with the previous described larvae of this species. The results pointed out a variety of differences among the descriptions, most of them related to the type and number of setae and articulation of appendages. The first zoea demonstrates similarities shared with the zoea I within the genus besides the diagnostic described characteristics. Other incongruences were also found such as the lack of information about some structures, such as the maxillule in the zoea I, and the use of ambiguous terms do designate type of setae. Moreover, the more advanced the zoea, additional differences were found among the previous and the current descriptions. Due to that, the necessity to review and also add new descriptions for Synalpheus larvae proves imminent to establish a standardization in the morphological description that will strengthen the comparative relationship in the genus.

This article establishes a data-driven modeling framework for lean hydrogen ($ {\mathrm{H}}_2 $)-air reaction rates for the Large Eddy Simulation (LES) of turbulent reactive flows. This is particularly challenging since $ {\mathrm{H}}_2 $ molecules diffuse much faster than heat, leading to large variations in burning rates, thermodiffusive instabilities at the subfilter scale, and complex turbulence-chemistry interactions. Our data-driven approach leverages a Convolutional Neural Network (CNN), trained to approximate filtered burning rates from emulated LES data. First, five different lean premixed turbulent $ {\mathrm{H}}_2 $-air flame Direct Numerical Simulations (DNSs) are computed each with a unique global equivalence ratio. Second, DNS snapshots are filtered and downsampled to emulate LES data. Third, a CNN is trained to approximate the filtered burning rates as a function of LES scalar quantities: progress variable, local equivalence ratio, and flame thickening due to filtering. Finally, the performances of the CNN model are assessed on test solutions never seen during training. The model retrieves burning rates with very high accuracy. It is also tested on two filter and downsampling parameters and two global equivalence ratios between those used during training. For these interpolation cases, the model approximates burning rates with low error even though the cases were not included in the training dataset. This a priori study shows that the proposed data-driven machine learning framework is able to address the challenge of modeling lean premixed $ {\mathrm{H}}_2 $-air burning rates. It paves the way for a new modeling paradigm for the simulation of carbon-free hydrogen combustion systems.

We prove two sharp anisotropic weighted geometric inequalities that hold for star-shaped and F-mean convex hypersurfaces in $\mathbb{R}^{n+1}$, which involve the anisotropic p-momentum, the anisotropic perimeter, and the volume of the region enclosed by the hypersurface. We also consider their quantitative versions characterized by asymmetry index and the Hausdorff distance between the hypersurface and a rescaled Wulff shape. As a corollary, we obtain the stability of the Weinstock inequality for the first non-zero Steklov eigenvalue for star-shaped and strictly mean convex domains.