Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-25T13:34:22.640Z Has data issue: false hasContentIssue false
  • English
  • Français

Parental brain and socioeconomic epigenetic effects in human development

Published online by Cambridge University Press:  24 October 2012

James E. Swain ,
Suzanne C. Perkins ,
Carolyn J. Dayton ,
Eric D. Finegood  and
S. Shaun Ho
James E. Swain
Affiliation:
Department of Psychiatry, University of Michigan School of Medicine, Ann Arbor, MI 48109. [email protected]://www2.med.umich.edu/psychiatry/psy/fac_query4.cfm?link_name=jamesswasperkinz@[email protected]@[email protected]
Suzanne C. Perkins
Affiliation:
Department of Psychiatry, University of Michigan School of Medicine, Ann Arbor, MI 48109. [email protected]://www2.med.umich.edu/psychiatry/psy/fac_query4.cfm?link_name=jamesswasperkinz@[email protected]@[email protected]
Carolyn J. Dayton
Affiliation:
Department of Psychiatry, University of Michigan School of Medicine, Ann Arbor, MI 48109. [email protected]://www2.med.umich.edu/psychiatry/psy/fac_query4.cfm?link_name=jamesswasperkinz@[email protected]@[email protected]
Eric D. Finegood
Affiliation:
Department of Psychiatry, University of Michigan School of Medicine, Ann Arbor, MI 48109. [email protected]://www2.med.umich.edu/psychiatry/psy/fac_query4.cfm?link_name=jamesswasperkinz@[email protected]@[email protected]
S. Shaun Ho
Affiliation:
Department of Psychiatry, University of Michigan School of Medicine, Ann Arbor, MI 48109. [email protected]://www2.med.umich.edu/psychiatry/psy/fac_query4.cfm?link_name=jamesswasperkinz@[email protected]@[email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Critically significant parental effects in behavioral genetics may be partly understood as a consequence of maternal brain structure and function of caregiving systems recently studied in humans as well as rodents. Key parental brain areas regulate emotions, motivation/reward, and decision making, as well as more complex social-cognitive circuits. Additional key environmental factors must include socioeconomic status and paternal brain physiology. These have implications for developmental and evolutionary biology as well as public policy.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 35 , Issue 5 , October 2012 , pp. 378 - 379
Copyright
Copyright © Cambridge University Press 2012 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barclay, L., Everitt, L., Rogan, F., Schmied, V. & Wyllie, A. (1997) Becoming a mother – an analysis of women's experience of early motherhood. Journal of Advanced Nursing 25(4):719–28.Google Scholar
Barrett, J. & Fleming, A. S. (2011) Annual Research Review: All mothers are not created equal: Neural and psychobiological perspectives on mothering and the importance of individual differences. Journal of Child Psychology and Psychiatry 52(4):368–97.CrossRefGoogle Scholar
Bowlby, J. (1978) Attachment theory and its therapeutic implications. Adolescent Psychiatry 6:5–33.Google Scholar
Brown, S. L., Brown, R. M. & Preston, S. (2012) The human caregiving system: A neuroscience model of compassionate motivation and behavior. In: Moving beyond self interest: Perspectives from evolutionary biology, neuroscience, and the social sciences, ed. Brown, S. L., Brown, R. M. & Penner, L., pp. 89–108. Oxford University Press.Google Scholar
Buss, C., Lord, C., Wadiwalla, M., Hellhammer, D. H., Lupien, S. J., Meaney, M. J. & Pruessner, J. C. (2007) Maternal care modulates the relationship between prenatal risk and hippocampal volume in women but not in men. Journal of Neuroscience 27(10):2592–95.Google Scholar
Cassidy, J. & Shaver, P. R. (1999) Handbook of attachment. Guilford Press.Google Scholar
Champagne, F. A. (2010b) Epigenetic influence of social experiences across the lifespan. Developmental Psychobiology 52(4):299–311.Google Scholar
Chong, S., Vickaryous, N., Ashe, A., Zamudio, N., Youngson, N., Hemley, S., Stopka, T., Skoultchi, A., Mathews, J., Scott, H.S., de Kretser, D., O'Bryan, M., Blewitt, M., Whitelaw, E. (2007) Modifiers of epigenetic reprogramming show paternal effects in the mouse. Nature Genetics 39(5):614–22.Google Scholar
Conger, R. D. & Donnellan, M. B. (2007) An interactionist perspective on the socioeconomic context of human development. Annual Review of Psychology 58 175–99.CrossRefGoogle ScholarPubMed
Dawson, G., Ashman, S. B. & Carver, L. J. (2000) The role of early experience in shaping behavioral and brain development and its implications for social policy. Developmental Psychopathology 12(4):695–712.Google Scholar
Dietz, D. M., Laplant, Q., Watts, E. L., Hodes, G. E., Russo, S. J., Feng, J., Oosting, R. S., Vialou, V., Nestler, E. J. (2011) Paternal transmission of stress-induced pathologies. Biological Psychiatry 70(5):408–14.Google Scholar
Dietz, D. M. & Nestler, E. J. (2012) From father to offspring: Paternal transmission of depressive-like behaviors. Neuropsychopharmacology 37(1):311–12.Google Scholar
Evans, G. W. (2003) A multimethodological analysis of cumulative risk and allostatic load among rural children. Developmental Psychology 39(5):924–33.Google Scholar
Feldman, R. (2007) Parent–infant synchrony and the construction of shared timing; Physiological precursors, developmental outcomes, and risk conditions. Journal of Child Psychology and Psychiatry 48(3–4):329–54.Google Scholar
Francis, D. D., Diorio, J., Liu, D. & Meaney, M. J. (1999) Nongenomic transmission across generations of maternal behavior and stress responses in the rat. Science, 286(5442):1155–58.Google Scholar
Gianaros, P. J., Horenstein, J. A., Cohen, S., Matthews, K. A., Brown, S. M., Flory, J. D., Critchley, H. D., Manuck, S. B. & Hariri, A. R. (2007) Perigenual anterior cingulate morphology covaries with perceived social standing. Social Cognition & Affective Neuroscience 2(3):161–73.Google Scholar
Gianaros, P. J., Horenstein, J. A., Hariri, A. R., Sheu, L. K., Manuck, S. B., Matthews, K. A. & Cohem, S. (2008) Potential neural embedding of parental social standing. Social Cognition & Affective Neuroscience 3(2):91–96.Google Scholar
Goodman, J. H. (2002) Becoming an involved father of an infant. Journal of Obstetric Gynecologic & Neonatal Nursing 34(2):190–200.Google Scholar
Hackman, D. A., Farah, M. J. & Meaney, M. J. (2010) Socioeconomic status and the brain: Mechanistic insights from human and animal research. Nature Reviews Neuroscience 11(9):651–59.Google Scholar
Kim, P., Leckman, J. F., Mayes, L. C., Feldman, R., Wang, X. & Swain, J. E. (2010a) The plasticity of human maternal brain: Longitudinal changes in brain anatomy during the early postpartum period. Behavioral Neuroscience 124(5):695–700.Google Scholar
Kim, P., Leckman, J. F., Mayes, L. C., Newman, M. A., Feldman, R. & Swain, J. E. (2010b) Perceived quality of maternal care in childhood and structure and function of mothers' brain. Developmental Science 13(4):662–73.Google Scholar
Korosi, A. & Baram, T. Z. (2010) Plasticity of the stress response early in life: Mechanisms and significance. Developmental Psychobiology 52(7):661–70.Google Scholar
McEwen, B. S. & Gianaros, P. J. (2010) Central role of the brain in stress and adaptation: Links to socioeconomic status, health, and disease. Annals of the New York Academy of Sciences 1186:190–222.Google Scholar
McLoyd, V. C. (1998) Socioeconomic disadvantage and child development. American Psychology 53(2):185–204.Google Scholar
Meaney, M. J. (2001) Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annual Review of Neuroscience 24:1161–92.Google Scholar
Mercer, R. T. (1985) The process of maternal role attainment over the first year. Nursery Research 34(4):198–204.Google Scholar
Muscatell, K. A., Morelli, S. A., Falk, E. B., Way, B. M., Pfeifer, J. H., Galinsky, A. D., Lieberman, M. D., Dapretto, M. & Eisenberger, N.I. (2012) Social status modulates neural activity in the mentalizing network. NeuroImage 60(3):1771–77.Google Scholar
NICHD Early Care Research Network (2006) Infant–mother attachment classification: Risk and protection in relation to changing maternal caregiving quality. Developmental Psychology 42(1):38–58.Google Scholar
Swain, J. E. (2011) The human parental brain: In vivo neuroimaging. Progress in Neuro-Psychopharmacology and Biological Psychiatry 35(5):1242–54.Google Scholar
Swain, J. E., Konrath, S., Brown, S., Finegood, E., L., B.-A. & Ho, S. S. (2012) Parenting and beyond: Common neurocircuits underlying parental and altruistic caregiving. Parenting, Science and Practice 12:115–123.Google Scholar
Swain, J. E., Leckman, J. F., Mayes, L. C., Feldman, R., Hoyt, E., Kang, H., Kim, P., Constable, R. T. & Schultz, R. T. (under review) Functional brain activations of parents listening to their own baby-cry change over the early postpartum. Developmental Psychobiology.Google Scholar
Taylor, S. E., Eisenberger, N. I., Saxbe, D., Lehman, B. J. & Lieberman, M. D. (2006) Neural responses to emotional stimuli are associated with childhood family stress. Biological Psychiatry 60(3):296–301.Google Scholar
Tomoda, A., Suzuki, H., Rabi, K., Sheu, Y. S., Polcari, A. & Teicher, M. H. (2009) Reduced prefrontal cortical gray matter volume in young adults exposed to harsh corporal punishment. NeuroImage 47(Suppl 2):T66–71.Google Scholar
Woon, F. L. & Hedges, D. W. (2008) Hippocampal and amygdala volumes in children and adults with childhood maltreatment-related posttraumatic stress disorder: A meta-analysis. Hippocampus 18(8):729–36.Google Scholar