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Spin coating is the process of generating a uniform coating film on a substrate by centrifugal forces during rotation. In the framework of lubrication theory, we investigate the axisymmetric film evolution and contact-line dynamics in spin coating on a partially wetting substrate. The contact-line singularity is regularized by imposing a Navier slip model. The interface morphology and the contact-line movement are obtained by numerical solution and asymptotic analysis of the lubrication equation. The results show that the evolution of the liquid film can be classified into two modes, depending on the rotational speed. At lower speeds, the film eventually reaches an equilibrium state, and we provide a theoretical description of how the equilibrium state can be approached through matched asymptotic expansions. At higher speeds, the film exhibits two or three distinct regions: a uniform thinning film in the central region, an annular ridge near the contact line, and a possible Landau–Levich–Derjaguin-type (LLD-type) film in between that has not been reported previously. In particular, the LLD-type film occurs only at speeds slightly higher than the critical value for the existence of the equilibrium state, and leads to the decoupling of the uniform film and the ridge. It is found that the evolution of the ridge can be well described by a two-dimensional quasi-steady analysis. As a result, the ridge volume approaches a constant and cannot be neglected to predict the variation of the contact-line radius. The long-time behaviours of the film thickness and the contact radius agree with derived asymptotic solutions.
The severe ice losses observed for European glaciers in recent years have increased the interest in monitoring short-term glacier changes. Here, we present a method for constraining modelled glacier mass balance at the sub-seasonal scale and apply it to ten selected glaciers in the Swiss Alps over the period 2015–23. The method relies on observations of the snow-covered area fraction (SCAF) retrieved from Sentinel-2 imagery and long-term mean glacier mass balances. The additional information provided by the SCAF observations is shown to improve winter mass balance estimates by 22% on average over the study sites and by up to 70% in individual cases. Our approach exhibits good performance, with a mean absolute deviation (MAD) to the observed seasonal mass balances of 0.28 m w.e. and an MAD to the observed SCAFs of 6%. The results highlight the importance of accurately constraining winter accumulation when aiming to reproduce the evolution of glacier mass balance over the melt season and to better separate accumulation and ablation components. Since our method relies on remotely sensed observations and avoids the need for in situ measurements, we conclude that it holds potential for regional-scale glacier monitoring.
This study aims to identify fathers’ profiles integrating food parenting practices (FPP) and physical activity parenting practices (PAPP).
Design:
We analysed cross-sectional data. The fathers completed the reduced FPP and PAPP item banks and socio-demographic and family dynamics (co-parenting and household responsibility) questionnaires. We identified fathers’ profiles via latent profile analysis. We explored the influence of social determinants, child characteristics and family dynamics on fathers’ profiles using multinomial logistic regression.
Setting:
Online survey in the USA.
Participants:
Fathers of 5–11-year-old children.
Results:
We analysed data from 606 fathers (age = 38 ± 8·0; Hispanic = 37·5 %). Most fathers self-identified as White (57·9 %) or Black/African American (17·7 %), overweight (41·1 %) or obese (34·8 %); attended college (70 %); earned > $47 000 (62·7 %); worked 40 hrs/week (63·4 %) and were biological fathers (90·1 %). Most children (boys = 55·5 %) were 5–8 years old (65·2 %). We identified five fathers’ profiles combining FPP and PAPP: (1) Engaged Supporter Father (n 94 (15·5 %)); (2) Leveled Father (n 160 (26·4 %)); (3) Autonomy-Focused Father (n 117 (19·3 %)); (4) Uninvolved Father (n 113 (18·6 %)) and (5) Control-Focused Father (n 122 (20·1 %)). We observed significant associations with race, ethnicity, child characteristics, co-parenting and household responsibility but not with education level, annual income or employment status. We observed significant pairwise differences between profiles in co-parenting and household responsibility, with the Engaged Supporter Father presenting higher scores in both measures.
Conclusions:
Understanding how fathers’ FPP and PAPP interact can enhance assessments for a comprehensive understanding of fathers’ influences on children’s health. Recognising the characteristics and differences among fathers’ profiles may enable tailored interventions, potentially improving children’s health trajectories.
Dean’s approximation for curved pipe flow, valid under loose coiling and high Reynolds numbers, is extended to study three-dimensional travelling waves. Two distinct types of solutions bifurcate from the Dean’s classic two-vortex solution. The first type arises through a supercritical bifurcation from inviscid linear instability, and the corresponding self-consistent asymptotic structure aligns with the vortex–wave interaction theory. The second type emerges from a subcritical bifurcation by curvature-induced instabilities and satisfies the boundary region equations. A connection to the zero-curvature limit was not found. However, by continuing from known self-sustained exact coherent structures in the straight pipe flow problem, another family of three-dimensional travelling waves can be shown to exist across all Dean numbers. The self-sustained solutions also possess the two high-Reynolds-number limits. While the vortex–wave interaction type of solutions can be computed at large Dean numbers, their branch remains unconnected to the Dean vortex solution branch.
While the majority of 2021 Capitol insurrection participants were white men, the media prominently highlighted the involvement of male conservative activists of color. However, we still know little about the perspectives of men in the general public regarding this event in our nation’s history, particularly across racial/ethnic and other identity groups. This project examines the influence of racialized anger and racial efficacy on self-identified male views toward the 2021 Capitol insurrection across racial/ethnic groups. We utilize the 2020 Collaborative Multiracial Post-Election Survey (CMPS), which was the only national, post-election dataset to yield responses on the Capitol insurrection across a large number of identity groups like men of color. Using the CMPS, we hypothesize that the level of racialized anger and racial efficacy will impact attitudes toward the 2021 Capitol insurrection for men across racial groups comparing men of color and their white male counterparts. We find racial anger has a negative effect on political attitudes about the 2021 Capitol insurrection across all groups of men, while racial efficacy has varied effects on certain men of color groups in comparison to white men. This paper underscores the importance of intersectionality in the study of public opinion formation and the effect of political attitudes like racial efficacy and racialized anger on non-traditional political engagement.
Grandparent childcare is important to support parents’ work/care reconciliation. Research has begun to identify relationships between grandparent childcare patterns and policy settings. However, this work is disparate and focused on childcare policy, with little engagement with the broader range of policies that shape grandparent childcare. A holistic approach to understanding the relationship between policies and grandparent childcare is important to capture the intergenerational dynamics of family decisions about childcare and the complementarities (or not) of policies in different domains. This scoping review identifies policies that directly aim to shape grandparents’ involvement in childcare and that indirectly shape configurations of care. Most literature focuses on childcare and parental leave policies’ impact on parental demand for grandparent childcare. But a wider, intergenerational, policy lens reveals that policies (such as retirement income policies) affect parents’ demand for, and grandparents’ supply of childcare, and that policies in different domains are not always aligned.
Patent ductus arteriosus is a common condition in preterm neonates, often necessitating medical or surgical intervention. This report presents a case of a preterm neonate born at 27 gestational weeks and who experienced patent ductus arteriosus rupture during a device closure procedure. Patent ductus arteriosus rupturing during device closure is rare and life threatening but can be successfully managed with prompt recognition and intervention.
On the upper reaches of the Tigris and Euphrates, archaeologists encounter evidence that challenges conventional understandings of early state formation as a transition from ‘small-scale, egalitarian’ to ‘large-scale, stratified’ societies. One such location is the Early Bronze Age cemetery of Başur Höyük, which presents evidence of grand funerary rituals—including ‘retainer burials’ and spectacular deposits of metallic wealth—in an otherwise small-scale, egalitarian setting. A further, puzzling feature of this cemetery is the preponderance of teenagers in the richest tombs. Here we describe the combined results of archaeological and anthropological analysis at Başur Höyük, including ancient DNA, and consider the challenges they pose to traditional accounts of early state formation.
There is significant focus on the global polycrisis currently – and rightfully so, considering the threat to societies around the world that converging environmental, social, political, and economic challenges pose. However, little is said about what comes after the polycrisis. Are there methods to address the polycrisis in ways that would inherently help establish a ‘better’ post-polycrisis period (PPP) (i.e. preserving more of what sustains the many dimensions of human wellbeing while maintaining the integrity of the biosphere and local ecosystems)? This article explores that question, examining potential interventions that could lead to less suffering both during the polycrisis period and PPP.
Technical summary
This article explores how polycrisis interventions can be designed to be the most effective in setting up a better post-polycrisis outcome, while also improving the polycrisis response potential. It starts by setting up a 2 × 2 matrix to explore interventions that (1) improve outcomes during the polycrisis (but not the post-polycrisis period [PPP]), (2) improve outcomes post-polycrisis (but not during the polycrisis); (3) improve neither, and (4) improve both. The article explores some relevant and timely examples in each of the four quadrants, with particular focus on the quadrant in which interventions improve outcomes both for the polycrisis period and PPP. Particular attention is given, within that quadrant, to: reducing nuclear arsenals, population degrowth, economic degrowth, strengthening local agriculture, low-tech and appropriate technologies, and cultivating deeper respect for Gaia. In conclusion, the article recognizes that although it may be difficult, even impossible, to proactively and effectively plan for the PPP, some measures can be taken even now. Further, failing to put this on societal agendas means planning for and addressing long-term wellbeing will only occur by chance, increasing the odds of an extended period of crisis and/or a loss of key knowledge and civilizational advances gained.
Social media summary
Are there interventions to improve human and ecological wellbeing both in the polycrisis and the period that comes after?
While the effects of technological change on deskilling and upskilling of the contemporary labor force have been intensely debated among economists and sociologists, historians have been more or less silent. Here, we historicize this debate by applying a set of HISCO-based measures to a recently homogenized set of aggregated census data for men in Italy from 1871 to 2011, coded in HISCO, to study the effects of waves of technological changes. With the transition from agriculture, via industry to services, we identify the main subprocesses and study occupational diversity and specialization, class formation, and skill development. The first industrial revolution saw modest growth in lower-skilled work in Italy, and a decline in unskilled work; the second, growth in lower- and higher-skilled work, and a decline in medium and unskilled work; the third, growth in lower- and higher-skilled work.
Several methods have been proposed for the synthesis of continuous outcomes reported on different scales, including the Standardised Mean Difference (SMD) and the Ratio of Means (RoM). SMDs can be formed by dividing the study mean treatment effect either by a study-specific (Study-SMD) or a scale-specific (Scale-SMD) standard deviation (SD). We compared the performance of RoM to the different standardisation methods with and without meta-regression (MR) on baseline severity, in a Bayesian network meta-analysis (NMA) of 14 treatments for depression, reported on five different scales. There was substantial between-study variation in the SDs reported on the same scale. Based on the Deviance Information Criterion, RoM was preferred as having better model fit than the SMD models. Model fit for SMD models was not improved with meta-regression. Percentage shrinkage was used as a scale-independent measure with higher % shrinkage indicating lower heterogeneity. Heterogeneity was lowest for RoM (20.5% shrinkage), then Scale-SMD (18.2% shrinkage), and highest for Study-SMD (16.7% shrinkage). Model choice impacted which treatment was estimated to be most effective. However, all models picked out the same three highest-ranked treatments using the GRADE criteria. Alongside other indicators, higher shrinkage of RoM models suggests that treatments for depression act multiplicatively rather than additively. Further research is needed to determine whether these findings extend to Patient- and Clinician-Reported Outcomes used in other application areas. Where treatment effects are additive, we recommend using Scale-SMD for standardisation to avoid the additional heterogeneity introduced by Study-SMD.
The chemistry of combining the simulation hypothesis (which many believe to be a modern variation of skepticism) and manipulation arguments will be explored for the first time in this paper. I argue: If we take the possibility that we are now in a simulation seriously enough, then contrary to a common intuition, manipulation very likely does not undermine moral responsibility. To this goal, I first defend the structural isomorphism between simulation and manipulation: Provided such isomorphism, either both of them are compatible with moral responsibility, or none of them is. Later, I propose two kinds of reasons – i.e., the simulator-centric reason and the simulatee-centric reason – for why we have (genuine) moral responsibilities even if we are in a simulation. I close by addressing the significance of this paper in accounting for the relevance of artificial intelligence and its philosophy, in helping resolve a long-locked debate over free will, and in offering one reminder for moral responsibility specialists.
The proto-oncogene tyrosine kinase receptor encoded by the W locus (CD-117) has been confirmed to be critical to the processes of germ cell proliferation, migration and survival in the rodent. The purpose of the present study was to examine the expression of germ cell-specific CD-117 marker in testis and germ line stem cells (GSCs). The aim of this study was analysis of CD-117 expression as germ cell marker in the seminiferous tubule of mice.
Materials and Methods:
In this experimental study, we employed a comprehensive array of techniques to scrutinize the expression of CD-117. Our analysis encompassed the utilization of immunocytochemistry, immunohistochemistry, Fluidigm real-time Reverse Transcription Polymerase Chain Reaction (RT-PCR), and flow cytometry methodologies.
Results:
The Immuno-history-fluorescent analysis revealed the distribution of the germ cell marker CD-117 in the differentiated compartment of seminiferous tubules. High-magnification of confocal microscopy analysis showed surface expression of CD-117 in testis section. Whereas isolated GSCs colonies clearly express the germ-specific protein CD-117, TSCs (testicular stromal cells) were negative for this marker. Fluidigm real-time RT-PCR result demonstrated a significant expression (P < 0.001) of CD-117 in the neonate and adult GSCs compared to TSCs cells. Similarly, flow cytometry analysis confirmed expression of CD-117 in the GSCs colonies and testis cells.
Conclusion:
These results discriminate in spite of stage-specific ectopic, expression of CD-117 is a specific germ cell marker for proliferation and differentiation of GSCs into sperm, and can be beneficial for understanding of the signalling pathways related to differentiation of GSCs.
Gravity-driven film flow in circular pipes with isolated topography was examined with fluorescence imaging for three flow rates, two angles of inclination, and four topography shapes. The time-averaged free surface response in the vicinity of the topography depended on flow rate, inclination angle and topography shape. For some flow conditions, the time-averaged free surface included a capillary ridge, and for a subset of those conditions, a series of capillary waves developed upstream with a spacing often approximated by half the capillary length. In contrast to film flow over planar topography, the capillary ridge often formed downstream of the topography, and for the lowest flow rate over rectangular step down topography, the free surface developed a steady overhang along the downstream face of the topography. Possible dynamic causes of the unique film flow behaviour in circular pipes are discussed. Transient free surface fluctuations were observed at half the magnitude reported in film flow over corrugated circular pipes, and local maxima in transient magnitude corresponded to axial locations of inflection points in the time-averaged free surface. Local maxima are related to low surface pressure regions that vary in location and amplitude. Rectangular step down topography generated an extra ridge of fluid that formed on top of the capillary ridge for flow conditions, resulting in a capillary ridge downstream of the step. The extra ridge varied in temporal duration and spatial extent, and finds no comparison in planar film flow. No evidence of periodic behaviour was detected in the transient film response.
Climate change is one of the most salient issues in current international politics. In all but the most optimistic of scenarios, it has the potential to severely impact human life in many parts of the world. Production and consumption patterns under the current liberal economic order contribute significantly to the climate crisis. Yet the norms and ideas that guide climate policy under this order are remarkably persistent in the face of climate change. This article explores why these norms have not yet been challenged, and how theories of international relations help understand the absence of such challenges.
Technical summary
Multilateral climate policy has institutionalized a set of norms that may be summarized as liberal environmentalism. Liberal environmentalism presumes that economic growth and environmental protection are not mutually exclusive, but prerequisites for each other, thereby connecting the economic order with environmental policy. This article argues that there is a distinct mismatch between the climate crisis and the stickiness of liberal environmentalism. Although the natural system to be governed is in crisis, the political and normative system tasked with governing it is not. The article thus inquires how crises come about by examining why they sometimes do not. It compares theoretical insights borrowed from liberal institutionalism, constructivism, and neo-realism and explores what may be missing from such approaches to fully grasp the nature of crises in international politics. The article finds that liberal environmentalist norms emerged in the 1990s, cascaded in the early 2000s and became institutionalized in the Copenhagen era, culminating in the Paris Agreement. They are likely to remain unaffected by the current polycrisis in international relations, because institutionalized norms are often resistant to change. Liberal environmentalist norms are now deeply embedded in contemporary climate governance, meaning that they can only be challenged through persistent norm entrepreneurship.
Social media summary
Liberal environmentalism persists in global climate policy because of institutionalized norms and the discursive reproduction of these norms.
Inspired by the symposium editors’ call to reclaim and reimagine some or all of the space that is currently populated by international criminal law (ICL), we take this opportunity to engage in what we are calling feminist dreaming—that is, we seek to reimagine accountability as it could be, viewed through a feminist lens. Drawing on the work of standpoint feminists, such as Nancy Hartsock, we examine how the punitive mindset has taken hold from the top down, with little regard for or consideration of what those most acutely harmed, who are often women, want. Instead, international actors, often elites educated in the West, have mandated a certain ideal of justice from above through legal principles like the duty to prosecute. This focus on punishment narrows the lens through which “justice” is perceived and administered. It imposes a single perspective—that of a supposedly uniform global community—on affected communities, preempting other forms of justice that may have greater healing potential, including those with restorative or redistributive aims. In this sense, ICL can be seen as inflicting a form of epistemic violence.1 Instead of inquiring into, and respecting, the perspectives of victims, survivors, and their broader communities, it seeks to impose a viewpoint: only punishment will produce justice. This contribution takes a small step toward reimagining justice under the international legal order.2 We employ a standpoint feminist lens to first surface some of the harms ICL inflicts and then suggest a course correction that centers the voices of the most marginalized—in other words, we begin feminist dreaming.
Health Law as Private Law delves into the complex relationship between private law and health care. During the COVID-19 pandemic, the importance of public ordering and state-created rules was evident, yet this work reveals the equally important role of private agreements in shaping health care policy. The volume's five sections – theory and structure, reproductive care, costs and financing, innovation and institutions, contracts and torts – include innovative conceptualizations and approaches to applying private law to health law. Chapters authored by leading experts explore how private law can be utilized to address significant health care and public health problems, and to achieve much-needed health care reform. Comprehensive and timely, Health Law as Private Law opens new pathways that will influence future policy, jurisprudence, and regulation. This title is also available as open access on Cambridge Core.