Salmonella Infections: Clinical, Immunological and Molecular Aspects

Duncan Maskell

doi:10.1017/CBO9780511525360

Salmonella Infections

Clinical, Immunological and Molecular Aspects

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Salmonella enterica encompasses a diverse range of bacteria that cause a spectrum of diseases in many hosts. Advancements in prevention and treatment of S. enterica infections have at times been hampered by compartmentalization of research efforts and lack of multidisciplinary approaches. This book attempts to cover a diverse range of topics related to the biology of S. enterica infections, including epidemiological and clinical aspects, molecular pathogenesis, immunity to disease and vaccines. S. enterica infections are important zoonoses and therefore material on infections of animals and public health issues have also been considered. Each chapter can be read independently, but the full contents of the book will provide the reader with up-to-date knowledge on all the key aspects of salmonellosis in humans and animals. It will therefore be of interest to graduate students and researchers, as well as to clinicians, whose research focuses on this important pathogen.

'Whether your interests lie in human or animal infection, in the virulence factors that make Salmonella such a successful pathogen, or even in the ability of Salmonella to be used for the immunotherapy of cancer, this book should prove a useful addition to bookshelves in libraries and research labs.'

Jay Hinton - Institute of Food Research

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Contents

Frontmatter
pp i-viii
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Contents
pp ix-xiii
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List of contributors
pp xiv-xvi
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Preface
pp xvii-xviii
- By Pietro Mastroeni, Senior Lecturer in the Department of Veterinary Medicine, University of Cambridge
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1 - Epidemiological and clinical aspects of human typhoid fever
pp 1-24
- By Christopher M. Parry, Department of Medical Microbiology and Genitourinary Medicine, Duncan Building, University of Liverpool, Daulby Street, Liverpool L69 3GA, UK
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2 - Antibiotic resistance in Salmonella infections
pp 25-56
- By Fiona J. Cooke, Centre for Molecular Microbiology and Infection, Imperial College of Science, Technology and Medicine, University of London, Exhibition Road, South Kensington, London W7 2AZ, UK, John Wain, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambs CB10 1SA, UK
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3 - Host-specificity of Salmonella infections in animal species
pp 57-88
- By Timothy S. Wallis, Institute for Animal Health, Compton, Newbury, Berkshire RG20 7NN, UK
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4 - Public health aspects of Salmonella enterica in food production
pp 89-116
- By Tom Humphrey, Department of Clinical Veterinary Science, University of Bristol, Langford House, Langford, North Somerset BS40 5DU, UK
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5 - The Salmonella genome: a global view
pp 117-145
- By Anne L. Bishop, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambs CB10 1SA, UK, Gordon Dougan, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambs CB10 1SA, UK, Stephen Baker, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambs CB10 1SA, UK
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6 - Pathogenicity islands and virulence of Salmonella enterica
pp 146-172
- By Michael Hensel, Institut für Klinische Mikrobiologie, Immunologie und Hygiene, Universität Erlangen-Nuemberg, Wasserturmstr. 3-5, D-91054 Erlangen, Germany
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7 - In vivo identification, expression and function of Salmonella virulence genes
pp 173-206
- By Helene Andrews-Polymenis, Department of Medical Microbiology & Immunology, 407 Reynolds Medical Building, Texas A&M University SHSC, College Station, TX 77843-1114, USA, Caleb W. Dorsey, Dept. Med. Microbiol. & Immunol., 407 Reynolds Medical Building, Texas A&M University SHSC, College Station, TX 77843-1114, USA, Manuela Raffatellu, Dept. Med. Microbiol. & Immonol., School of Medicine, University of California at Davis, One Shields Ave., Davis, CA 95616-8645, Andreas J. Bäumler, Department of Medical Microbiology & Immunology, School of Medicine, University of California at Davis, One Shields Ave., Davis, CA 95616-8645, USA
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8 - Mechanisms of immunity to Salmonella infections
pp 207-254
- By Pietro Mastroeni, Senior Lecturer in the Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES, UK
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9 - Interactions of S. enterica with phagocytic cells
pp 255-278
- By Bruce D. McCollister, Department of Microbiology, University of Colorado Health Sciences Center, B175, Room 4615, 4200 E. 9th Ave., Denver, CO 80262, USA, Andres Vazquez-Torres, Department of Microbiology, University of Colorado Health Sciences Center, B175, Room 4615, 4200 E. 9th Ave., Denver, CO 80262, USA
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10 - Interactions between Salmonella and dendritic cells: what happens along the way?
pp 279-298
- By Cecilia Johansson, Department of Clinical Immunology, University of Goteborg, Guldhedsgatan 10A, Goteborg SE-413 46, Sweden, Malin Sundquist, Department of Clinical Immunology, University of Goteborg, Guldhedsgatan 10A, Goteborg SE-413 46, Sweden, Mary Jo Wick, Department of Clinical Immunology, University of Goteborg, Guldhedsgatan 10A, Goteborg SE-413 46, Sweden
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11 - Immunity to Salmonella in domestic (food animal) species
pp 299-322
- By Paul Wigley, Institute for Animal Health, Compton, Newbury, Berkshire RG20 7NN, UK, Paul Barrow, Institute for Animal Health, Compton, Newbury, Berkshire RG20 7NN, UK, Bernardo Villarreal-Ramos, Institute for Animal Health, Compton, Newbury, Berkshire RG20 7NN, UK
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12 - Newer vaccines against typhoid fever and gastrointestinal salmonelloses
pp 323-336
- By Richard A. Strugnell, Department of Microbiology & Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia, Odilia L. C. Wijburg, Department of Microbiology & Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
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13 - S. enterica-based antigen delivery systems
pp 337-370
- By José A. Chabalgoity, Laboratory for Vaccine Research, Department of Biotechnology, Instituto de Higiene, Facultad de Medicina, Avda. A. Navarro 3051, Montevideo CP 11600, Uruguay
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Index
pp 371-381
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Plate section
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Salmonella Infections

Clinical, Immunological and Molecular Aspects

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Contents

Frontmatter
pp i-viii

Contents
pp ix-xiii

List of contributors
pp xiv-xvi

Preface
pp xvii-xviii

1 - Epidemiological and clinical aspects of human typhoid fever
pp 1-24

2 - Antibiotic resistance in Salmonella infections
pp 25-56

3 - Host-specificity of Salmonella infections in animal species
pp 57-88

4 - Public health aspects of Salmonella enterica in food production
pp 89-116

5 - The Salmonella genome: a global view
pp 117-145

6 - Pathogenicity islands and virulence of Salmonella enterica
pp 146-172

7 - In vivo identification, expression and function of Salmonella virulence genes
pp 173-206

8 - Mechanisms of immunity to Salmonella infections
pp 207-254

9 - Interactions of S. enterica with phagocytic cells
pp 255-278

10 - Interactions between Salmonella and dendritic cells: what happens along the way?
pp 279-298

11 - Immunity to Salmonella in domestic (food animal) species
pp 299-322

12 - Newer vaccines against typhoid fever and gastrointestinal salmonelloses
pp 323-336

13 - S. enterica-based antigen delivery systems
pp 337-370

Index
pp 371-381

Plate section

Metrics

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Salmonella Infections

Clinical, Immunological and Molecular Aspects

Book description

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