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3 - Host-specificity of Salmonella infections in animal species

Published online by Cambridge University Press:  04 December 2009

Duncan Maskell
By
Timothy S. Wallis
Edited by
Pietro Mastroeni
Duncan Maskell
Affiliation:
University of Cambridge
Timothy S. Wallis
Affiliation:
Institute for Animal Health, Compton, Newbury, Berkshire RG20 7NN, UK
Pietro Mastroeni
Affiliation:
University of Cambridge
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Summary

INTRODUCTION

The bacterial species Salmonella enterica subspecies enterica can be divided into over 2400 antigenically distinct serovars and the pathogenicity of most of these serovars is undefined. The majority of incidents of salmonellosis in humans and domestic animals are caused by relatively few serovars and these can be subdivided into three groups on the basis of host prevalence. The first group consists of host-specific serovars. These typically cause systemic disease in a limited number of phylogenetically related species. For example, S. enterica serovar Typhi, serovar Gallinarum and serovar Abortusovis are almost exclusively associated with systemic disease in humans, fowl and sheep respectively. The second group consists of host-restricted strains. These are primarily associated with one or two closely related host species but may also infrequently cause disease in other hosts. For example, S. enterica serovar Dublin and serovar Choleraesuis are generally associated with severe systemic disease in ruminants and pigs respectively (Sojka et al., 1977). However, these serovars are potentially capable of infecting other animal species and humans. The third group consists of the ubiquitous S. enterica serovars, such as Typhimurium and Enteritidis that usually induce gastroenteritis in a broad range of unrelated host species.

Clearly the nature and severity of Salmonella infections in different animal species varies enormously and is influenced by many factors including the infecting Salmonella serovar, strain virulence, infecting dose, host animal species, age and immune status of the host, and the geographical region. All these factors are likely to inter-relate.

Type
Chapter
Information
Salmonella Infections
Clinical, Immunological and Molecular Aspects
 , pp. 57 - 88
Publisher: Cambridge University Press
Print publication year: 2006

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Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

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Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

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