The volume filtering of the governing equations of a particle-laden flow allows for simulating the fluid phase as a continuum, and accounting for the momentum exchange between the fluid and the particles by adding a source term in the fluid momentum equations. The volume filtering of the Navier–Stokes equations allows consideration of the effect that particles have on the fluid without further assumptions, but closures arise of which the implications are not fully understood. It is common to either neglect these closures or model them using assumptions of which the implications are unclear. In the present paper, we carefully study every closure in the volume-filtered fluid momentum equation and investigate their impact on the momentum and energy transfer dependent on the filtering characteristics. We provide an analytical expression for the viscous closure that arises because the filter and spatial derivative in the viscous term do not commute. An analytical expression for the regularization of the particle momentum source of a single sphere in the Stokes regime is derived. Furthermore, we propose a model for the subfilter stress tensor, which originates from filtering the advective term. The model for the subfilter stress tensor is shown to agree well with the subfilter stress tensor for small filter widths relative to the size of the particle. We show that, in contrast to common practice, the subfilter stress tensor requires modelling and should not be neglected. For filter widths comparable to the particle size, we find that the commonly applied Gaussian regularization of the particle momentum source is a poor approximation of the spatial distribution of the particle momentum source, but for larger filter widths, the spatial distribution approaches a Gaussian. Furthermore, we propose a modified advective term in the volume-filtered momentum equation that consistently circumvents the common stability issues observed at locally small fluid volume fractions. Finally, we propose a generally applicable form of the volume-filtered momentum equation and its closures based on clear and well-founded assumptions. Based on the new findings, guidelines for point-particle simulations and the filter width with respect to the particle size and fluid mesh spacing are proposed.

The article presents the results of the last decade of archaeological and epigraphic research, which clarified the history of the polities of the ancient Maya sites of Holmul and Naranjo during the expansion of the Dzibanche royal dynasty in the eastern area of the Department of Peten, Guatemala, from the second half of the sixth century through the first half of the seventh century a.d. The discussion centers on the textual and material indicators of the geopolitical contacts of the royal families of Sak Chuwen of Naranjo and Chak Tok Wayaab of Holmul, including changes in polychrome pottery and hieroglyphic inscriptions, in particular, rhetoric of good governance and political loyalty. In the case of Holmul, the transformation affects the urban landscape of the site. New data clarify the relationship between Holmul and Naranjo during the initial period of their subordination to the kings of Dzibanche. The emerging picture of these secondary alliances and hierarchies within the Kaanu'l domain is essential for a better understanding of Classic Maya political systems at local and regional levels.

En la Mesa Redonda de Palenque de 2004 Erik Velásquez propuso que los gobernantes mayas que portaban el glifo emblema de Kaanuˀl pudieron haber residido durante el Clásico Temprano en Dzibanché, pues no existen referencias que los vinculen con Calakmul antes de 631 d.C. Aquí revisamos los datos sobre su presencia en Dzibanché y otros asentamientos de la región. Argumentos de distinta naturaleza que apoyan este escenario se publicaron desde 2005 hasta 2016, incluyendo los hallazgos de Xunantunich (Helmke y Awe 2016a, 2016b), que permiten conjeturar que una facción disidente de la dinastía se separó de Dzibanché y fundó en 635 d.C. una sede alternativa en Calakmul. Ello produjo el panorama que proponemos en el Clásico Tardío, donde había mandatarios simultáneos de la dinastía Kaanuˀl en el sur de Campeche y en el sur de Quintana Roo, toda vez que en Dzibanché seguían residiendo gobernantes Kaanuˀl al menos hasta el siglo VII.

Inference in spatial and spatio-temporal models can be challenging for a variety of reasons. For example, non-Gaussianity often leads to analytically intractable integrals; we may be in a ‘big’ data setting, whereby the number of observations renders traditional methods too computationally expensive; we may wish to make inferences over spatial supports that are different to those of our measurements; or, we may wish to use a statistical model whose likelihood function is either unavailable or computationally intractable. In this thesis, I develop several techniques that help to alleviate these challenges.

Previous studies investigating behavioural health screening processes have focused on selected diagnoses within paediatric cardiology and focused on a smaller number of potential concerns. We developed and administered a brief survey in our paediatric heart centre to assess the presence of a wider variety of behavioural health concerns and to connect patients with resources. A cohort of 305 patients aged 2–29 years (M = 11.97 years; SD = 6.00 years; 50.49% female), representing a variety of indications for a cardiology clinic visit, or a parent, completed a survey of 14 common behavioural health concerns. Behavioural health concerns were included based on practice patterns within paediatric psychology. Respondents indicated if they were currently receiving behavioural health services and if they were interested in behavioural health follow-up. Surveys were administered during check in and collected by clinic staff. A behavioural health provider attempted to reach all those who indicated interest by phone. Approximately 45% of the sample endorsed one or more behavioural health concerns and 30.16% of the sample endorsed at least one concern but were not already connected to services. Only 27.17% of this group requested follow-up. Most commonly endorsed concerns were anxiety, sleep problems, depressed/irritable mood, and somatic complaints. Survey results converge with existing literature to indicate that behavioural health concerns are common among youth seen in a paediatric cardiology clinic but most patients are not connected to appropriate services. Screening programmes can help meet this need but challenges remain. Clinical implications and future directions are discussed.

Hereditary connective tissue diseases have different risks of aortic dissection depending on the causative gene. We report a family with no extravascular phenotype and a clinical diagnosis of familial thoracic aortic aneurysm and dissection, but genetic testing confirmed p.Tyr470Cys in TGFBR2, which is typically the responsible gene for Loeys–Dietz syndrome. Validation of the clinical diagnosis by genetic testing is warranted.

‘Biological’ and ‘social’ perspectives in psychiatry have exchanged dominance at different times in the history of our field and are sometimes erroneously viewed as being contrasting and mutually exclusive paradigms. We argue that the arbitrary ‘biological/social’ divide in psychiatry is misleading, unhelpful, and ultimately a false one. We propose that the evolutionary perspective provides a necessary framework and metatheory that can bridge this apparent schism in psychiatric thinking, providing novel and useful insights into how we can better assess, diagnose, and treat our patients.

The Kaanuˀl dynasty ruled a hegemonic state with political influence over much of the Classic Maya Lowlands between a.d. 520 and 751. The present article introduces the subject for a special section of the journal, which refocuses attention on the archaeological zone of Dzibanche in southern Quintana Roo, Mexico, where new data are emerging about the origins of the Kaanuˀl dynasty, its urban organization, and its connections to neighboring centers. In this article, we present new data from a recent lidar survey as well as from previous work by Enrique Nalda's Instituto Nacional de Antropología e Historia (INAH) project to reevaluate Dzibanche's characteristics vis-à-vis its rise as a kingdom with far-reaching political influence. We complement these archaeological data with epigraphic information from new monuments and reanalysis of existing ones based on 3D scanning to update the list of Dzibanche rulers. We then revisit the chronology of Dzibanche's royal burials proposing correlations with known Early Classic Kaanuˀl rulers. Overall, the contributions to this special section present new perspectives on the Kaanuˀl's rise to power and its relationship with distant vassals in the crucial period of expansion into northern Peten, leading to the defeat of Tikal and eventually to its transition to a new dynastic seat at Calakmul in the a.d. 630s.

Medical dramas such as Grey's Anatomy influence young people's career aspirations, creating unrealistic expectations. This article examines the gap between these portrayals and the reality of medical practice, highlighting challenges such as rigorous training and high stress. Using Italy's ‘numero chiuso’ (‘closed number’) system as a case study, it addresses the global issue of intense competition in medical school admissions. The article advocates for realistic education and better support to prepare future healthcare professionals.

We prove a nonabelian variant of the classical Mordell–Lang conjecture in the context of finite- dimensional central simple algebras. We obtain the following result as a particular case of a more general statement. Let K be an algebraically closed field of characteristic zero, let $B_1,\dots ,B_r\in \mathrm {GL}_m(K)$ be matrices with multiplicatively independent eigenvalues and let V be a closed subvariety of $\mathrm {GL}_m(K)$ not passing through zero. Then there exist only finitely many elements of $\mathrm {GL}_m(K)$ of the form $B_1^{n_1}\cdots B_r^{n_r}$ (as we vary $n_1,\dots ,n_r$ in $\mathbb {Z}$) lying on the subvariety V.

In 2020, the Israeli Supreme Court held section 4 of the Law on Prevention of Infiltration and Ensuring the Departure of Infiltrators from Israel, also known as the Deposit Law, to be unconstitutional. Among other provisions, that law required 36 per cent of the wages of foreign workers to be paid into a dedicated account and returned when the person left the country. For years the Deposit Law had a negative impact on the lives of asylum seekers because of its racialised, gendered, ethnonational and religious impact. Its intersectional impact illustrates cultural, structural and systematic violence, which has been particularly punitive for asylum-seeking women, who are more exposed to sexual and gender-based violence (SGBV).

In this context, this interdisciplinary qualitative and empirical research article draws from empirical fieldwork conducted in Israel to understand the intersectional impact of the law. It therefore conducts a theoretical examination of the literature and connects that to the empirical study. Thus, the article empirically and theoretically investigates (i) the extent to which state-created categories foster unlawful multilayered and multilevel forms of vulnerability and discrimination; (ii) the intersectional impact of the Deposit Law and how it is related to SGBV; and (iii) how state-created intersecting vulnerabilities can be diagnosed. The overall goal of the article is to indicate the intertwined nature and interconnection between state-created categories and the inevitability of state-created vulnerabilities.

Tidal flooding occurs when coastal water levels exceed impact-based flood thresholds due to tides alone, under average weather conditions. Transitions to tidal flood regimes are already underway for nuisance flood severities in harbours and bays and expected for higher severities in coming decades. In the first such regional assessment, we show that the same transition to tidally forced floods can also be expected to occur in Australian estuaries with less than 0.1 m further sea-level rise. Flood thresholds that historically used to only be exceeded under the combined effects of riverine (freshwater) and coastal (salt water) influences will then occur due to high tides alone. Once this tidal flooding emerges, it is projected to become chronic within two decades. Locations most at-risk of the emergence of tidal flooding and subsequent establishment of chronic flood regimes are those just inside estuary entrances. These locations are exemplified by low freeboard, the vertical distance between a flood threshold and a typical high tide level. We use a freeboard-based analysis to estimate the sea-level rise required for impacts associated with official flood thresholds to occur due to tides alone. The resultant tide-only flood frequency estimates provide a lower bound for future flood rates.