Multiple factors aligning in 2025 implicate challenges to vaccines as a primary public health intervention. Anti-vaccine proponents seek to recast immunization policies in promotion of perceived individual liberties. Recalibrating national vaccine approaches, however, runs counter to long-standing public health laws and policies grounded in a core truth: safe and effective vaccines save lives.

Evidence synthesis is increasingly recognised as an essential element of the provision and use of expert advice in areas of public reasoning and decision-making.1 Synthesis here refers to an authoritative account of the best available knowledge in a field or fields, relevant to a question of policy interest and accessible to all interested audiences. Synthesis as a practice is well established in many areas of science and medicine. Although less frequent in the humanities, recent examples from funders and the British Academy illustrate increasing recognition of its importance.2 This article outlines why synthesis matters and, while pointing to some systemic challenges, shows how it can be done. It illustrates the findings from the literature with practical material from two recent projects led by the authors.

Dementia is represented as a condition deserving urgent policy attention. In the United Kingdom (UK) substantial resources have been invested in it, including in earlier intervention and in basic science. This selective narrative review explores England’s national dementia policy and practices. It uses Bacchi’s framework of questions, grounded in a Foucauldian understanding of governmentality, to understand how policy initiatives, service re-orientation and lobbying campaigns shape dementia as a problem. This ‘What is the Problem Represented to Be’ (WPR) analytic approach helps explain why prevention has often been overlooked and reminds us that not all ‘stakeholders’ have the same motivations. Our preliminary conclusions are that Bacchi’s approach does elucidate the representation of dementia and illuminates how a ‘medicalindustrial-charity-complex’ shapes the representation of dementia. Bacchi’s approach could be used to construct an agenda for change in dementia research and care.

Vaccination is one of the most cost-effective and successful public health interventions to prevent infectious diseases. Governments worldwide have tried to optimize vaccination coverage, including using vaccine mandates. This review of recent literature and policy aims to provide a comprehensive overview of Malaysia’s childhood vaccination landscape. The document analysis was used to identify and examine information from government policy documents, official government media statements, mainstream news content, and research papers. Content analysis was then employed to analyze the gathered information. Despite the successes of Malaysia’s National Immunization Programme, a resurgence of vaccine-preventable diseases has raised concerns about vaccine hesitancy and refusal. Several contributing factors have been identified, including a preference for alternative medicines, doubts about halal status, fear of vaccine injury, concerns about the vaccines’ contents, conspiracy theories, as well as convenience and access barriers. While various initiatives have been implemented, Malaysia may consider using vaccine mandates, as several countries have recently done, as a potential policy intervention to address these challenges. This review benefits policymakers, epidemiologists, as well as researchers involved in regional or global policy planning and advocacy efforts. It also offers comprehensive insights into designing effective interventions and making informed policy decisions regarding childhood vaccination programmes.

Interest groups are an important influence in the subnational policymaking process. Previously, environmental policy scholars measured the strength of environmental groups in the American policymaking subnational process by using proxies like state-level group membership in major nationwide environmental organizations (e.g., Sierra Club). Although these prior measures of group strength have face validity, recent scholarship suggests that the utilization of group financial resources is a better measure of the influence of interest groups in state-level models. We take this approach and provide a new way to measure state-level environmental interests by using aggregated financial information (income and assets) from Internal Revenue Service (IRS) data obtained via the National Center for Charitable Statistics (NCCS). This measure provides several advantages over previous approaches because it varies over time, is derived from easily accessible public data, includes a greater diversity of environmental organizations, and it is considered reliable by prior scholars. We demonstrate its empirical value by deploying our measure in a model of state policy adoption. We encourage researchers to further utilize this new measure in their analysis of environmental advocacy at the subnational level.

Eastern Europe and Central Asia (EECA) represents a diverse region facing complex healthcare challenges, including resource constraints, fragmented systems, and limited access to evidence-based decision-making tools. Health technology assessment (HTA) offers a critical framework for addressing these issues by informing efficient allocation of healthcare resources. In April 2024, HTA International (HTAi) convened a policy dialogue in Astana, Kazakhstan, bringing together stakeholders from 12 EECA countries and international experts to discuss HTA advancement in the region. The dialogue highlighted systemic barriers, including political instability, capacity shortages, and fragmented data sources while exploring successful HTA implementation models in some countries. Participants emphasized the importance of political commitment, institutional frameworks, and capacity building, alongside fostering stakeholder collaboration. International organizations such as HTAi and WHO were recognized as vital enablers for technical support and knowledge sharing. Key outcomes included actionable recommendations: strengthening political advocacy, developing legal and institutional frameworks, investing in workforce development, and enhancing multistakeholder engagement. The dialogue underscored HTAi’s role in catalyzing regional collaboration, providing platforms for discussion, and offering resources for capacity building. Future initiatives will focus on addressing structural weaknesses, promoting transparency, and embedding HTA into national healthcare systems to ensure equitable and evidence-based decisions. The findings reinforce the potential of HTA to enhance healthcare policy and planning in EECA, fostering resilient systems that better meet population health needs despite ongoing challenges.

Food insecurity (also known as food poverty) is the inability to afford or access a healthy diet. It has become recognised as a public health emergency and is a priority in the context of the environmental, geopolitical and socio-economic implications on businesses, households and civic society. This review paper aims to discuss the merits of collecting food insecurity data and its importance in informing cross-sectoral government and others’ understanding, policymaking and action on hunger. The review paper’s key findings are that concerted action on measuring and mapping food insecurity with the aim of eliminating or reducing its prevalence represents a triple win for government, business and citizens. However, measurement does not provide solutions to food insecurity but contributes importantly to understanding its extent and severity to inform and evaluate proffered solutions. Government, business and food insecurity researchers and commentators cannot merely continue to simply describe food poverty - but must effect meaningful change amidst our communities to improve life quality in a timely way for those experiencing acute and chronic hunger. This is best done by addressing the structural causes of food insecurity through economically, socially and culturally fair and appropriate policy levers, requiring cross-sectoral collaboration. Ultimately, food insecurity requires a long-term, sustainable solution that addresses the policy issues under focus: low income, under/unemployment, rising food prices and Welfare Reform, informed by routine, Government-supported monitoring and reporting of the extent of food poverty among our citizens.