Angiogenesis ensures the success of cancer growth. This enlargement of the vascular system feeding a tumor is induced by tumor angiogenic factors (TAFs), which are molecular messengers emitted by starving cancer cells. We apply a recently developed angiogenesis model to study the influence of variations in the TAF generation rate on vascular growth and to analyze the effects of changing the threshold for endothelial cell transformation, which is a crucial parameter in the description of this process.

A series of 44 samples of bone wedges of human origin, intended for allograft openwedge osteotomy and obtained without particular precautions during hip arthroplasty were re-examined. After viral inactivity chemical treatment, lyophilisation and radio-sterilisation (intended to produce optimal health safety), the compressive strength, independent of age, sex and the height of the sample (or angle of cut), proved to be too widely dispersed [10 − 158 MPa] in the first study. We propose a method for selecting samples which takes into account their geometry (width, length, thicknesses, cortical surface area). Statistical methods (Principal Components Analysis PCA, Hierarchical Cluster Analysis, Multilinear regression) allowed final selection of 29 samples having a mean compressive strength σmax = 103 MPa ± 26 and with variation [61 − 158 MPa] . These results are equivalent or greater than average materials currently used in openwedge osteotomy.

This study is to look at the distribution of current densities in proton exchange membrane fuel cells (PEMFC) to enable optimisation of fuel cell performance. The feasibility of using a new measurement technique of the local magnetic field, in the conductive plates of the cell was studied. The magnetic field is measured throughout the cell using the Maxwell equations and the current densities calculated. The measurement system and its validation are outlined in the first section. The next section outlines the experimental current density distribution within the cell, operating under standard conditions and special configurations, such as the partially active membrane electrodes assembly (MEA). Using a Matlab or Femlab model of the cell, (which is briefly outlined) our experiments are compared and an attempt made to explain the distribution of the current densities. Finally recent developments of the device are described, which will be used in several tests of PEMFC small stacks.