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Basal metabolic rate studies in humans: measurement and development of new equations

Published online by Cambridge University Press:  02 January 2007

CJK Henry
CJK Henry*
Affiliation:
School of Biological and Molecular Sciences, Oxford Brookes University, Gipsy Lane Campus, Oxford OX3 0BP, UK
*
*Corresponding author: Email [email protected]
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Abstract

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Objective

To facilitate the Food and Agriculture Organization/World Health Organization/United Nations University Joint (FAO/WHO/UNU) Expert Consultation on Energy and Protein Requirements which met in Rome in 1981, Schofield et al. reviewed the literature and produced predictive equations for both sexes for the following ages: 0–3, 3–10, 10–18, 18–30, 30–60 and >60 years. These formed the basis for the equations used in 1985 FAO/WHO/UNU document, Energy and Protein Requirements.

While Schofield's analysis has served a significant role in re-establishing the importance of using basal metabolic rate (BMR) to predict human energy requirements, recent workers have subsequently queried the universal validity and application of these equations. A survey of the most recent studies (1980–2000) in BMR suggests that in most cases the current FAO/WHO/UNU predictive equations overestimate BMR in many communities. The FAO/WHO/UNU equations to predict BMR were developed using a database that contained a disproportionate number – 3388 out of 7173 (47%) – of Italian subjects. The Schofield database contained relatively few subjects from the tropical region.

The objective here is to review the historical development in the measurement and application of BMR and to critically review the Schofield et al. BMR database presenting a series of new equations to predict BMR.

Design

This division, while arbitrary, will enable readers who wish to omit the historical review of BMR to concentrate on the evolution of the new BMR equations.

Setting

BMR data collected from published and measured values.

Subjects

A series of new equations (Oxford equations) have been developed using a data set of 10 552 BMR values that (1) excluded all the Italian subjects and (2) included a much larger number (4018) of people from the tropics.

Results

In general, the Oxford equations tend to produce lower BMR values than the current FAO/WHO/UNU equations in 18–30 and 30–60 year old males and in all females over 18 years of age.

Conclusions

This is an opportune moment to re-examine the role and place of BMR measurements in estimating total energy requirements today. The Oxford equations' future use and application will surely depend on their ability to predict more accurately the BMR in contemporary populations.

Keywords

Universal validityBasal metabolic rateEnergy metabolismEnergy requirementsBody mass index
Type
Research Article
Information
Public Health Nutrition , Volume 8 , Issue 7a , October 2005 , pp. 1133 - 1152
Copyright
Copyright © The Author 2005

References

1FAO/WHO/UNU. Energy and Protein Requirements. Report of a Joint FAO/WHO/UNU Expert Consultation. Technical Report Series No. 724. Geneva: World Health Organization, 1985.Google Scholar
2Mitchell, HH. Comparative Nutrition of Man and Domestic Animals. Vol. 1. New York: Academic Press, 1964.Google Scholar
3Aub, JC, DuBois, EF. Clinical calorimetry: the basal metabolism of dwarfs and legless men with observations on the specific dynamic action of protein.Archives of Internal Medicine 1917; 19: 840–64.CrossRefGoogle Scholar
4Aub, JC, DuBois, EF. The basal metabolism of old men. Archives of Internal Medicine 1917; 19: 823–31.CrossRefGoogle Scholar
5Krogh, A. Determination of standard (basal) metabolism of patients by recording apparatus. Boston Medical Surgery Journal 1923; 189: 313–7.CrossRefGoogle Scholar
6Blaxter, K. Energy Metabolism in Animals and Man Cambridge: Cambridge University Press, 1989.Google Scholar
7DuBois, EF, Ebaugh, FG, Hardy, JD. Basal heat production and elimination of thirteen normal women at temperatures from 22–35°C. Journal of Nutrition 1952; 48: 257–93.CrossRefGoogle Scholar
8Wilkerson, JE, Raven, PB, Horvath, SM. Critical temperature of unacclimatized male Caucasians. Journal of Applied Physiology 1972; 33: 451–5.CrossRefGoogle ScholarPubMed
9Pi-Suner, J. Studies in racial metabolism: basal metabolism of the Araucanian Mapuches. American Journal of Physiology 1933; 105: 383–8.CrossRefGoogle Scholar
10Roth, P, Buckingham, PE. The criteria of a dependable basal metabolism report. American Journal of Clinical Pathology 1939; 9: 79–92.CrossRefGoogle Scholar
11Harris, JA, Benedict, FG. A Biometric Study of Basal Metabolism in Man. Publication No. 279. Washington: Carnegie Institute of Washington, 1919.Google Scholar
12Bedale, EM. Energy expenditure and food requirements of children at school. Proceedings of the Royal Society of London 1923; 94: 368–404.Google Scholar
13FAO. Calorie Requirements. Report of the Second Committee on Calorie Requirements. Nutritional Studies No. 15. Rome: Food and Agriculture Organization, 1957.Google Scholar
14Roth, PR. Portable respiration apparatus for clinical use. Boston Medical Surgery Journal 1922; 186: 457.CrossRefGoogle Scholar
15Boothby, WM, Berkson, J, Dunn, HL. Studies of the energy metabolism of normal individuals: a standard for basal metabolism, with a nomogram for clinical application. American Journal of Physiology 1936; 116: 468–84.CrossRefGoogle Scholar
16Durnin, JVGA. Basal Metabolic Rate in Man. Working paper submitted to the Joint FAO/WHO/UNU Expert Consultation on Energy and Protein Requirements. Rome: Food and Agriculture Organization, 1981.Google Scholar
17Krogh, A. Respiratory Exchange of Animals and Man. New York: Longmans, 1916.Google Scholar
18Benedict, FG. Portable respiration apparatus for clinical use. Boston Medical Surgery Journal 1918; 178: 667.CrossRefGoogle Scholar
19Lewis, RC, Iliff, A, Duval, AM. Further consideration of the effect of altitude on basal metabolism. The Journal of Nutrition 1943; 26: 175–85.CrossRefGoogle Scholar
20Lewis, RC, Iliff, A, Duval, AM. The comparative accuracy of the closed circuit bedside method and the open circuit chamber procedure for the determination of basal metabolism. Journal of Laboratory Clinical Medicine 1943; 28: 1238–45.Google Scholar
21Lewis, RC, Duval, AM, Iliff, A. Standards for the basal metabolism of children from 2 to 15 years of age, inclusive. Journal of Pediatrics 1943; 23: 1–18.CrossRefGoogle Scholar
22Willard, HN, Wolf, GA Jr. A source of error in the determination of basal metabolism by the closed-circuit technique. Annual International Medicine 1951; 34: 148–62.Google Scholar
23Segal, KR. Comparison of indirect calorimetric measurement of resting energy expenditure with a ventilated hood, face mask, and mouthpiece. American Journal of Clinical Nutrition 1987; 45: 1420–3.CrossRefGoogle ScholarPubMed
24Shetty, PS, Soares, MJ, Sheela, ML. Basal Metabolic Rates of South Indian Males. Bangalore: Food and Agriculture Organization, 1986.Google Scholar
25Soares, MJ, Sheela, ML, Kurpad, AV, Kulkarni, RN, Shetty, PS. The influence of different methods on basal metabolic rate measurements in human subjects. American Journal of Clinical Nutrition 1989; 50: 731–6.CrossRefGoogle ScholarPubMed
26Consolazio, CF, Johnson, RE, Pecora, LJ. Physiological Measurements of Metabolic Function in Man. New York: McGraw-Hill, 1963.Google Scholar
27Clark, HD, Hoffer, LF. Reappraisal of the resting metabolic rate of normal young men. American Journal of Clinical Nutrition 1991; 53: 21–6.CrossRefGoogle ScholarPubMed
28Fowler, WS, Blackburn, CM, Helmholz, HF Jr. Determination of basal rate of oxygen consumption by open and closed-circuit methods. Journal of Clinical Endocrinological Metabolism 1957; 17: 786–96.CrossRefGoogle ScholarPubMed
29Schofield, WN, Schofield, C, James, WPT. Basal metabolic rate – review and prediction, together with an annotated bibliography of source material. Human Nutrition Clinical Nutrition 1985; 39C: 5–96.Google Scholar
30DuBois, D, DuBois, EF. The measurements of the surface area of man. Archives of Internal Medicine 1915; 15: 868–75.CrossRefGoogle Scholar
31Daly, JM, Heymsfield, SB, Head, CA, Harvey, LP, Nixon, DW, Katzeff, H, Grossman, GD. Human energy requirements: over estimation by widely used prediction equation. The American Journal of Clinical Nutrition 1985; 42: 1170–4.CrossRefGoogle Scholar
32Alpers, PH, Stevenson, WF, Bier, DM. Manual of Nutritional Therapeutics Philadelphia, Lippincott Williams and Wilkins, 1995.Google Scholar
33Boothby, WM, Sandiford, I. A comparison of the DuBois and the Harris and Benedict normal standards for the estimation of basal metabolic rate. Journal of Biological Chemistry 1922; 54: 767–81.CrossRefGoogle Scholar
34Boothby, WM, Sandiford, I. Summary of the basal metabolic data on 8614 subjects with special reference to the normal standards for the estimation of the basal metabolic rate. Journal of Biological Chemistry 1922; 54: 783–803.CrossRefGoogle Scholar
35Quenouille, MH, Boyne, AW, Fisher, WB, Leitch, I. Statistical Studies of Recorded Energy Expenditure of Man. Basal Metabolism Related to Sex, Stature, Age, Climate, and Race. Commonwealth Bureau of Animal Nutrition. Technical Communication No. 17. Aberdeen: Commonwealth Agricultural Bureau, 1951.Google Scholar
36de Almeida, AO. L'emission de chaleur. Le metabolisme basal et le metabolisme mimimum de l'homme noir tropical. Journal de Physiologie et Pathologie General 1921; 18: 958–64.Google Scholar
37Henry, CJK, Rees, DG. New predictive equations for the estimation of basal metabolic rate in tropical peoples. European Journal of Clinical Nutrition 1991; 45: 177–85.Google Scholar
38de Boer, JO, van Es, AJH, Voorrips, LE, Blockstra, F, Vogt, JE. Energy metabolism and requirements in different ethnic groups. European Journal Clinical Nutrition 1988; 42: 983–97.Google ScholarPubMed
39Arciero, PJ, Goran, MI, Gardner, AM, Ades, PA, Tyzbir, RS, Poehlman, ET. A practical equation to predict resting metabolic rate in older females. Journal of American Geriatric Society 1993; 41: 389–95.CrossRefGoogle ScholarPubMed
40Piers, LS, Shetty, PS. Basal metabolic rates of Indian women. European Journal of Clinical Nutrition 1993; 47: 586–91.Google ScholarPubMed
41Hayter, JE, Henry, CJK. A re-examination of basal metabolic rate predictive equations: the importance of geographic origin of subjects in sample selection. European Journal of Clinical Nutrition 1994; 48: 702–7.Google Scholar
42Valencia, ME, Moya, SY, McNeill, G, Haggarty, P. Basal metabolic rate and body fatness of adult men in northern Mexico. European Journal Clinical Nutrition 1994; 48: 205–11.Google ScholarPubMed
43Wong, WW, Butte, NF, Hergenroeder, AC, Hill, RB, Stuff, JE, Smith, EO. Are basal metabolic rate prediction equations appropriate for female children and adolescents? Journal of Applied Physiology 1996; 81: 2407–14.CrossRefGoogle ScholarPubMed
44Soares, MJ, Francis, DG, Shetty, PS. Predictive equations for basal metabolic rates of Indian males. European Journal of Clinical Nutrition 1993; 47: 389–94.Google ScholarPubMed
45Cruz, CM, daSilva, AF, dos Anjos, LA. A taxa metabica basal e superestimade pelas equa co es preditivas em universitaras do Rio de Janeiro, Brasil. Archivio Latino americano Nutricion 1999; 49: 232–7.Google Scholar
46Dietz, WH, Bandini, LG, Schoeller, DA. Estimates of metabolic rate in obese and non-obese adolescents. Journal of Pediatrics 1991; 118: 140–9.CrossRefGoogle Scholar
47Cunningham, JJ. A reanalysis of the factors influencing basal metabolic rate in normal adults. American Journal of Clinical Nutrition 1980; 33: 2372–3374.CrossRefGoogle ScholarPubMed
48Cunningham, JJ. Body composition as a determinant of energy expenditure: a synthetic review and a proposed general prediction equation. American Journal of Clinical Nutrition 1991; 54: 963–9.CrossRefGoogle Scholar
49Hayter, J, Henry, CJK. Basal metabolic rate in human subjects migrating between tropical and temperate regions – a longitudinal study and review of previous work. European Journal of Clinical Nutrition 1993; 47: 724–34.Google Scholar
50Ho, Z-C, Zi, HM, Bo, L, Ping, H. Energy expenditure of pre school children in a subtropical area. World Reviews in Nutrition Dietetics 1988; 57: 75–94.CrossRefGoogle Scholar
51Min, Q, Ho, Z-C. The basal metabolism rate of adolescent girls in the sub-tropical areas of China. Acta Nutrimenta Sinica 1991; 13: 252–8.Google Scholar
52Spurr, GB, Reina, JC, Hoffmann, RG. Basal metabolic rate of Colombian children 2–16 years of age: ethnicity and nutritional status. American Journal of Clinical Nutrition 1992; 56: 623–9.Google Scholar
53Torun, B, Davies, PSW, Livingstone, MBE, Paolisso, M, Sackett, R, Spurr, GB. Energy requirements and dietary energy recommendations for children and adolescents 1 to 18 years old. European Journal of Clinical Nutrition 1996; 50(Suppl. 1): S37–S81.Google Scholar
54Livingstone, MBE, Coward, WA, Prentice, AM, Davies, PSW, Strain, JJ, McKenna, PG, Mahoney, CA, White, JA, Stewart, CM, Kerr, MJJ. Daily energy expenditure in free living children: comparison of heart-rate monitoring with the doubly labelled water (2H218O) method. American Journal of Clinical Nutrition 1992; 56: 343–52.CrossRefGoogle Scholar
55Bandini, LG, Schoeller, DA, Dietz, WH Jr. Energy expenditure in obese and non-obese adolescents. Pediatric Research 1990; 27: 198–203.CrossRefGoogle Scholar
56Case, KO, Brahler, CJ, Heiss, C. Resting energy expenditures in Asian women measured by indirect calorimetry are lower than expenditures calculated from prediction equations. Journal of American Dietetic Association 1997; 97: 1288–92.CrossRefGoogle ScholarPubMed
57Leung, R, Woo, J, Chan, D, Tang, N. Validation of prediction equations for basal metabolic rate in Chinese subjects. European Journal of Clinical Nutrition 2000; 54: 551–4.CrossRefGoogle ScholarPubMed
58Piers, LS, Diffey, B, Soares, MJ, Frandsen, SL, McCormack, LM, Lutschini, MJ, O'Dea, K. The validity of predicting the basal metabolic rate of young Australian men and women. European Journal of Clinical Nutrition 1997; 51: 333–7.Google Scholar
59Ferro-Luzzi, A, Petracchi, C, Kuriyan, R, Kurpad, AV. Basal metabolism of weight-stable chronically undernourished men and women: lack of metabolic adaptation and ethnic differences. American Journal of Clinical Nutrition 1997; 66: 1086–93.CrossRefGoogle ScholarPubMed
60Yamauchi, T, Ohtsuka, R. Basal metabolic rate and energy costs at rest and during exercise in rural- and urban-dwelling Papua New Guinea Highlanders. European Journal of Clinical Nutrition 2000; 54: 494–9.CrossRefGoogle ScholarPubMed
61Norgan, NG. Population differences in body composition in relation to the Body Mass Index. European Journal of Clinical Nutrition 1994; 48(Suppl. 3) S10–S27.Google ScholarPubMed
62Shetty, PS, Henry, CJK, Black, AE, Prentice, AM. Energy requirements of adults: an update on basal metabolic rates (BMRs) and physical activity levels (PALs). European Journal of Clinical Nutrition 1996; 50(Suppl. 1): S11–S23.Google ScholarPubMed
63Hayter, J, Henry, CJK. Basal metabolic rate in human subjects migrating between tropical and temperate regions – a longitudinal study and review of previous work. European Journal of Clinical Nutrition 1993; 47: 724–34.Google ScholarPubMed
64Poehlman, ET, Melby, CL, Badylak, SF. Resting metabolic rate and post-prandial thermogenesis in highly trained and untrained males. American Journal of Clinical Nutrition 1988; 47: 793–8.CrossRefGoogle Scholar
65Robertson, JD, Reid, DD. Standards for the basal metabolism of normal people in Britain. The Lancet 1952; 1: 940–9.CrossRefGoogle ScholarPubMed
66Benedict, FG, Garven, HSD. The basal metabolism of male Chinese in Manchuria. Chinese Journal of Physiology 1936; 10: 141–8.Google Scholar
67Benedict, FG, Meyer, MH. The basal metabolism of American-born Chinese girls. Chinese Journal of Physiology 1933; 7: 45–60.Google Scholar
68Benedict, FG, Miles, WR, Roth, P, Monmouth Smith, H. Human Vitality and Efficiency Under Prolonged Restricted Diet. Washington: Carnegie Institution of Washington, 1919, 280.Google Scholar
69Benedict, FG, Talbot, FB. The Gaseous Metabolism of Infants. Washington: Carnegie Institution of Washington, 1914, 201.Google Scholar
70Benedict, FG. Age and basal metabolism of adults. Journal of Biological Chemistry 1928; 80: 650–64.Google Scholar
71Benedict, FG. Basal metabolism data on normal men and women (series II) with some considerations on the use of prediction standards. Journal of Biological Chemistry 1928; 8: 607–20.Google Scholar
72Benedict, FG. Factors affecting basal metabolism. Journal of Biological Chemistry 1915; 20: 263–99.Google Scholar
73Benedict, FG. Metabolism and Growth from Birth to Puberty. Washington: Carnegie Institution of Washington, 1921, 302.Google Scholar
74Benedict, FG. Old age and basal metabolism. New England Journal of Medicine 1935; 212: 1111–23.Google Scholar
75Benedict, FG. The basal metabolism of girls 12 to 17 years of age. Proceedings of the National Academy of Science 1921; 10–13.Google Scholar
76Lewis, RC, Kinsman, GM, Iliff, A. The basal metabolism of normal boys and girls from two to twelve years old, inclusive. American Journal of Diseases in Childhood 1937; 53: 348–428.Google Scholar
77Lewis, WH. Changes with age in the basal metabolic rate in adult men. American Journal of Physiology 1934; 12: 502–17.Google Scholar
78Mason, ED, Benedict, FG. The basal metabolism of South Indian Women. Independent Journal of Medical Research 1931; 19: 75–98.Google Scholar
79Mason, ED, Benedict, FG. The effect of sleep on human basal metabolism, with particular reference to South Indian women. American Journal of Physiology 1934; 108: 377–83.Google Scholar
80Mason, ED, Jacob, M. Variations in basal metabolic rate: responses to changes between tropical and temperate climates. Human Biology 1972; 44: 141–72.Google Scholar
81Mason, ED. The basal metabolism of European women in South India and the effect of change of climate on European and South Indian Women. Journal of Nutrition 1934; 8: 695–713.CrossRefGoogle Scholar
82Nakagawa, I. Growth and basal metabolism. Basal metabolism of preschool children. American Journal of Diseases in Childhood 1934; 47: 963–9.CrossRefGoogle Scholar
83Nakagawa, I. Growth and basal metabolism. Basal metabolism of elementary school children. American Journal of Diseases in Childhood 1934; 48: 34–8.Google Scholar
84Nakagawa, I. Growth and basal metabolism. Changes in the basal metabolism of children during a year. American Journal of Diseases in Childhood 1935; 49: 1232–9.CrossRefGoogle Scholar
85Nakagawa, I. Growth and basal metabolism. Basal metabolism of high school children. American Journal of Diseases in Childhood 1937; 51: 985–9.CrossRefGoogle Scholar
86Wardlaw, HSH, Davies, HW, Joseph, MR. Energy metabolism and insensible perspiration of Australian Aborigines. Australian Journal of Experimental Biology 1934; 12: 63–73.Google Scholar
87Wardlaw, HSH, Horsley, CH. The basal metabolism of some Australian Aborigines. Australian Journal of Experimental Biology 1928; 5: 263–72.Google Scholar
88Wardlaw, HSH, Lawrence, WJ. Further observations on the basal metabolism of Australian Aborigines. Australian Journal of Experimental Biology 1932; 10: 157–65.CrossRefGoogle Scholar
89Wang, CC, Hawks, JE. Basal metabolism of twenty-one Chinese children reared or born and reared in the United States. American Journal of Diseases in Childhood 1932; 44: 69–80.Google Scholar
90Wang, CC, Kaucher, M, Wing, M. Metabolism of adolescent girls. Basal metabolism and energy exchange. American Journal of Diseases in Childhood 1936; 51: 801–15.Google Scholar
91Wang, CC, Kern, R, Frank, M, Hays, BB. Metabolism of undernourished children. Basal metabolism. American Journal of Diseases in Childhood 1926; 32: 350–9.CrossRefGoogle Scholar
92Wang, CC. Basal metabolism and preformed total creatinine in urine of seventy children. American Journal of Diseases in Childhood 1939; 57: 838–50.Google Scholar
93Wang, CC. Basal metabolism of American-born Chinese girls and of American girls of the same age. American Journal of Diseases in Childhood 1934; 48: 1041.Google Scholar
94Holland, B, Welch, AA, Unwin, ID, Buss, DH, Paul, AA, Southgate, DAT. McCance and Widdowson's the Composition of Foods, 5th edn. Cambridge: Royal Society of Chemistry, 1991.Google Scholar