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Endocrine control of calcium and magnesium metabolism in ruminants
Published online by Cambridge University Press: 24 January 2017
Extract
Although the importance of calcium and magnesium homoeostasis has been recognized for many years the precise mechanisms by which this is achieved are still not clearly understood. Over recent years interest in blood calcium regulation has been stimulated by the discovery, isolation and synthesis of calcitonin. Its significance in normal adults, however, remains in some doubt (vide infra). In this paper is outlined our present knowledge of the endocrine factors which help to regulate the control of plasma calcium and magnesium concentration in ruminants through the operation of negative feedback mechanisms. Mention will also be made of those hormones which, although capable of altering the plasma concentrations of either calcium or magnesium, are secreted independently of these concentrations. It will be seen that in many instances the chemical similarity between calcium and magnesium is reflected in hormone effects or in hormone secretion rates. However, this is not always found to be so, e.g. the control of calcitonin secretion appears to be affected in different directions by plasma calcium and magnesium concentrations.
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- Copyright © Proceedings of the Nutrition Society 1969
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