Background :The profile of “frequent visitors” at the psychiatric emergencies (PE) has not been sufficiently investigated in Greece.

In this study we aimed to investigate the prevalence and relevant parameters of frequent PE visits in a Greek University Psychiatric Hospital for the year 2017.

In a retrospective study, we analyzed data of patients who presented in the PE of Eginition University Hospital in Athens during 2017. Frequent visitors were grouped under this category if they had at least five visits per year. Clinical and sociodemographic data of the patients were further related to number of visits.

84 patients were characterized as frequent visitors carrying out 9.8% of the total number of visits. 50% were women and 70% of them were living with family members. Anxiety, depressive and psychotic symptoms were the most frequent major complaints at the time of their visit, whereas psychosocial problems were associated with increased number of visits. Moreover, in terms of the underlying diagnosis substance use disorders significantly related to more frequent visits

Psychosocial problems and the diagnosis of substance use disorders significantly correlated to the number of visits at the PE of a university hospital setting in Greece for 2017.

No significant relationships.

Professionals in the inpatient care of burdened children and adolescents are confronted with high demands in their daily work. The job satisfaction can be affected negatively, if these professionals do not have the necessary resources to carry out their work.

In a study as part of the accompanying research of an online course called “Trauma informed Care”, the connection between the personal resources action competence, emotional competence, self-efficacy and self-care and job satisfaction were investigated on a sample of N = 543 professionals working in the (inpatient) care of children and adolescents.

In order to quantify the connections between the personal resources action competence, emotional competence, self-efficacy and self-care and job satisfaction, correlations and a multiple regression were calculated.

Moderate to strong correlations were identified between personal resources and job satisfaction among the professionals. The regression model revealed self-efficacy to be the most important predictor of job satisfaction. Self-care was also identified as an important predictor. Less importance could be ascribed to emotional competence. Action competence showed no effects in the regression model.

The results indicate the importance of personal resources for job satisfaction an their targeted promotion in order to increase job satisfaction and thus counteract the tendency of fluctuation and shortage of professionals in the area of child and youth welfare.

No significant relationships.

Being a victim of work-related upper extremity injuries is a source of physical damage and mental damages. Psychological distress related to this type of accident is usually underestimated.

Evaluate anxiety and depression among victims of work-related upper extremity injuries.

We conducted a 10-month cross-sectional analysis on workers consulting for an Impairment Rating Evaluation after an upper extremity injury due to an occupational accident. We collected socio-professional data, characteristics and outcomes of the accident. Anxiety and depression were evaluated by the Hospital Anxiety and Depression scale. The pain was evaluated by a Visual Analogue Scale.

Our population consisted of 90 cases of work-related upper-extremity injuries. The mean age was 43.10 and the sex ratio 3.7. The most represented category was blue-collar workers (71.1%). Medical history of chronic diseases was reported in 23% of cases and 3.3 % had mental health antecedent. Dominant upper limb injuries were found in 62% of cases. Hand and wrist injuries were the most affected part (63%), and 33.3% had fingers’ injuries. The prevalence of anxiety and depression were 31.1% and 20% respectively. About thirty-one per cent rated their current pain greater than or equal to 8. Both anxiety and depression were positively correlated with male gender (p= 0.001, p=0.007) and shoulder injuries (p=0.001, p=0.018). Depression was correlated to fingers’ injuries and pain (p=0.002).

The studied population present an important rate of anxiety and depression. Assessing Mental health after upper extremities injuries are necessary to prevent serious mental illness and to promote a successful return to work.

No significant relationships.

It has been broadly anticipated that COVID-19 pandemic-related experiences may constitute traumatic stressors in vulnerable populations, and that older adults’ might be especially at risk of experiencing mental health symptoms during the pandemic.

The present study aimed to examine older adults’ psychological distress: posttraumatic stress, Covid-related fears, anxiety, and depression during the pandemic, and the relationship between present distress, defensive functioning, and childhood trauma. We also explored potential differences between younger-older adults (between 65 and 74 years), and older-older adults (75 years and above).

Data was collected in a large-scale online survey during the early months of the pandemic, for the present study, we included participants above 65 years old (N = 1,225).

showed that age, adverse childhood experiences, and overall defensive functioning were all significantly related to posttraumatic stress, anxiety, and depression. Specifically, younger age and more reported childhood adversity were related to higher distress, whereas higher defensive functioning was related to less distress. Covid-related fears were not associated with age. Our final model showed that defensive functioning mediated the relationship between childhood trauma and distress.

Our results support the relative resilience of older-older adults compared to younger-older adults, as well as the long-lasting impact of childhood adversity through defensive functioning later in life, specifically in times of heightened stress, such as the COVID-19 pandemic. Future studies are warranted to identify further factors affecting defensive functioning as adults age, as well as processes that are associated with resilience in response to stressors in older adulthood.

No significant relationships.

Despite the large amount of research concerning the impact of COVID-19 on health care workers, to date few targeted MHWs. Moreover, none has investigated the vulnerability due to exposure to previous traumatic events among health care workers.

This study aimed to investigate the psychological distress in MHWs after the first lockdown imposed by the COVID-19 pandemic in the more impacted regions of the North of Italy, to understand which COVID-19, sociodemographic and professional variables as well as previous stressful life experiences, could have had greater negative effects.

The online survey occurred from 28-June to 10-August 2020. This included questions regarding sociodemographic factors, professional information, COVID-19 exposure. Moreover, three validated self-report questionnaires were administered: Life Events Checklist for DSM-5 (LEC-5), Impact of Event Scale-Revised (IES-R), Depression Anxiety Stress Scales-21 (DASS-21).

271 MHWs completed the survey. At least 20% had elevated levels of psychological distress with post-traumatic symptoms. Stratifying for professional roles, the nurses resulted the most affected, with significantly higher scores in terms of intrusive thoughts, hyperarousal and avoidance behaviors. Several variables affected psychological distress in MHWs, but stronger effects were done by age, professional roles, increased workload and worst working environment during COVID-19 pandemic, to had experienced the separation of family members, but also had experienced during their life of a severe human suffering (physical and/or psychological) on oneself or on a loved one.

Our data underlying the importance of recent but also previous severe stressful events as risk factors to develop post-traumatic symptoms reducing the resilience of the subjects investigated.

No significant relationships.

Studies assessing the psychological impact of COVID-19 have shown that patients with COVID-19 had significantly higher levels of depression, anxiety, and post-traumatic stress symptoms than healthy controls.

The objectives of our study were to assess dysfunctional anxiety in women recovered from COVID-19 and to compare it to healthy controls.

This is a cross-sectional case-control study.

We randomly recruited women, from April 1st to 30th, 2021.The women in the case group have been infected with Sars-Cov 2, with a benign or pauci-symptomatic clinical form, and cured for one to two months at the time of the study without any post-COVID complications. Women included in the control group have not been infected with Sars-Cov 2 .Anxiety was assessed by the Coronavirus Anxiety Scale (CAS).

In total, we recruited 30 women in the case group and 30 women in the control group.The average age of the case group was 35.8 ±6.8 years versus an average age of 35.3 ± 6.33 years in the control group. The majority of coronavirus infections were symptomatic (83.3% (n=25)). Nearly one-third of the patients in the case group had a CAS score greater than 9, indicating dysfunctional anxiety probably related to coronavirus (33.3%), with a significant difference with the control group (p=0.026).

COVID-19 is significantly associated with dysfunctional anxiety, even in mild or pauci-symptomatic clinical forms.

No significant relationships.

While several studies have assessed the impact of the COVID-19 pandemic on sexuality and sexual behavior in the general population, very few studies have assessed sexuality after Sars-Cov 2 infection.

The objective of our study were to assess sexuality in women recovered from COVID-19 and to compare it to healthy controls.

This is a cross-sectional case-control study.

We randomly recruited women, from April 1st to 30th, 2021.The women in the case group have been infected with Sars-Cov 2, with a benign or pauci-symptomatic clinical form, and cured for one to two months at the time of the study without any post-COVID complications. Women included in the control group have not been infected with Sars-Cov 2. Sexuality was assessed by the Female Sexual Function Index (FSFI).

In total, we recruited 30 women in the case group and 30 women in the control group.The average age of the case group was 35.8 ±6.8 years versus an average age of 35.3 ± 6.33 years in the control group. The majority of coronavirus infections were symptomatic (83.3% (n=25)). An FSFI score <26.55 and corresponding to impaired sexual function was found in 63.33% of women in the case group (n=19), versus 53.33% of women in the control group (n=16) with a significant difference between the two groups (p=0.009)

COVID-19 is significantly associated with sexual dysfunction, even in mild or pauci-symptomatic clinical forms.

No significant relationships.

The COVID-19 pandemic has several risks particularly in the elderly, such a high death rate and severe forms.The risk also involves significant psychological distress especially anxiety.

Assessment of anxiety symptoms due to COVID 19 in elderly subjects in Tunisia.

A cross-sectional descriptive study on a sample of 50 people aged between 65 and over. Data was collected using a questionnaire and a COVID Anxiety Rating Scale “Fear of COVID-19 Scale”.

We found that most subjects agreed or strongly agreed that they were afraid of Corona and that 54% agreed or strongly agreed that they felt uncomfortable thinking about the Corona. Physical symptoms like having sweaty hands, or having palpitations related to the fear of having the disease were reported by 24% of the subjects. Almost half of the respondents (46%) were afraid of losing their lives due to Corona. Most subjects (66%) reported that they became nervous or anxious when viewing information posted on social media on Corona. Insomnia related to worries about having COVID was reported in 12% of subjects. We were able to retain that most of the subjects (68%) had a mild level of anxiety and that 30% of the subjects had a moderate level. No subject had severe anxiety.

Low to moderate level of fear due to the COVID 19 pandemic was observed among Tunisian elderly according to this study. This leads us to conclude that assessment of anxiety particularly in seniors should be more systematic.

No significant relationships.

Adolescents have to cope with several challenges and restrictions due to the COVID-19 pandemic, with many of those incongruent with the typical developmental tasks of adolescent age. Some adolescent might be particularly vulnerable in this situation.

This study aimed: 1) to collect data on the mental health and quality of life of adolescents during/after the pandemic; 2. to improve adolescents’ mental health by providing an online prevention program that addresses their actual needs; 3. to accelerate the development of culturally adapted prevention programs by involving an international team, and 4. to contribute to adequate preparation for any similar situation in the future.

Participants aged 11-18 years and their parents/caregivers were recruited online. Data has been collected regularly in a follow-up study by Inventar zur Erfassung der Lebensqualitat and Strengths and Difficulties Questionnaire. The baseline data collection was in March 2020 at first restrictions of the COVID pandemic in Europe

In the baseline data 428 adolescents (29.7% boys;70.3% girls) were included. Adolescents reported significantly lower quality of life during the pandemic (F (1,557) = 29.11; p <0.001; R2 = 0.048). There was no significant difference in quality of life according to whether the adolescents live in a household with their siblings ( F (2, 356) = 0.785 p = 0.457; η2 = 0.004), and whether the adolescents have symptoms of hyperactivity (ß = 0.105; p = 0.295).

Prevention based on the results of this study is expected to contribute to maintaining adolescents’ mental health during and after the COVID pandemic.

No significant relationships.

Facing the COVID-19 pandemic, individuals are experiencing severe mental distress. Following social distancing and economic insecurity, significant increases in mental health concerns have developed.

The aims of this study was to report the levels of depressive and anxiety within active population in Romania, and to identify possible risk and protective factors for mental health.

Data collection occurred between February-March 2021. The online survey included questions regarding socio-demographic characteristics and Hospital Anxiety and Depression Scale (HADS). 620 responses were validated (331 students and 289 workers).

Among active population, risk of anxiety symptoms is lower in those who already were infected with SARS-Cov2 (p=0.026, df=2, Phi=0.109), while positive screening for anxiety or depression in this study was statistically significant associated with younger age (p=0.026, df=4, Phi=0.134) and female gender (p=<0.001, df=2, Phi=0.166). Even though anxiety and depression scores are similar among students and employees, there are different aspects regarding symptomatology between these two groups. Students have experienced more frequently tendency to worry and sudden feelings of panic (p=0.004, df=3, Phi=0.146). Also, their ability to laugh and see the funny side of things is affected (p=0.019, df=3, Phi=0.127) and they feel less enthusiasm about future (p=0.001, df=3, Phi=0.159). Participants living with someone else scored lower on anxiety and depression subscales and those are not influenced by the person with whom they are cohabitating or residing (p=0.020, df=3, Phi=0.138).

Findings from the current study offer initial insights into the rates of anxiety and depression within active population in Romania, one year after the onset of the COVID-19 pandemic.

No significant relationships.

Timely and accurate information is foundational to moderating and curing the COVID-19 for both the public and the scientific community, while repeated media exposure to crisis-related information raises stress and anxiety among general population.

The main goal of the current study was to evaluate the associations between the COVID-19-related information sources and anxiety levels.

An online web-survey recruited participants who were ≥18 years old and lived in Romanian through an online campaign in May 2021. Participants were asked whether they received COVID-19-related information frequently from the following sources: the Internet, traditional media, medical staff in health care settings or from friends, co-workers, or family members. We also assessed participants’ level of anxiety with Zung Self-Rating Anxiety Scale (SAS) and the cut-off point for anxiety index was set at 45. The associations of each information source with anxiety were examined using multiple regression analyses to control for sex, age, education and other demographic characteristics.

In total, the data of 1559 respondents (1224 female; mean age = 37.03 years and standard deviation (SD)=12.90 years) were analysed. The mean index score for SAS were 44.28 (SD=10.6). The major source of information on COVID-19 was the Internet (59.20%) and medical stuff (58.27%), almost in equal measure, followed by traditional media (48.17%) and friends, co-workers, and family members (30.72%).

Receiving COVID-19 information from the Internet and traditional media was positively correlated with anxiety level (p=0.01), while receiving COVID-19 information from medical-stuff was associated with low levels of anxiety (p=0.03).

No significant relationships.

With the COVID-19 pandemic recognized as a major threat to human health, promoting vaccination is of paramount importance to public health.

To examine the association between factors of the Health Belief Model (HBM) and intentions to be vaccinated against COVID-19, when a vaccine becomes available.

A literature review has been made through PubMed database.

The HBM dimensions “perceived barriers”, “perceived benefits” and “perceived severity” were considered to be significant predictors of acceptance of vaccinations. The HBM constructs of cues to action (trust in third-party information sources), perceived severity of and susceptibility to COVID-19, and beliefs about the protection benefits of a COVID-19 vaccine, subsequently may elicit willingness to vaccinate. Individual predictors of vaccination were believing the vaccine is effective at preventing COVID-19, recalling their doctor recommending the vaccine. Common perceived barriers against vaccination included believing the vaccine could give people the virus, believing the vaccine can make individuals ill afterwards and preferring to develop immunity “naturally”. Patients who delayed and refused vaccine doses were more likely to have vaccine safety concerns and perceive fewer benefits associated with vaccines.

HBM is an effective tool for identifying facilitators and barriers to health behaviors. Health promotion should make use of the HBM, as the model provides a theoretically understanding of the dynamics that may enable the success of important health-related policy in the wake of COVID-19 and future pandemics and identifies the communication mechanisms that must be leveraged by governments and authorities in enforcing policy.

No significant relationships.

Acute Confusional Syndrome (ACS) is the most common neuropsychiatric complication in COVID-19 infection. Its management is still a challenge because the data and recommendations based on the evidence are limited.

To describe the differential characteristics in the management of ACS in patients with COVID-19 pneumonia compared to ACS secondary to other causes.

We present a descriptive study that is has been carried out in 62 patients with ACS (26 of them diagnosed with COVID 19 pneumonia), who have required assessment by the liaison psychiatry service of Hospital del Mar between February and April, 2020. The sample was divided in 2 groups (with and without COVID 19 pneumonia). Chi square and Fisher’s tests were used to comparisons.

Dexmetomidine (26 vs 0) and olanzapine (13 vs 3) were significantly more frequently used in COVID-19 patients (p< 0 001). A greater number of different antipsychotic drugs were used in COVID 19 patients (2.40± 1 323 number of drugs), (p<0.0001). Further neuroimaging tests were requested in COVID 19 patients and they received less family support (4) compared to non COVID-19 (22), (p<0.005).

ACS associated with COVID-19 pneumonia in the patients in our sample is more difficult to manage than ACS associated with other pathologies, similar to which described in other series. It is associated with a longer duration of confusional symptoms and difficulties for control it.

No significant relationships.

The various restrictions and physical distancing introduced inRussia in early months of COVID-19pandemic could have a particular impact on people who use alcohol and create new needs for prevention and treatment of associated disorders.

The study was aimed at assessing changes in alcohol consumption among users of online social networks in Russia.

During June-September 2020,1518 adult users (18+) of the most popular social networks in Russia (Odnoklassniki, VKontakte,Facebook, Twitter), completed an anonymous online survey regarding alcohol use changes in the first months of COVID-19 pandemic. Binary logistic regression was used to estimate associations of increased alcohol consumption with socio-demographic and pandemic-related factors.

35.4%of men and 25.6%of women increased their frequency of drinking; 24.9%of men and 17.7%of women increased their typical one-time volume of alcohol consumption,and 28.5% of men and 27.9% of women increased frequency of heavy episodic drinking in the early months of pandemic. After mutual adjustment of independent variables,age18-29 years(OR=1.710;95%CI 1.002-2.917), very strong restrictions of everyday life(3.127; 1.011-9.675)and severe negative consequences in relation to professional or financial situation due to spread ofSARS-CoV-2 (2.247; 1.131-4.465) were positively associated with increase in frequency of drinking. The odds of increase in frequency of heavy episodic drinking were more than twice higher(2.329; 1.001-5.428) among those who experienced severe negative consequences to their professional/financial situation.Higher typical frequency,larger one-time volume of alcohol use,and higher frequency of heavy episodic drinking before pandemic were positively associated with increase of alcohol consumption in early months of pandemic.

Timely monitoring of changes in alcohol consumption during pandemic can allow prevention of alcohol-related disorders, including mental disorders, among users of online social networks.

No significant relationships.

Most research on COVID-19 effects has focused on the general population. Here we measure its impact on Dutch FACT and autism outpatient service users during both waves.

This study aimed to: 1) investigate participants’ mental health, 2) assess experiences with outpatient services, and 3) assess respondents’ experiences with governmental measures in the Netherlands during the first and second wave of COVID-19.

Respondents (wave 1: n=100; wave 2: n=150) reported on mental health, experiences with outpatient care, government measures and information services in an online survey.

Findings demonstrate happiness was rated an average of 6 out of 10, 70% of respondents scored below average on resilience, positive consequences for mental health (ordered world, reflection time) during both waves were similar, and prominent negative consequences included decreased social interactions and increased or new problems regarding mental health and daily functioning from wave 1-2. Lifestyle changed in 50% in both waves, although only slightly attributed to the pandemic. Substance use during both waves hardly changed. Mental healthcare continuation was highly appreciated in both waves (75-80% scored ≥7 on 10-point scale). (Video)calling was the most frequently mentioned positive care experience; missing face-to-face contact with care providers considered most negative. COVID-19 measures were less doable in the second wave. Vaccination willingness approximated 70%.

Results show a nuanced, but clear picture of experiences during both waves. Continuation of services through tele-health was well-received. Monitoring of long-term impact is needed.

No significant relationships.

People with schizophrenia could be more substantially influenced by the emotional stress brought on by the COVID-19 pandemic, resulting in relapses or worsening of an already existing mental health condition because of the high susceptibility to stress.

This study aimed to assess the presence of relapse and its risk factors among patients with schizophrenia during the era of COVID 19 pandemic.

This study included 90 adults who met DSM-5 criteria for schizophrenia and were diagnosed by (SCID-I) Arabic version and who are following up at the outpatient psychiatric clinic, Zagazig University Hospital, Egypt, Positive and Negative Syndrome Scale (PANSS) measuring severity of symptoms, Compliance Rating Scale (CRS) and World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). scales were conducted on those patients before COVID-19 pandemic from January to April 2019 and repeated on September to November 2020 during COVID 19 pandemic to compare clinical parameters between those two periods as to detect any deterioration in their clinical state.

The mean score of compliance rating scale (CRS) was decreased after COVID-19 pandemic compared to before COVID 19 (P<0.001).The mean score of PANSS scale positive subscale (P) had increased after COVID-19 pandemic compared to before COVID 19 (P<0.001).

There was a deterioration of the clinical state of schizophrenic patients during COVID-19 pandemic especially the positive symptoms and following up the news about COVID-19 regularly, decreased level of family support, lower level of compliance with treatment, and having a family member with COVID-19 infection or death were the risk factors for relapse.

No significant relationships.

Vaccine hesitancy has been an ongoing complex public issue in the Philippines posing threats to progress against preventable outbreaks and significant morbidity and mortality from COVID-19. Patients with cancer were not included in the initial vaccine trials against COVID-19 hence the plausible explanation behind vaccine hesitancy in this population. This study attempts to determine the factors affecting a patient diagnosed with breast cancer to receive COVID-19 vaccine based on constructs from the Health Beliefs Model (HBM).

To determine the factors affecting a Filipino diagnosed with breast cancer to receive COVID-19 vaccine, namely; perceived susceptibility and severity to COVID-19 and perceived benefits and barriers to getting a vaccination against COVID-19.

A single- center, descriptive, cross-sectional study in patients diagnosed with breast cancer was conducted to assess COVID-19 vaccine hesitancy.

A total of 85 eligible breast cancer patients were included in the analyses. Age, socio-economic factors, and presence of co-morbidities and metastasis were not significantly associated with COVID-19 vaccine hesitancy. Concerns on efficacy, safety, faulty or fake vaccine, as well as if the vaccine was taken by many in the public were significantly associated with hesitancy (p <0.05) when taken as individual factors. The perception of COVID-19 vaccine safety under the perceived barriers construct was found to be the only significant factor to predict vaccine hesitancy (OR= 4.737, CI 1.75, 12.82).

Interventions that focus on perceived barriers are most crucial in order to increase vaccination rate among breast cancer patients.

No significant relationships.

During a public health crisis, preventive measures are essential. However, to make them effective, all citizens must be engaged.

To analyse the differential role of individual and contextual variables in the adherence to public health recommendations.

1376 adults (70.5% female; mean age=35.55±14.27) completed a survey between September/2020 and May/2021 with: Adherence Scale to the Recommendations during COVID-19 (ASR-COVID19; evaluates three dimensions of adherence), Fear of Covid-19 Scale (FC19S) and Toronto and Coimbra Prosocial Behaviour Questionnaire (ProBeQ; assesses empathy and altruism).

Adherence did not differ between individuals with or without personal or family history of COVID-19 infection. ASR-COVID19 and all dimensions were positively correlated to ProBeQ’s altruism and empathy (from r=.32 to r=.54); FCV19S correlated positively to total adherence score and house sanitation (from r=.18 to r=.26; all p<.01). Linear regressions revealed that altruism and empathy (first model), as well as fear of Covid-19 (second model), were significant predictors of adherence; however, while the first model explained ≅28% of its variance, the second (FCV19S as independent variable) only explained ≅3%. Regression models performed in a subsample of participants with personal or family history of COVID-19 revealed that only empathy, but not altruism, was a significant predictor of adherence; in this subsample, fear was no longer a significant predictor of adherence, except for lockdown and use of teleservices.

Based on our results, we suggest health care providers and public health campaigns should take into consideration social solidarity and altruism, as well as previous experiences, when appealing to public’s engagement in health behaviour.

No significant relationships.

A higher risk of mental health consequences in critical COVID-19 patients is expected due to several reasons, including prolonged mechanical ventilation with exposure to high sedation. In this context, post-discharge depression has been reported in previous COVID-19 studies, with a profound impact on patients’ health-related quality of life (HRQoL).

To identify depressive symptoms in COVID-19 survivors 1-year after hospital discharge and to analyse its association with HRQoL.

As part of the longitudinal MAPA project, this study enrolled critical COVID-19 patients admitted in the Intensive Care Medicine Department of a University Hospital (March-May 2020). Participants were assessed through telephone by an intensive care nurse and a psychologist, with the Patient Health Questionnaire (PHQ-9) (depressive symptoms), EuroQol five-dimension five-level questionnaire (EQ-5D-5L) and EQ-Visual Analogue Scale (EQ-VAS) (global health status patient record).

A sample of 55 survivors (median age=66 years; 69% males) were included, with 20% showing depressive symptoms. Pain/discomfort (67%) and anxiety/depression (67%) were the most EQ-5D-5L domains reported. Survivors scoring for depression had more problems in all HRQoL areas (mobility:91%vs.48%, p=0.015; self-care:64%vs.27%, p=0.035; usual activities:91%vs.50%, p=0.017; pain/discomfort:100%vs.59%, p=0.010; anxiety/depression:100%vs.59%, p=0.010). Moreover, they had a lower EQ-VAS median, corresponding a worse self-perception of health status (50vs.80, p=0.010).

Even after 1-year, a significant proportion of survivors presented depressive symptoms with repercussions in all HRQoL dimensions and association with worse self-perception of global quality of life. Taking this in mind, early screening and treatment of depression in COVID-19 survivors will be crucial, minimizing its impact on quality of life.

No significant relationships.

Severe COVID-19 survivors experience long-term neuropsychiatric morbidity, particularly those who developed delirium, with a negative impact on health-related quality of life (HRQoL).

To identify the cases of delirium in severe COVID-19 patients and to describe its association with post-hospital discharge HRQoL.

In the context of the longitudinal MAPA project, we included adult patients (≥ 18 years old) admitted with COVID-19 to the Intensive Care Medicine Department (ICMD) of a Portuguese University Hospital (October 2020-April 2021). Exclusion criteria were: ICMD length of stay ≤24h, terminal illness, major auditory loss, or inability to communicate at the time of assessment. Delirium during ICMD stay was ascertained based on patients’ clinical records. HRQoL was evaluated using the 5-Level EQ-5D questionnaire (EQ-5D-5L), at a scheduled telephone follow-up appointment on average 1-2 months after hospital discharge.

Overall, 124 patients were included with a median age of 62 (range: 24-86) years, being mostly male (65%). About 19% had delirium, 42% were deeply sedated and 43% required invasive mechanical ventilation. Most survivors reported problems on the EQ-5D-5L domains: usual activities (85%), mobility (73%) and anxiety/depression (65%). Patients with delirium reported more pain/discomfort (75%vs46%; p=0.011) and considerably anxiety/depression (83%vs60%; p=0.032).

These findings pointed that COVID-19 patients who experienced delirium reported worse HRQoL, regarding pain/discomfort and anxiety/depression. This study highlights the importance of not only prevention but also early screening of delirium during hospital stay, as well as the crucial role of the timely interventions at discharge, in order to minimize delirium long-term impacts.

No significant relationships.