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Depressive symptoms and health-related quality of life in critical COVID-19 survivors: Preliminary results of 1-year follow-up

Published online by Cambridge University Press:  01 September 2022

S. Martins ,
L. Fontes ,
A.R. Ferreira ,
J. Fernandes ,
T. Vieira ,
N. Reis ,
A. Braga ,
I. Coimbra ,
J.A. Paiva  and
L. Fernandes
S. Martins*
Affiliation:
Faculty of Medicine - University Porto, Department Of Clinical Neuroscience And Mental Health And Center for health technology and services research (cintesis), Porto, Portugal
L. Fontes
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
A.R. Ferreira
Affiliation:
Faculty of Medicine - University Porto, Department Of Clinical Neuroscience And Mental Health And Center for health technology and services research (cintesis), Porto, Portugal
J. Fernandes
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
T. Vieira
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
N. Reis
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
A. Braga
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
I. Coimbra
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
J.A. Paiva
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal Faculty of Medicine - University Porto, Department Of Medicine, Porto, Portugal
L. Fernandes
Affiliation:
Faculty of Medicine - University Porto, Department Of Clinical Neuroscience And Mental Health And Center for health technology and services research (cintesis), Porto, Portugal Psychiatry Service, Centro Hospitalar Universitário De São João, Porto, Portugal
*
*Corresponding author.

Abstract

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Introduction

A higher risk of mental health consequences in critical COVID-19 patients is expected due to several reasons, including prolonged mechanical ventilation with exposure to high sedation. In this context, post-discharge depression has been reported in previous COVID-19 studies, with a profound impact on patients’ health-related quality of life (HRQoL).

Objectives

To identify depressive symptoms in COVID-19 survivors 1-year after hospital discharge and to analyse its association with HRQoL.

Methods

As part of the longitudinal MAPA project, this study enrolled critical COVID-19 patients admitted in the Intensive Care Medicine Department of a University Hospital (March-May 2020). Participants were assessed through telephone by an intensive care nurse and a psychologist, with the Patient Health Questionnaire (PHQ-9) (depressive symptoms), EuroQol five-dimension five-level questionnaire (EQ-5D-5L) and EQ-Visual Analogue Scale (EQ-VAS) (global health status patient record).

Results

A sample of 55 survivors (median age=66 years; 69% males) were included, with 20% showing depressive symptoms. Pain/discomfort (67%) and anxiety/depression (67%) were the most EQ-5D-5L domains reported. Survivors scoring for depression had more problems in all HRQoL areas (mobility:91%vs.48%, p=0.015; self-care:64%vs.27%, p=0.035; usual activities:91%vs.50%, p=0.017; pain/discomfort:100%vs.59%, p=0.010; anxiety/depression:100%vs.59%, p=0.010). Moreover, they had a lower EQ-VAS median, corresponding a worse self-perception of health status (50vs.80, p=0.010).

Conclusions

Even after 1-year, a significant proportion of survivors presented depressive symptoms with repercussions in all HRQoL dimensions and association with worse self-perception of global quality of life. Taking this in mind, early screening and treatment of depression in COVID-19 survivors will be crucial, minimizing its impact on quality of life.

Disclosure

No significant relationships.

Keywords

DepressionCovid-19health-related quality of life
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S310 - S311
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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