We consider a concrete family of $2$ -towers $(\mathbb {Q}(x_n))_n$ of totally real algebraic numbers for which we prove that, for each $n$ , $\mathbb {Z}[x_n]$ is the ring of integers of $\mathbb {Q}(x_n)$ if and only if the constant term of the minimal polynomial of $x_n$ is square-free. We apply our characterization to produce new examples of monogenic number fields, which can be of arbitrary large degree under the ABC-Conjecture.