Book contents
- Rare Causes of Stroke
- Rare Causes of Stroke
- Copyright page
- Contents
- Contributors
- Preface
- 1 Inflammatory Conditions
- 2 Infectious and Postinfectious Vasculitis
- 3 Hypercoagulable Causes of Stroke
- Chapter 3.1 Antiphospholipid Antibody Syndrome
- Chapter 3.2 Hyperhomocysteinemia
- Chapter 3.3 Hyperviscosity Syndrome
- Chapter 3.4 Disseminated Intravascular Coagulation and Moschkowitz Syndrome
- Chapter 3.5 Immunoglobulin A Vasculitis (Henoch–Schönlein Purpura)
- Chapter 3.6 Stroke Associated With Cancer
- 4 Drug-Related Stroke
- 5 Hereditary and Genetic Causes of Stroke
- 6 Rare Causes of Cardioembolism
- 7 Vasospastic Conditions and Other Vasculopathies
- 8 Other Non-inflammatory Vasculopathies
- 9 Venous Occlusive Conditions
- 10 Bone Disorders and Stroke
- Index
- References
Chapter 3.5 - Immunoglobulin A Vasculitis (Henoch–Schönlein Purpura)
from 3 - Hypercoagulable Causes of Stroke
Published online by Cambridge University Press: 06 October 2022
- Rare Causes of Stroke
- Rare Causes of Stroke
- Copyright page
- Contents
- Contributors
- Preface
- 1 Inflammatory Conditions
- 2 Infectious and Postinfectious Vasculitis
- 3 Hypercoagulable Causes of Stroke
- Chapter 3.1 Antiphospholipid Antibody Syndrome
- Chapter 3.2 Hyperhomocysteinemia
- Chapter 3.3 Hyperviscosity Syndrome
- Chapter 3.4 Disseminated Intravascular Coagulation and Moschkowitz Syndrome
- Chapter 3.5 Immunoglobulin A Vasculitis (Henoch–Schönlein Purpura)
- Chapter 3.6 Stroke Associated With Cancer
- 4 Drug-Related Stroke
- 5 Hereditary and Genetic Causes of Stroke
- 6 Rare Causes of Cardioembolism
- 7 Vasospastic Conditions and Other Vasculopathies
- 8 Other Non-inflammatory Vasculopathies
- 9 Venous Occlusive Conditions
- 10 Bone Disorders and Stroke
- Index
- References
Summary
Immunoglobulin A (IgA) vasculitis, formerly called Henoch-Schönlein purpura is a nonthrombocytopenic, immune-mediated, leukocytoclastic, small vessel vasculitis. It is the most common form of systemic vasculitis in children. Adults are less frequently affected. Most studies show a male predominance. There is a seasonal pattern with rarest occurrence in summer, probably because of the association of IgA vasculitis with infections. Pathophysiologically, immune complex IgA deposition in vessel walls is leading to complement activation, which is causing vessel injury. Neurological manifestation is more frequent in other forms of vasculitis. But, neurological manifestation of IgA vasculitis is possible, but rare. They involve affection of the central and peripheral nervous system. Sokol et al. reported the case of a 15-year-old girl presenting with aphasia and right-sided weakness associated with lethargy. Diagnostic tests led to the diagnosis of IgA vasculitis with neurologic involvement
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- Rare Causes of StrokeA Handbook, pp. 174 - 178Publisher: Cambridge University PressPrint publication year: 2022