Book contents
- Frontmatter
- Contents
- List of Contributors
- Preface
- NEURODEVELOPMENTAL MECHANISMS IN PSYCHOPATHOLOGY
- Part One Basic Mechanisms in Prenatal, Perinatal, and Postnatal Neurodevelopmental Processes and Their Associations with High-Risk Conditions and Adult Mental Disorders
- 1 Principles of Neurobehavioral Teratology
- 2 The Neurodevelopmental Consequences of Very Preterm Birth: Brain Plasticity and Its Limits
- 3 Neurodevelopment During Adolescence
- 5 Prenatal Risk Factors for Schizophrenia
- 5 Obstetric Complications and Neurodevelopmental Mechanisms in Schizophrenia
- 6 Maternal Influences on Prenatal Neural Development Contributing to Schizophrenia
- Part Two Animal Models of Neurodevelopment and Psychopathology
- Part Three Models of the Nature of Genetic and Environmental Influences on the Developmental Course of Psychopathology
- Part Four The Neurodevelopmental Course of Illustrative High-Risk Conditions and Mental Disorders
- Index
- References
2 - The Neurodevelopmental Consequences of Very Preterm Birth: Brain Plasticity and Its Limits
Published online by Cambridge University Press: 10 August 2009
- Frontmatter
- Contents
- List of Contributors
- Preface
- NEURODEVELOPMENTAL MECHANISMS IN PSYCHOPATHOLOGY
- Part One Basic Mechanisms in Prenatal, Perinatal, and Postnatal Neurodevelopmental Processes and Their Associations with High-Risk Conditions and Adult Mental Disorders
- 1 Principles of Neurobehavioral Teratology
- 2 The Neurodevelopmental Consequences of Very Preterm Birth: Brain Plasticity and Its Limits
- 3 Neurodevelopment During Adolescence
- 5 Prenatal Risk Factors for Schizophrenia
- 5 Obstetric Complications and Neurodevelopmental Mechanisms in Schizophrenia
- 6 Maternal Influences on Prenatal Neural Development Contributing to Schizophrenia
- Part Two Animal Models of Neurodevelopment and Psychopathology
- Part Three Models of the Nature of Genetic and Environmental Influences on the Developmental Course of Psychopathology
- Part Four The Neurodevelopmental Course of Illustrative High-Risk Conditions and Mental Disorders
- Index
- References
Summary
In this chapter, we will discuss the long-term consequences of being born very early or very small. This issue is relevant to those interested in developmental psychopathology as this area of research emphasizes the understanding of the mechanisms underlying the development of pathology in high-risk individuals, as well as the pathways to competent adaptation despite exposure to conditions of adversity.
Studies in the United States and others have shown that rates of low birth weight increase with decreasing socioeconomic status (e.g., Paneth, 1995). At the individual level, women belonging to lower socioeconomic strata are at significantly higher risk of preterm delivery, even after controlling for other known risk factors such as weight, weight gain, alcohol and tobacco consumption, ethnicity, parity, and source of prenatal care. At the geographic level, for any defined area, the more socioeconomically disadvantaged the population, the higher the incidence of preterm delivery and low birth weight. Socio-demographic factors, such as maternal education and family income, may be related to a less favorable neuropsychological outcome in low birth weight and preterm children, as well as in normal birth weight children (Sameroff, Seifer, Barocas, Zax, & Greenspan, 1987). In addition, a considerable proportion of preterm children are treated by intensive care and sustain some brain injuries and subsequent neurological and neuropsychological impairment. However, even in the absence of major neurological deficits, preterm and low birth weight children seem to be at risk of developing a variety of cognitive and behavioral problems in childhood.
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- Neurodevelopmental Mechanisms in Psychopathology , pp. 34 - 61Publisher: Cambridge University PressPrint publication year: 2003