Neurodevelopmental Mechanisms in Psychopathology

doi:10.1017/CBO9780511546365

This volume represents a burgeoning perspective on the origins of psychopathology, one that focuses on the development of the human central nervous system. The contemporary neurodevelopmental perspective assumes that mental disorders result from etiologic factors that alter the normal course of brain development. Defined here in its broadest sense, neurodevelopment is a process that begins at conception and extends throughout the life span. We now know that it is a complex process, and that its course can be altered by a host of factors, ranging from inherited genetic liabilities to psychosocial stressors. This book features the very best thinking in the converging fields of developmental neuroscience and developmental psychopathology. The developmental window represented is broad, extending from the prenatal period through adulthood, and the authors cover a broad range of etiologic factors and a spectrum of clinical disorders. Moreover, the contributors did not hesitate to use the opportunity to hypothesize about underlying mechanisms and to speculate on research directions.

- Aa Reduce text
- Aa Enlarge text

View selected items
Save to my bookmarks
Export citations
Download PDF (zip)
Save to Kindle
Save to Dropbox
Save to Google Drive
Save content to
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to .

To save content items to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Please be advised that item(s) you selected are not available.
You are about to save
Your Kindle email address

Please provide your Kindle email.

@free.kindle.com @kindle.com (service fees apply)

By using this service, you agree that you will only keep content for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services

Page 1 of 2

First
« Prev
1
2
Next »
Last

Contents

Frontmatter
pp i-iv
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Contents
pp v-vi
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

List of Contributors
pp vii-viii
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Preface
pp ix-xii
- By Dante Cicchetti, Professor of Psychology, Psychiatry, and Pediatrics and Director of Mt. Hope Family Center, University of Rochester in New York, Elaine F. Walker, Professor of Psychology and Neuroscience, Emory University in Atlanta, Georgia
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

NEURODEVELOPMENTAL MECHANISMS IN PSYCHOPATHOLOGY
pp xiii-xiv
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Part One - Basic Mechanisms in Prenatal, Perinatal, and Postnatal Neurodevelopmental Processes and Their Associations with High-Risk Conditions and Adult Mental Disorders
pp 1-2
- By Dante Cicchetti, Professor of Psychology, Psychiatry, and Pediatrics and Director of Mt. Hope Family Center, University of Rochester in New York, Elaine F. Walker, Professor of Psychology and Neuroscience, Emory University in Atlanta, Georgia
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

1 - Principles of Neurobehavioral Teratology
pp 3-33
- By Linda C. Mayes, Yale Child Study Center, Yale University, Anna Ward, Yale Child Study, Center Yale University
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

2 - The Neurodevelopmental Consequences of Very Preterm Birth: Brain Plasticity and Its Limits
pp 34-61
- By Chiara Nosarti, Institute of Psychiatry, Kings College London, Larry Rifkin, Institute of Psychiatry, Kings College London, Robin M. Murray, Institute of Psychiatry, Kings College London
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

3 - Neurodevelopment During Adolescence
pp 62-83
- By Linda Patia Spear, Center for Developmental Psychobiology, Binghamton University
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

5 - Prenatal Risk Factors for Schizophrenia
pp 84-110
- By Alan S. Brown, Department of Psychiatry, Columbia University, Ezra S. Susser, Department of Psychiatry, Columbia University
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

5 - Obstetric Complications and Neurodevelopmental Mechanisms in Schizophrenia
pp 111-137
- By Isabelle M. Rosso, Department of Psychiatry, Harvard Medical School, Tyrone D. Cannon, Department of Psychology, University of California, Los Angeles
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

6 - Maternal Influences on Prenatal Neural Development Contributing to Schizophrenia
pp 138-152
- By Jason Schiffman, Social Science Research Institute, University of Southern California, Sarnoff A. Mednick, Social Science Research Institute, University of Southern California, Ricardo Machón, Social Science Research Institute, University of Southern California, Matti Huttunen, Social Science Research Institute, University of Southern California, Kay Thomas, Social Science Research Institute, University of Southern California, Seymour Levine, Department of Psychology, University of California-Davis
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Part Two - Animal Models of Neurodevelopment and Psychopathology
pp 153-154
- By Dante Cicchetti, Professor of Psychology, Psychiatry, and Pediatrics and Director of Mt. Hope Family Center, University of Rochester in New York, Elaine F. Walker, Professor of Psychology and Neuroscience, Emory University in Atlanta, Georgia
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

7 - On the Relevance of Prenatal Stress to Developmental Psychopathology: A Primate Model
pp 155-186
- By Mary L. Schneider, Department of Kinesiology and Psychology, University of Wisconsin – Madison, Colleen F. Moore, Department of Psychology, University of Wisconsin – Madison, Gary W. Kraemer, Department of Kinesiology, University of Wisconsin – Madison
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

8 - Nonhuman Primate Models of Developmental Psychopathology: Problems and Prospects
pp 187-214
- By Dario Maestripieri, Committee on Human Development, University of Chicago, Kim Wallen, Department of Psychology, Emory University
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

9 - Early Orbitofrontal-Limbic Dysfunction and Autism
pp 215-236
- By Jocelyne Bachevalier, Department of Neurobiology and Anatomy, University of Texas Health Science Center, Katherine A. Loveland, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Part Three - Models of the Nature of Genetic and Environmental Influences on the Developmental Course of Psychopathology
pp 237-238
- By Dante Cicchetti, Professor of Psychology, Psychiatry, and Pediatrics and Director of Mt. Hope Family Center, University of Rochester in New York, Elaine F. Walker, Professor of Psychology and Neuroscience, Emory University in Atlanta, Georgia
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

10 - Genetic Structure of Neurodevelopmental Traits: Implications for the Development (and Definition of) Psychopathology
pp 239-256
- By Richard D. Todd, Division of Child Psychiatry, Washington University School of Medicine, John N. Constantino, Department of Psychiatry, Washington University School of Medicine
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

11 - Prospects and Problems in the Search for Genetic Influences on Neurodevelopment and Psychopathology: Application to Childhood Disruptive Disorders
pp 257-292
- By Irwin D. Waldman, Department of Psychology, Emory University
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

12 - Developmental Psychoneuroimmunology: The Role of Cytokine Network Activation in the Epigenesis of Developmental Psychopathology
pp 293-323
- By Douglas A. Granger, Department of Biobehavioral Health, Pennsylvania State of University, Nancy A. Dreschel, Department of Biobehavioral Health, Pennsylvania State of University, Elizabeth A. Shirtcliff, Department of Biobehavioral Health, Pennsylvania State of University
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

13 - The Hypothalamic–Pituitary–Adrenal System (HPA) and the Development of Aggressive, Antisocial, and Substance Abuse Disorders
pp 324-344
- By Keith McBurnett, Department of Psychiatry, University of Chicago, Jean King, Department of Psychiatry, University of Massachusetts, Angela Scarpa, Department of Psychology, Virginia Polytechnic Institute
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

14 - Neuroendocrine Functioning in Maltreated Children
pp 345-365
- By Dante Cicchetti, Mt. Hope Family Center, University of Rochester
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

15 - Toward Unraveling the Premorbid Neurodevelopmental Risk for Schizophrenia
pp 366-383
- By Matcheri S. Keshavan, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

16 - Interactions of the Dopamine, Serotonin, and GABA Systems During Childhood and Adolescence: Influence of Stress on the Vulnerability for Psychopathology
pp 384-402
- By Francine M. Benes, Department of Psychiatry, Columbia University
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Part Four - The Neurodevelopmental Course of Illustrative High-Risk Conditions and Mental Disorders
pp 403-404
- By Dante Cicchetti, Professor of Psychology, Psychiatry, and Pediatrics and Director of Mt. Hope Family, Center University of Rochester in New York, Elaine F. Walker, Professor of Psychology and Neuroscience, Emory University in Atlanta, Georgia
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

17 - Neurobiology of Personality Disorders: Implications for a Neurodevelopmental Model
pp 405-427
- By Larry J. Siever, Department of Psychiatry, Mount Sinai School of Medicine, Harold W. Koenigsberg, Department of Psychiatry, Mount Sinai School of Medicine, Deidre Reynolds, Department of Psychiatry, Mount Sinai School of Medicine
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

18 - Genesis and Epigenesis of Psychopathology in Children with Depressed Mothers: Toward an Integrative Biopsychosocial Perspective
pp 428-460
- By Sherryl H. Goodman, Department of Psychology, Emory University
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

19 - The Neurobiology of Child and Adolescent Depression: Current Knowledge and Future Directions
pp 461-490
- By Joan Kaufman, Department of Psychiatry, Yale University School of Medicine, Dennis Charney, Mood and Anxiety Disorders Research Program, National Institute of Mental Health
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

20 - Psychosocial Stressors as Predisposing Factors to Affective Illness and PTSD: Potential Neurobiological Mechanisms and Theoretical Implications
pp 491-525
- By Robert M. Post, Biological Psychiatry Branch, National Institute of Mental Health, Gabriele S. Leverich, Biological Psychiatry Branch, National Institute of Mental Health, Susan R. B. Weiss, Biological Psychiatry Branch, National Institute of Mental Health, Li-Xin Zhang, Biological Psychiatry Branch, National Institute of Mental Health, Guoqiang Xing, Department of Psychiatry Uniformed Services, National Institute of Mental Health, He Li, Biological Psychiatry Branch, National Institute of Mental Health, Mark Smith, Experimental Station, DuPont, Pharmaceutical National Institute of Mental Health
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

21 - Neurohormonal Aspects of the Development of Psychotic Disorders
pp 526-544
- By Elaine F. Walker, Professor of Psychology and Neuroscience, Emory University in Atlanta, Georgia, Deborah Walder, Department of Psychology, Emory University
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation

Page 1 of 2

First
« Prev
1
2
Next »
Last

Metrics

Altmetric attention score

Total number of HTML views: 0

Total number of PDF views: 0 *

Loading metrics...

Total views: 0 *

Loading metrics...

* Views captured on Cambridge Core between #date#. This data will be updated every 24 hours.

Usage data cannot currently be displayed.

Neurodevelopmental Mechanisms in Psychopathology

This Book has been cited by the following publications. This list is generated based on data provided by Crossref.

Book description

Refine List

Actions for selected content:

Contents

Frontmatter
pp i-iv

Contents
pp v-vi

List of Contributors
pp vii-viii

Preface
pp ix-xii

NEURODEVELOPMENTAL MECHANISMS IN PSYCHOPATHOLOGY
pp xiii-xiv

Part One - Basic Mechanisms in Prenatal, Perinatal, and Postnatal Neurodevelopmental Processes and Their Associations with High-Risk Conditions and Adult Mental Disorders
pp 1-2

1 - Principles of Neurobehavioral Teratology
pp 3-33

2 - The Neurodevelopmental Consequences of Very Preterm Birth: Brain Plasticity and Its Limits
pp 34-61

3 - Neurodevelopment During Adolescence
pp 62-83

5 - Prenatal Risk Factors for Schizophrenia
pp 84-110

5 - Obstetric Complications and Neurodevelopmental Mechanisms in Schizophrenia
pp 111-137

6 - Maternal Influences on Prenatal Neural Development Contributing to Schizophrenia
pp 138-152

Part Two - Animal Models of Neurodevelopment and Psychopathology
pp 153-154

7 - On the Relevance of Prenatal Stress to Developmental Psychopathology: A Primate Model
pp 155-186

8 - Nonhuman Primate Models of Developmental Psychopathology: Problems and Prospects
pp 187-214

9 - Early Orbitofrontal-Limbic Dysfunction and Autism
pp 215-236

Part Three - Models of the Nature of Genetic and Environmental Influences on the Developmental Course of Psychopathology
pp 237-238

10 - Genetic Structure of Neurodevelopmental Traits: Implications for the Development (and Definition of) Psychopathology
pp 239-256

11 - Prospects and Problems in the Search for Genetic Influences on Neurodevelopment and Psychopathology: Application to Childhood Disruptive Disorders
pp 257-292

12 - Developmental Psychoneuroimmunology: The Role of Cytokine Network Activation in the Epigenesis of Developmental Psychopathology
pp 293-323

13 - The Hypothalamic–Pituitary–Adrenal System (HPA) and the Development of Aggressive, Antisocial, and Substance Abuse Disorders
pp 324-344

14 - Neuroendocrine Functioning in Maltreated Children
pp 345-365

15 - Toward Unraveling the Premorbid Neurodevelopmental Risk for Schizophrenia
pp 366-383

16 - Interactions of the Dopamine, Serotonin, and GABA Systems During Childhood and Adolescence: Influence of Stress on the Vulnerability for Psychopathology
pp 384-402

Part Four - The Neurodevelopmental Course of Illustrative High-Risk Conditions and Mental Disorders
pp 403-404

17 - Neurobiology of Personality Disorders: Implications for a Neurodevelopmental Model
pp 405-427

18 - Genesis and Epigenesis of Psychopathology in Children with Depressed Mothers: Toward an Integrative Biopsychosocial Perspective
pp 428-460

19 - The Neurobiology of Child and Adolescent Depression: Current Knowledge and Future Directions
pp 461-490

20 - Psychosocial Stressors as Predisposing Factors to Affective Illness and PTSD: Potential Neurobiological Mechanisms and Theoretical Implications
pp 491-525

21 - Neurohormonal Aspects of the Development of Psychotic Disorders
pp 526-544

Metrics

Altmetric attention score

Full text views

Book summary page views

Neurodevelopmental Mechanisms in Psychopathology

Book description

Refine List

Actions for selected content:

Save Search

Contents

Metrics

Altmetric attention score

Full text views

Book summary page views