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  3. Cambridge Texts in Biomedical Engineering

Cambridge Texts in Biomedical Engineering provides a forum for high quality, accessible textbooks targeted at undergraduate and graduate courses in biomedical engineering. It will cover a broad range of biomedical engineering topics from introductory texts to advanced topics including, but not limited to, biomechanics, physiology, biomedical instrumentation, imaging, signals and systems, cell engineering and bioinformatics. The series will blend theory and practice, aimed primarily at biomedical engineering students but will be suitable for broader courses in engineering, life science and medicine.

  • Managing Editors: W. Mark Saltzman, Yale University , Jay Humphrey, Yale University
  • Advisory Boards: William Hendee, Medical College of Wisconsin, Roger Kamm, Massachusetts Institute of Technology, Robert Malkin, Engineering World Health, Duke University, North Carolina, Alison Noble, University of Oxford, Nicholas Peppas, University of Texas, Austin, Bernhard Palsson, University of California, Michael Sefton, University of Toronto, George Truskey, Duke University, North Carolina, Cheng Zhu, Georgia Institute of Technology

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22 results in Cambridge Texts in Biomedical Engineering

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Biomedical Engineering for Global Health
  • Cancer, Inequity, and Technology
  • Nirmala Ramanujam, Brian Crouch
  • Published online:
    20 December 2024
    Print publication:
    21 November 2024
  • Explore the fundamentals of biomedical engineering technologies with this thought-provoking introduction, framed around modern-day global cancer inequities. Connecting engineering principles to real-world global health scenarios, this textbook introduces major technological advances in cancer care through the lens of global health inequity, discusses how promising new technologies can address this inequity, and demonstrates how novel medical technologies are adopted for real-world clinical use. It includes modular chapters designed to enable a flexible pathway through material, for students from a wide range of backgrounds; boxed discussion of contemporary issues in engineering for global health, encouraging students to explore ethical questions related to science and society; supplementary lab modules for hands-on experience in translating engineering principles into healthcare solutions; and over 200 end-of-chapter problems, targeting multiple learning outcomes to solidify student understanding. This introduction is designed to equip students with all the critical, technical, and ethical knowledge they need to excel.

Introduction to Medical Software
  • Foundations for Digital Health, Devices, and Diagnostics
  • Xenophon Papademetris, Ayesha N. Quraishi, Gregory P. Licholai
  • Published online:
    12 May 2022
    Print publication:
    05 May 2022
  • Providing a concise and accessible overview of the design, implementation and management of medical software, this textbook will equip students with a solid understanding of critical considerations for both standalone medical software (software as a medical device/SaMD) and software that is integrated into hardware devices. It includes: practical discussion of key regulatory documents and industry standards, and how these translate into concrete considerations for medical software design; detailed coverage of the medical software lifecycle process ; accessible introduction to quality and risk management systems in the context of medical software; succinct coverage of essential topics in data science, machine learning, statistics, cybersecurity, software engineering and healthcare bring readers up-to-speed; six cautionary real-world case studies illustrate the dangers of improper or careless software processes. Accompanied by online resources for instructors, this is the ideal introduction for undergraduate students in biomedical engineering, electrical engineering and computer science, junior software engineers, and digital health entrepreneurs.

Biofluid Mechanics
  • James B. Grotberg
  • Published online:
    19 November 2021
    Print publication:
    22 July 2021
  • Condensing 40 years of teaching experience, this unique textbook will provide students with an unrivalled understanding of the fundamentals of fluid mechanics, and enable them to place that understanding firmly within a biological context. Each chapter introduces, explains, and expands a core concept in biofluid mechanics, establishing a firm theoretical framework for students to build upon in further study. Practical biofluid applications, clinical correlations, and worked examples throughout the book provide real-world scenarios to help students quickly master key theoretical topics. Examples are drawn from biology, medicine, and biotechnology with applications to normal function, disease, and devices, accompanied by over 500 figures to reinforce student understanding. Featuring over 120 multicomponent end-of-chapter problems, flexible teaching pathways to enable tailor-made course structures, and extensive Matlab and Maple code examples, this is the definitive textbook for advanced undergraduate and graduate students studying a biologically-grounded course in fluid mechanics.

Principles of Biomedical Instrumentation
  • Andrew G. Webb
  • Published online:
    11 August 2019
    Print publication:
    11 January 2018
  • This accessible yet in-depth textbook describes the step-by-step processes involved in biomedical device design. Integrating microfabrication techniques, sensors and digital signal processing with key clinical applications, it covers: the measurement, amplification and digitization of physiological signals, and the removal of interfering signals; the transmission of signals from implanted sensors through the body, and the issues surrounding the powering of these sensors; networks for transferring sensitive patient data to hospitals for continuous home-monitoring systems; tests for ensuring patient safety; the cost-benefit and technological trade-offs involved in device design; and current challenges in biomedical device design. With dedicated chapters on electrocardiography, digital hearing aids and mobile health, and including numerous end-of-chapter homework problems, online solutions and additional references for extended learning, it is the ideal resource for senior undergraduate students taking courses in biomedical instrumentation and clinical technology.

Introduction to Biomaterials
  • Basic Theory with Engineering Applications
  • C. Mauli Agrawal, Joo L. Ong, Mark R. Appleford, Gopinath Mani
  • Published online:
    01 February 2019
    Print publication:
    07 November 2013
  • This succinct textbook gives students the perfect introduction to the world of biomaterials, linking the fundamental properties of metals, polymers, ceramics and natural biomaterials to the unique advantages and limitations surrounding their biomedical applications. Clinical concerns such as sterilization, surface modification, cell-biomaterial interactions, drug delivery systems and tissue engineering are discussed in detail, giving students practical insight into the real-world challenges associated with biomaterials engineering; key definitions, equations and concepts are concisely summarised alongside the text, allowing students to quickly and easily identify the most important information; and bringing together elements from across the book, the final chapter discusses modern commercial implants, challenging students to consider future industrial possibilities. Concise enough to be taught in a single semester, and requiring only a basic understanding of biology, this balanced and accessible textbook is the ideal introduction to biomaterials for students of engineering and materials science.

The Cell as a Machine
  • Michael Sheetz, Hanry Yu
  • Published online:
    06 August 2018
    Print publication:
    11 January 2018
  • This unique introductory text explains cell functions using the engineering principles of robust devices. Adopting a process-based approach to understanding cell and tissue biology, it describes the molecular and mechanical features that enable the cell to be robust in operating its various components, and explores the ways in which molecular modules respond to environmental signals to execute complex functions. The design and operation of a variety of complex functions are covered, including engineering lipid bilayers to provide fluid boundaries and mechanical controls, adjusting cell shape and forces with dynamic filament networks, and DNA packaging for information retrieval and propagation. Numerous problems, case studies and application examples help readers connect theory with practice, and solutions for instructors and videos of lectures accompany the book online. Assuming only basic mathematical knowledge, this is an invaluable resource for graduate and senior undergraduate students taking single-semester courses in cell mechanics, biophysics and cell biology.

Essential Biomaterials Science
  • David Williams
  • Published online:
    28 May 2018
    Print publication:
    17 July 2014
  • This groundbreaking single-authored textbook equips students with everything they need to know to truly understand the hugely topical field of biomaterials science, including essential background on the clinical necessity of biomaterials, relevant concepts in biology and materials science, comprehensive and up-to-date coverage of all existing clinical and experimental biomaterials, and the fundamental principles of biocompatibility. It features extensive case studies interweaved with theory, from a wide range of clinical disciplines, equipping students with a practical understanding of the phenomena and mechanisms of biomaterials performance; a whole chapter dedicated to the biomaterials industry itself, including guidance on regulations, standards and guidelines, litigation, and ethical issues to prepare students for industry; informative glossaries of key terms, engaging end-of-chapter exercises and up-to-date lists of recommended reading. Drawing on the author's forty years' experience in biomaterials, this is an indispensable resource for students studying these lifesaving technological advances.

Biomedical Engineering
  • Bridging Medicine and Technology
  • 2nd edition
  • W. Mark Saltzman
  • Published online:
    28 May 2018
    Print publication:
    21 May 2015
  • The second edition of this popular introductory undergraduate textbook uses examples, applications, and profiles of biomedical engineers to show students the relevance of the theory and how it can be used to solve real problems in human medicine. The essential molecular biology, cellular biology, and human physiology background is included for students to understand the context in which biomedical engineers work. Updates throughout highlight important advances made over recent years, including iPS cells, microRNA, nanomedicine, imaging technology, biosensors, and drug delivery systems, giving students a modern description of the various subfields of biomedical engineering. Over two hundred quantitative and qualitative exercises, many new to this edition, help consolidate learning, whilst a solutions manual, password-protected for instructors, is available online. Finally, students can enjoy an expanded set of leader profiles in biomedical engineering within the book, showcasing the broad range of career paths open to students who make biomedical engineering their calling.

Quantitative Biomedical Optics
  • Theory, Methods, and Applications
  • Irving J. Bigio, Sergio Fantini
  • Published online:
    28 May 2018
    Print publication:
    07 January 2016
  • This is the textbook and reference resource that instructors, students, and researchers in biomedical optics have been waiting for. Comprehensive and up to date, it covers a broad range of areas in biomedical optics, from light interactions at the single-photon and single-biomolecule levels, to the diffusion regime of light propagation in tissue. Subjects covered include spectroscopic techniques (fluorescence, Raman, infrared, near-infrared, and elastic scattering), imaging techniques (diffuse optical tomography, photoacoustic imaging, several forms of modern microscopy, and optical coherence tomography), and laser-tissue interactions, including optical tweezers. Topics are developed from the fundamental principles of physical science, with intuitive explanations, while rigorous mathematical formalisms of theoretical treatments are also provided. For each technique, descriptions of relevant instrumentation and examples of biomedical applications are outlined, and each chapter benefits from references and suggested resources for further reading, and exercise problems with answers to selected problems.

Biomechanics
  • Concepts and Computation
  • 2nd edition
  • Cees Oomens, Marcel Brekelmans, Sandra Loerakker, Frank Baaijens
  • Published online:
    02 February 2018
    Print publication:
    08 February 2018
  • Thoroughly revised and updated for the second edition, this comprehensive textbook integrates basic and advanced concepts of mechanics with numerical methods and biomedical applications. Coverage is expanded to include a complete introduction to vector and tensor calculus, and new or fully updated chapters on biological materials and continuum mechanics, motion, deformation and rotation, and constitutive modelling of solids and fluids. Topics such as kinematics, equilibrium, and stresses and strains are also included, as well as the mechanical behaviour of fibres and the analysis of one-dimensional continuous elastic media. Numerical solution procedures based on the Finite Element Method are presented, with accompanying MATLAB-based software and dozens of new biomedical engineering examples and exercises allowing readers to practise and improve their skills. Solutions for instructors are also available online. This is the definitive guide for both undergraduate and graduate students taking courses in biomechanics.

Problems for Biomedical Fluid Mechanics and Transport Phenomena
  • Mark Johnson, C. Ross Ethier
  • Published online:
    18 December 2013
    Print publication:
    09 December 2013
  • How does one deal with a moving control volume? What is the best way to make a complex biological transport problem tractable? Which principles need to be applied to solve a given problem? How do you know if your answer makes sense? This unique resource provides over two hundred well-tested biomedical engineering problems that can be used as classroom and homework assignments, quiz material and exam questions. Questions are drawn from a range of topics, covering fluid mechanics, mass transfer and heat transfer applications. Driven by the philosophy that mastery of biotransport is learned by practice, these problems aid students in developing the key skills of determining which principles to apply and how to apply them. Each chapter starts with basic problems and progresses to more difficult questions. Lists of material properties, governing equations and charts provided in the appendices make this a fully self-contained work. Solutions are provided online for instructors.

An Introduction to Modeling of Transport Processes
  • Applications to Biomedical Systems
  • Ashim Datta, Vineet Rakesh
  • Published online:
    05 June 2012
    Print publication:
    12 November 2009
  • Organised around problem solving, this book gently introduces the reader to computational simulation of biomedical transport processes, bridging fundamental theory with real-world applications. Using this book the reader will gain a complete foundation to the subject, starting with problem simplification, implementing it in software, through to interpreting the results, validation, and optimisation. Ten case studies, focusing on emerging areas such as thermal therapy and drug delivery, with easy to follow step-by-step instructions, provide ready-to-use templates for further applications. Solution process using the commonly used tool COMSOL Multiphysics is described in detail; useful biomedical property data and correlations are included; and background theory information is given at the end of the book for easy reference. A mixture of short and extended exercises make this book a complete course package for undergraduate and beginning graduate students in biomedical and biochemical engineering curricula, as well as a self-study guide.

Biomechanics
  • Concepts and Computation
  • Cees Oomens, Marcel Brekelmans, Frank Baaijens
  • Published online:
    05 June 2012
    Print publication:
    02 February 2009
  • This is the first textbook to integrates both general and specific topics, theoretical background and biomedical engineering applications, as well as analytical and numerical approaches. This quantitative approach integrates the classical concepts of mechanics and computational modelling techniques, in a logical progression through a wide range of fundamental biomechanics principles. Online MATLAB-based software along with examples and problems using biomedical applications will motivate undergraduate biomedical engineering students to practise and test their skills. The book covers topics such as kinematics, equilibrium, stresses and strains, and also focuses on large deformations and rotations and non-linear constitutive equations, including visco-elastic behaviour and the behaviour of long slender fibre-like structures. This is the definitive textbook for students.

Biosimulation
  • Simulation of Living Systems
  • Daniel A. Beard
  • Published online:
    05 June 2012
    Print publication:
    12 April 2012
  • This practical guide to biosimulation provides the hands-on experience needed to devise, design and analyze simulations of biophysical processes for applications in biological and biomedical sciences. Through real-world case studies and worked examples, students will develop and apply basic operations through to advanced concepts, covering a wide range of biophysical topics including chemical kinetics and thermodynamics, transport phenomena, and cellular electrophysiology. Each chapter is built around case studies in a given application area, with simulations of real biological systems developed to analyze and interpret data. Open-ended project-based exercises are provided at the end of each chapter, and with all data and computer codes available online (www.cambridge.org/biosim) students can quickly and easily run, manipulate, explore and expand on the examples inside. This hands-on guide is ideal for use on senior undergraduate/graduate courses and also as a self-study guide for anyone who needs to develop computational models of biological systems.

Numerical and Statistical Methods for Bioengineering
  • Applications in MATLAB
  • Michael R. King, Nipa A. Mody
  • Published online:
    05 June 2012
    Print publication:
    04 November 2010
  • The first MATLAB-based numerical methods textbook for bioengineers that uniquely integrates modelling concepts with statistical analysis, while maintaining a focus on enabling the user to report the error or uncertainty in their result. Between traditional numerical method topics of linear modelling concepts, nonlinear root finding, and numerical integration, chapters on hypothesis testing, data regression and probability are interweaved. A unique feature of the book is the inclusion of examples from clinical trials and bioinformatics, which are not found in other numerical methods textbooks for engineers. With a wealth of biomedical engineering examples, case studies on topical biomedical research, and the inclusion of end of chapter problems, this is a perfect core text for a one-semester undergraduate course.

Biomedical Engineering
  • Bridging Medicine and Technology
  • W. Mark Saltzman
  • Published online:
    05 June 2012
    Print publication:
    29 June 2009
  • This is an ideal text for an introduction to biomedical engineering. The book presents the basic science knowledge used by biomedical engineers at a level accessible to all students and illustrates the first steps in applying this knowledge to solve problems in human medicine. Biomedical engineering encompasses a range of fields of specialization including bioinstrumentation, bioimaging, biomechanics, biomaterials, and biomolecular engineering. This introduction to bioengineering assembles foundational resources from molecular and cellular biology and physiology and relates them to various sub-specialties of biomedical engineering. The first two parts of the book present basic information in molecular/cellular biology and human physiology; quantitative concepts are stressed in these sections. Comprehension of these basic life science principles provides the context in which biomedical engineers interact. The third part of the book introduces sub-specialties in biomedical engineering, and emphasizes - through examples and profiles of people in the field - the types of problems biomedical engineers solve.

Biomedical Engineering for Global Health
  • Rebecca Richards-Kortum
  • Published online:
    05 June 2012
    Print publication:
    29 October 2009
  • Can technology and innovation transform world health? Connecting undergraduate students with global problems, Rebecca Richards-Kortum examines the interplay between biomedical technology design and the medical, regulatory, economic, social and ethical issues surrounding global health. Driven by case studies, including cancer screening, imaging technologies, implantable devices and vaccines, students learn how the complexities and variation across the globe affect the design of devices and therapies. A wealth of learning features, including classroom activities, project assignments, homework problems and weblinks within the book and online, provide a full teaching package. For visionary general science and biomedical engineering courses, this book will inspire students to engage in solving global issues that face us all.

Chemical Biophysics
  • Quantitative Analysis of Cellular Systems
  • Daniel A. Beard, Hong Qian
  • Published online:
    05 June 2012
    Print publication:
    29 May 2008
  • Chemical Biophysics provides an engineering-based approach to biochemical system analysis for graduate-level courses on systems biology, computational bioengineering and molecular biophysics. It is the first textbook to apply rigorous physical chemistry principles to mathematical and computational modeling of biochemical systems for an interdisciplinary audience. The book is structured to show the student the basic biophysical concepts before applying this theory to computational modeling and analysis, building up to advanced topics and research. Topics explored include the kinetics of nonequilibrium open biological systems, enzyme mediated reactions, metabolic networks, biological transport processes, large-scale biochemical networks and stochastic processes in biochemical systems. End-of-chapter exercises range from confidence-building calculations to computational simulation projects.

Introductory Biomechanics
  • From Cells to Organisms
  • C. Ross Ethier, Craig A. Simmons
  • Published online:
    05 June 2012
    Print publication:
    12 March 2007
  • Introductory Biomechanics is a new, integrated text written specifically for engineering students. It provides a broad overview of this important branch of the rapidly growing field of bioengineering. A wide selection of topics is presented, ranging from the mechanics of single cells to the dynamics of human movement. No prior biological knowledge is assumed and in each chapter, the relevant anatomy and physiology are first described. The biological system is then analyzed from a mechanical viewpoint by reducing it to its essential elements, using the laws of mechanics and then tying mechanical insights back to biological function. This integrated approach provides students with a deeper understanding of both the mechanics and the biology than from qualitative study alone. The text is supported by a wealth of illustrations, tables and examples, a large selection of suitable problems and hundreds of current references, making it an essential textbook for any biomechanics course.

Mechanics of Biomaterials
  • Fundamental Principles for Implant Design
  • Lisa A. Pruitt, Ayyana M. Chakravartula
  • Published online:
    05 June 2012
    Print publication:
    20 October 2011
  • Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry and soft tissue implants. Each chapter ends with a list of topical questions, making this an ideal course textbook for senior undergraduate and graduate students, and also a self-study tool for engineers, scientists and clinicians.

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