This paper identifies recurrent patterns in the political activity of American corporations that support trade. These firms have made public coalitions a central element of their pro-trade activities, and their collective efforts vastly outstrip those of trade's corporate opponents. This superiority in organization is paired with dramatically greater volumes of lobbying and campaign contributions. I explain these striking divergences by integrating collective action theory into a firm-centred model of trade politics: the heavy concentration of gains from trade among a small number of firms makes both individual and collective political action easier for pro-trade firms than for producers opposed to trade. This explanation is supported in panel analysis of firms’ participation in pro-trade coalitions, which shows that size, multinationality, and heterogeneity in global networks of production and sales drive participation in pro-trade groups. Globally engaged firms have supported trade by matching pro-trade preferences with highly organized political action.