There have been unsafe levels of unpaired fructose in the high fructose corn syrup (HFCS) in U.S. beverages, and research/case study evidence shows their intake is associated with greater asthma prevalence/risk/incidence, a debilitating disease, likely due to fructose-malabsorption, gut fructosylation, and gut dysbiosis mechanisms. The “unexplained” asthma epidemic has disproportionately affected children and Black individuals, groups with higher fructose-malabsorption prevalence than others, and research to assess disproportionately higher asthma risk/incidence among Black individuals in association with HFCS sweetened beverage intake is lacking.

Demographic, lifestyle, dietary data collected at enrollment/(1985-86), and incident asthma through exam 5/(1995-96), were used in Cox proportional hazards models to assess HFCS intake associations (hazard-ratios) with asthma risk/incidence.

CARDIA-Study participants from Birmingham, AL, Chicago, IL, Minneapolis, MN, and Oakland, CA.

1998 Black and 2104 White young adults.

HFCS sweetened beverage intake >once/wk was significantly associated with higher asthma risk relative to ≤ once/wk, (P-trend=0.04), among Black participants only; risk was 2.8 times higher among 2-4 times/wk consumers (HR=2.8, 95% CI 1.1-7.3, P=0.04), and 3.5 times higher when consumed multiple times/d, independent of sucrose intake/obesity/dietary quality/smoking/in-home smoke-exposure (HR=3.5, 95% CI 1.3-9.9, P=0.02). Intake of orange juice, with nominal unpaired fructose, was not associated with asthma in either group, nor was intake of sucrose, a disaccharide (paired) of fructose/glucose.

Ubiquitous HFCS in the U.S. food supply, with HFCS that contains high/unsafe unpaired fructose, a.k.a. excess-free-fructose, and the fructose/gut/lung/axis are overlooked risk factors in the “unexplained” U.S. asthma epidemic that disproportionately affects Black individuals.

To expand on prior literature by examining how various education parameters (performance-based reading literacy, years of education, and self-rated quality of education) relate to a cognitive screening measure's total and subscale scores of specific cognitive abilities.

Black adults (age range: 55–86) were administered self-rated items years of education and quality of education, and a measure of performance-based reading literacy. The Mini-Mental State Examination (MMSE) was used to screen for overall cognitive functioning as well as performance on specific cognitive abilities.

Sixty-nine percent of the sample had reading grade levels that were less than their reported years of education. Lower years of education and worse reading literacy are associated with poorer MMSE performance, particularly on the attention and calculation subscales.

Years of education, a commonly used measure for education, may not be reflective of Black adults’ educational experiences/qualities. Thus, it is important to account for the unique educational experiences of adults that could influence their MMSE performance. Incorporating quality and quantity of education will provide a more comprehensive understanding of the individual's performance on cognitive measures, specifically as it relates to sociocultural differences.