The paper uses unusually rich evidence from a manuscript life history written in 1901 from personal diaries to explore the changing relationship between home and workplace in Victorian London. The life history of Henry Jaques demonstrates the way in which decisions about employment and residence were related both to each other and to stages of the family life course. The uncertainty of work, lack of income to support a growing family, rising aspirations, the constant threat of illness, the ease of moving between rented property, close ties between home and workplace, the stresses produced by home working, and the attractions of suburbanization all interacted to shape the residential and employment history of Jaques and his family. The themes exemplified by this detailed life history were also relevant to many other people. Evidence collected from a large-scale project on lifetime residential histories is used to place the experiences of Henry Jaques in a broader context, and to show how they related to the changing social and economic structure of Victorian London.