Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-17T23:19:02.834Z Has data issue: false hasContentIssue false
  • English
  • Français

Reduction of coronary artery multi-slice computed tomographic radiation and maintained image interpretability by parameter optimization: the multicenter RAMBO study

Published online by Cambridge University Press:  15 November 2012

D. Pesenti rossi ,
G. Gibault-Genty ,
J.-L. Georges ,
R. Convers ,
N. Baron ,
S. Chayeb ,
L. Nay ,
G. Galuscan ,
C. Charbonnel  and
U. Balderacchi
...Show all authors
D. Pesenti rossi*
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
G. Gibault-Genty
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
J.-L. Georges
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
R. Convers
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
N. Baron
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
S. Chayeb
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
L. Nay
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
G. Galuscan
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
C. Charbonnel
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
U. Balderacchi
Affiliation:
Department of Radiology, Versailles Hospital, 177 rue de Versailles 78150 Le Chesnay France
CH. Hubert
Affiliation:
Department of Radiology, Versailles Hospital, 177 rue de Versailles 78150 Le Chesnay France
T. Fourme
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
B. Livarek
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
*
* e-mail: [email protected]
Get access

Abstract

Multi-slice computed tomography (MSCT) has proven inseveral studies to have a high diagnostic accuracy for the detectionor exclusion of coronary artery disease. A major concern with coronaryMSCT, however, is the associated radiation exposure of patients.Recent studies suggest that use of a 64-slice scanner is associatedwith a non-negligible lifetime attributable risk of cancer. Severalstrategies can be used to reduce patient exposure in coronary MSCT.The purpose of this multicenter study was to investigate the effectsof the adjustment of tube voltage and current on radiation doseand image interpretability. MSCT with retrospective ECG gating was performedin 315 patients. The dose-length product (DLP) in the patients enrolledwith the dose reduction protocol resulted in a 36% overall reductionin the mean radiation dose (911 ± 289 mGy.cm) compared with thestandard protocol (1427 ± 226 mGy.cm, p < 0.001).Nevertheless, image interpretability was maintained. This studyon coronary MSCT demonstrates that the radiation dose can be significantly reducedby parameter optimization, with maintained image interpretability.

Keywords

computed tomographyradiation dosecardiac imaging
Type
Research Article
Information
Radioprotection , Volume 48 , Issue 2 , April 2013 , pp. 181 - 189
Copyright
© EDP Sciences, 2013

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bongartz G., Golding S.J., Jurik A.G., et al. (2004) European Guidelines for Multislice Computed Tomography: Appendix C, Funded by the European Commission, March 2004.
Caussin, C. (2009) Positioning coronary multislice computed tomography as a pertinent tool for cardiac exploration, Arch. Cardiovasc. Dis. 102 (10), 673-675. Google ScholarPubMed
Caussin, C., Larchez, C., Ghostine, S., et al. (2006) Comparison of coronary minimal lumen area quantification by sixty-four-slice computed tomography versus intravascular ultrasound for intermediate stenosis, Am. J. Cardiol. 98, 871-876. Google Scholar
Einstein, A.J., Henzlova, M.J., Rajagopalan, S. (2007) Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography, JAMA 298 (3), 317-323. Google ScholarPubMed
Einstein, A.J., Elliston, C.D., Arai, A.E., et al. (2010) Radiation dose from single-heartbeat coronary CT angiography performed with a 320-detector row volume scanner, Radiology 254 (3), 698-706. Google ScholarPubMed
Georges, J.L., Pesenti-Rossi, D., Livarek, B. (2011) Controlling the radiation dose received by patients undergoing cardiac imaging, Future Cardiol. 7 (1), 1-5. Google ScholarPubMed
Hausleiter, J., Meyer, T., Hadamitzky, M., et al. (2006) Radiation dose estimates from cardiac multislice computed tomography in daily practice: impact of different scanning protocols on effective dose estimates, Circulation 113(10), 1305-1310. Google Scholar
Hausleiter, J., Martinoff, S., Hadamitzky, M., et al. (2010) Image quality and radiation exposure with a low tube voltage protocol for coronary CT angiography results of the PROTECTION II Trial, JACC Cardiovasc. Imag. 3 (11), 1113-1123. Google ScholarPubMed
ICRP publication 103 (2007) The 2007 Recommendations of the International Commission on Radiological Protection, Ann. ICRP 37 (2-4).
Leipsic, J., Labounty, T.M., Heilbron, B., et al. (2010) Adaptive statistical iterative reconstruction: assessment of image noise and image quality in coronary CT angiography, Am. J. Roentgenol. 195 (3), 649-654. Google Scholar
Leschka, S., Alkadhi, H., Plass, A., et al. (2005) Accuracy of MSCT coronary angiography with 64-slice technology: first experience, Eur. Heart J. 26, 1482-1487. Google ScholarPubMed
Mollet, N.R., Cademartiri, F., van Mieghem, C.A., et al. (2005) High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography, Circulation 112, 2318-2323. Google ScholarPubMed
Pernès, J.M., Sirol, M., Chabbert, V., et al. (2009) Current indications for cardiac CT, J. Radiol. 90 (9Pt2), 1123-1132. CrossRefGoogle ScholarPubMed
Pesenti-Rossi, D., Chouli, M., Gharbi, M., et al. (2011) Coronary aorto-ostial analysed by Multi-Slice Computed Tomography: A new tool for PCI?”, EuroIntervention 6 (6), 717-721. Google Scholar
Rehani, M.M. (2010) Radiation protection in newer imaging technologies, Radiat. Prot. Dosim. 139 (1-3), 357-362. Google ScholarPubMed
Schoenhagen, P. (2008) Back to the future: coronary CT angiography using prospective ECG triggering, Eur. Heart J. 29, 153-154. Google ScholarPubMed
Stolzmann, P., Leschka, S., Scheffel, H., et al. (2008) Dual-source CT in step-and-shoot mode: noninvasive coronary angiography with low radiation dose, Radiology 249 (1), 71-80. Google ScholarPubMed
Torres, F.S., Crean, A.M., Nguyen, E.T., et al. (2010) Strategies for radiation-dose reduction and image-quality optimization in multidetector computed tomographic coronary angiography, Can. Assoc. Radiol. J. 61 (5), 271-279. Google ScholarPubMed
Zanzonico, P., Rothenberg, L.N., Strauss, H.W. (2006) Radiation exposure of computed tomography and direct intracoronary angiography: risk has its reward, J. Am. Coll. Cardiol. 47 (9), 1846-1849. Google ScholarPubMed