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Reduction of coronary artery multi-slice computed tomographic radiation and maintained image interpretability by parameter optimization: the multicenter RAMBO study

Published online by Cambridge University Press:  15 November 2012

D. Pesenti rossi ,
G. Gibault-Genty ,
J.-L. Georges ,
R. Convers ,
N. Baron ,
S. Chayeb ,
L. Nay ,
G. Galuscan ,
C. Charbonnel  and
U. Balderacchi
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D. Pesenti rossi*
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
G. Gibault-Genty
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
J.-L. Georges
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
R. Convers
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
N. Baron
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
S. Chayeb
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
L. Nay
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
G. Galuscan
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
C. Charbonnel
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
U. Balderacchi
Affiliation:
Department of Radiology, Versailles Hospital, 177 rue de Versailles 78150 Le Chesnay France
CH. Hubert
Affiliation:
Department of Radiology, Versailles Hospital, 177 rue de Versailles 78150 Le Chesnay France
T. Fourme
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
B. Livarek
Affiliation:
Department of Cardiology, Versailles Hospital, 177 rue de Versailles, 78150 Le Chesnay, France
*
* e-mail: [email protected]
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Abstract

Multi-slice computed tomography (MSCT) has proven inseveral studies to have a high diagnostic accuracy for the detectionor exclusion of coronary artery disease. A major concern with coronaryMSCT, however, is the associated radiation exposure of patients.Recent studies suggest that use of a 64-slice scanner is associatedwith a non-negligible lifetime attributable risk of cancer. Severalstrategies can be used to reduce patient exposure in coronary MSCT.The purpose of this multicenter study was to investigate the effectsof the adjustment of tube voltage and current on radiation doseand image interpretability. MSCT with retrospective ECG gating was performedin 315 patients. The dose-length product (DLP) in the patients enrolledwith the dose reduction protocol resulted in a 36% overall reductionin the mean radiation dose (911 ± 289 mGy.cm) compared with thestandard protocol (1427 ± 226 mGy.cm, p < 0.001).Nevertheless, image interpretability was maintained. This studyon coronary MSCT demonstrates that the radiation dose can be significantly reducedby parameter optimization, with maintained image interpretability.

Keywords

computed tomographyradiation dosecardiac imaging
Type
Research Article
Information
Radioprotection , Volume 48 , Issue 2 , April 2013 , pp. 181 - 189
Copyright
© EDP Sciences, 2013

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