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Tea consumption and the reduced risk of colon cancer – results from a national prospective cohort study

Published online by Cambridge University Press:  02 January 2007

L Joseph Su  and
Lenore Arab
L Joseph Su*
Affiliation:
Stanley S Scott Cancer Center and Departments of Public Health and Preventive Medicine, Louisiana State University Health Sciences Center, 1600 Canal Street, Suite 800, New Orleans, LA 70112, USA
Lenore Arab
Affiliation:
Departments of Epidemiology and Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA
*
*Corresponding author: Email [email protected]
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Abstract

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Objective:

This study examines the relationship between tea consumption and colon cancer risk in the US population.

Design:

Data from the NHANES I Epidemiologic Follow-up study (NHEFS) were used to examine the hypothesis. Cox proportional hazard models were used to examine the hypothesis of a protective effect of frequent tea consumption on colon cancer occurrence.

Setting:

Due to differences in the precision of the exposure data, we analysed two cohort periods based on the NHEFS. Cohort I was based on the survey conducted at the NHEFS baseline and Cohort II began at the first follow-up.

Subjects:

After excluding non-incidence cases and cases lost to follow-ups, there were 2359 tea users and 6498 non-tea users at baseline and 7656 tea users and 4514 non-tea users at the first follow-up.

Results:

After adjusting for confounders, the relative risks of colon cancer are 0.57 (95% confidence interval (CI) 0.42, 0.78) and 0.59 (95% CI = 0.35, 1.00) for subjects who consumed ≤1.5 cups and ≥1.5 cups per day, respectively, compared with non-tea users in Cohort II. Although more women consumed tea and the mean intake was higher, the preventive effect of tea consumption on colon cancer was found predominantly in men. The relative risks of colon cancer are 0.41 (95% CI = 0.25, 0.66) for men who consumed ≤1.5 cups day-1 and 0.30 (95% CI = 0.09, 0.98) for >1.5 cups day-1 of tea consumption (P-value for trend <0.01). No significant results were found in Cohort I.

Conclusions:

This study suggests an inverse association between colon cancer risk and habitual tea consumption.

Keywords

TeaColon cancerNHEFS
Type
Research Article
Information
Public Health Nutrition , Volume 5 , Issue 3 , June 2002 , pp. 419 - 425
Copyright
Copyright © CABI Publishing 2002

References

1American Cancer Society. Cancer Facts and Figures: 1997. Atlanta, GA: American Cancer Society, Inc., 1997.Google Scholar
2Silverberg, E, Boring, C, Squires, T. Cancer statistics. CA: a Cancer Journal for Clinicians 1990; 40: 9–26.Google ScholarPubMed
3American Cancer Society. Estimated New Cancer Cases and Deaths by Sex for All Sites, United States, 2000. Atlanta, GA: American Cancer Society, Inc., 2000.Google Scholar
4Cassidy, A, Bingham, SA, Cummings, JH. Starch intake and colorectal cancer risk: an international comparison. Br. J. Cancer 1994; 69(5): 937–42.CrossRefGoogle ScholarPubMed
5Haenszel, W, Berg, JW, Segi, M, Kurihara, M, Locke, FB. Large-bowel cancer in Hawaiian Japanese. J. Natl. Cancer Inst. 1973; 51(6): 1765–79.CrossRefGoogle ScholarPubMed
6Whittemore, AS, Wu-Williams, AH, Lee, M, Zheng, S, Gallagher, RP, Jiao, DA, et al. Diet, physical activity, and colorectal cancer among Chinese in North America and China. J. Natl. Cancer Inst. 1990; 82(11): 915–26.CrossRefGoogle ScholarPubMed
7Adlercreutz, H, Gorbach, SL, Goldin, BR, Woods, MN, Dwyer, JT, Hamalainen, E. Estrogen metabolism and excretion in Oriental and Caucasian women. J. Natl. Cancer Inst. 1994; 86(14): 1076–82.CrossRefGoogle ScholarPubMed
8American Association for Cancer Research. Tea Affects the Formation of Heterocyclic Amines and Their Metabolism in Male and Female Rats. San Francisco, CA: American Association for Cancer Research, 2000.Google Scholar
9American Association for Cancer Research. Tea Polyphenols Inhibit Orthotopic Growth and Metastasis of Human Prostate Tumors in Mice. San Francisco, CA: American Association for Cancer Research, 2000.Google Scholar
10American Association for Cancer Research. Polyphenolic Extracts from Black Tea and Wine Protect Against Azoxymethane-induced Colon Carcinogenesis in Rats. San Francisco, CA: American Association for Cancer Research, 2000.Google Scholar
11American Association for Cancer Research. Effect of Tea and Tea Polyphenols on DNA Adduct Formation of Heterocyclic Amines (HCAS) in F344 Rats and CDF-1 Mice. San Francisco, CA: American Association for Cancer Research, 2000.Google Scholar
12National Center for Health Statistics (NCHS). National Center for Health Statistics: Plan and Operation of the Health and Nutrition Examination Survey, 1971–1973. Vital and Health Statistics. Rockville, MD: US Department of Health, Education, and Welfare, 1973.Google Scholar
13National Center for Health Statistics (NCHS). National Center for Health Statistics: Plan and Operation of the NHANES I Epidemiologic Follow-up Study, 1982–1984. Vital and Health Statistics. Rockville, MD: US Department of Health and Human Services, 1987.Google Scholar
14National Center for Health Statistics (NCHS). National Center for Health Statistics: Plan and Operation of the NHANES I Epidemiologic Follow-up Study, 1986. Vital and Health Statistics. Rockville, MD: US Department of Health and Human Services, 1990.Google Scholar
15National Center for Health Statistics (NCHS). National Center for Health Statistics: Plan and Operation of the NHANES I Augmentation Survey of Adults 25–74 years: United States, 1974–1975. Washington, DC: NCHS, 1978.Google Scholar
16Madans, JH, Cox, CS, Kleinman, JC, Makuc, D, Feldman, JJ, Finucane, FF, et al. 10 years after NHANES I: mortality experience at initial followup, 1982–84. Public Health Rep. 1986; 101(5): 474–81.Google ScholarPubMed
17Madans, JH, Kleinman, JC, Cox, CS, Barbano, HE, Feldman, JJ, Cohen, B. et al. 10 years after NHANES I: report of initial followup, 1982–84. Public Health Rep. 1986; 101(5): 465–73.Google ScholarPubMed
18Cornoni-Huntley, J, Barbano, HE, Brody, JA, Cohen, B, Feldman, JJ, Kleinman, JC, et al. National health and nutrition examination I – epidemiologic follow-up survey. Public Health Rep. 1983; 98(3): 245–51.Google ScholarPubMed
19Ji, B, Chow, W, Hsing, A, McLaughlin, J, Dai, Q, Gao, Y, et al. Green tea consumption and the risk of pancreatic and colorectal cancers. Int. J. Cancer 1997; 70(3): 255–8.3.0.CO;2-W>CrossRefGoogle ScholarPubMed
20Hartman, T, Tangrea, J, Pietinen, P, Malila, N, Virtanen, M, Taylor, P, et al. Tea and coffee consumption and risk of colon and rectal cancer in middle-aged Finnish men. Nutr. Cancer 1998; 31(1): 41–8.CrossRefGoogle ScholarPubMed
21Tavani, A, Pregnolato, A, La Vecchia, C, Negri, E, Talamini, R, Franceschi, S. Coffee and tea intake and risk of cancers of the colon and rectum: a study of 3,530 cases and 7,057 controls. Int. J. Cancer 1997; 73(2): 193–7.3.0.CO;2-R>CrossRefGoogle ScholarPubMed
22Persson, P, Carlsson, S, Grill, V, Hagman, U, Lundgren, A, Ostenson, C, et al. Food frequency questionnaire versus 7-day weighed dietary record information on dietary fibre and fat intake in middle-aged Swedish men. Scand. J. Social Med. 1998; 26(1): 75–80.CrossRefGoogle ScholarPubMed
23Brants, H, Lowik, M, Brussaard, J, Kistemaker, C, Van Erp-Baart, A. Food consumption methods. Development, reproducibility and validation of a food frequency questionnaire for vitamin B6. Eur. J. Clin. Nutr. 1997; 51(Suppl. 3): S12–8.Google ScholarPubMed
24Metcalf, P, Swinburn, B, Scragg, R, Dryson, E. Reproducibility and validity of a food frequency questionnaire in European and Polynesian New Zealanders. Ethnicity Health 1997; 2(4): 278–308.CrossRefGoogle ScholarPubMed
25Grootenhuis, P, Westenbrink, S, Sie, C, de Neeling, J, Kok, F, Bouter, L. A semiquantitative food frequency questionnaire for use in epidemiologic research among the elderly: validation by comparison with dietary history. J. Clin. Epidemiol. 1995; 48(7): 859–68.CrossRefGoogle ScholarPubMed
26Yang, C, Lee, M, Chen, L, Yang, G. Polyphenols as inhibitors of carcinogenesis. Environ. Health Perspect. 1997; 105(Suppl. 4): 971–6.Google ScholarPubMed
27Kohlmeier, L, Weterings, KG, Steck, S, Kok, FJ. Tea and cancer prevention: an evaluation of the epidemiologic literature. Nutr. Cancer 1997; 27(1): 1–13.CrossRefGoogle ScholarPubMed
28Ries, L, Kosary, C, Hankey, B, Miller, B, Clegg, L, Edwards, B. SEER Cancer Statistics Review, 1973–1976. Bethesda, MD: National Cancer Institute, 1999.Google Scholar
29Dawson, D, Archer, L. Gender differences in alcohol consumption: effects of measurement. Br. J. Addict. 1992; 87(1): 119–23.CrossRefGoogle ScholarPubMed
30Shillington, A, Clapp, J. Self-report stability of adolescent substance use: are there differences for gender, ethnicity and age? Drug Alcohol Depend. 2000; 60(1): 19–27.CrossRefGoogle ScholarPubMed
31Bujanda, L. The effects of alcohol consumption upon the gastrointestinal tract. Am. J. Gastroenterol. 2000; 95(12): 3374–82.CrossRefGoogle ScholarPubMed
32Hsing, A, McLaughlin, J, Chow, W, Schuman, L, Co Chien, H, Gridley, G. et al. Risk factors for colorectal cancer in a prospective study among US white men. Int. J. Cancer 1998; 77(4): 549–53.3.0.CO;2-1>CrossRefGoogle Scholar
33Tavani, A, Ferraroni, M, Mezzetti, M, Franceschi, S, Lo Re, A, La Vecchia, C. Alcohol intake and risk of cancers of the colon and rectum. Nutr. Cancer 1998; 30(3): 213–9.CrossRefGoogle ScholarPubMed
34Le Marchand, L, Wilkens, L, Kolonel, L, Hankin, J, Lyu, L. Associations of sedentary lifestyle, obesity, smoking, alcohol use, and diabetes with the risk of colorectal cancer. Cancer Res. 1997; 57(21): 4787–94.Google ScholarPubMed
35Giovannucci, E, Colditz, G, Stampfer, M, Hunter, D, Rosner, B, Willett, W, et al. A prospective study of cigarette smoking and risk of colorectal adenoma and colorectal cancer in US women. J. Natl. Cancer Inst. 1994; 86(3): 192–9.CrossRefGoogle Scholar