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Seasonal consumption of salad vegetables and fresh fruit in relation to the development of cardiovascular disease and cancer

Published online by Cambridge University Press:  02 January 2007

Brian D Cox ,
Margaret J Whichelow  and
A Toby Prevost
Brian D Cox*
Affiliation:
Health and Lifestyle Survey, Department of Community Medicine, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK.
Margaret J Whichelow
Affiliation:
Health and Lifestyle Survey, Department of Community Medicine, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK.
A Toby Prevost
Affiliation:
Centre for Applied Medical Statistics, Department of Community Medicine, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK.
*
*Corresponding author: Email [email protected]
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Abstract

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Objective

To investigate the protective association between seasonality of consumption of fresh fruit or salad vegetables and cancer and cardiovascular disease (CVD) development.

Design and setting

Face-to-face interviews, including a food frequency questionnaire, were conducted on 1489 men and 1900 women, aged 35–75 years, who were respondents in the British Health and Lifestyle Survey 1984/85 (HALS1). CVD and cancer morbidity and mortality were determined from the 1991/92 British Health and Lifestyle Survey (HALS2) and by NHS Register ‘flagging’.

Results

Risk was assessed by odds ratio (OR) for trend per frequency category. In men, frequent winter salad vegetable consumption was more closely protective than that in summer for cancer (winter OR = 0.79 [0.62–0.99], P = 0.045, summer OR = 0.83 [0.69–1.01], NS) and CVD (winter OR = 0.85 [0.72–1.00], P = 0.049, summer OR = 0.95 [0.82–1.10], NS). Fresh fruit consumption showed no significant protection. In women, frequent salad vegetable consumption at any season was significantly protective of CVD (winter OR = 0.76 [0.65–0.89], P < 0.001, summer OR = 0.76 [0.65–0.89], P < 0.001), although not of cancer. Frequent fresh fruit consumption in women was significantly protective of CVD (winter OR = 0.84 [0.74–0.94], P = 0.004, summer OR = 0.85 [0.74–0.97], P = 0.014) but not quite significant, and only in winter, for cancer (winter OR = 0.87 [0.76–1.00], P = 0.052, summer OR = 0.88 [0.75–1.02], P = 0.097). Maintenance of salad vegetable consumption from summer to winter, to within one frequency category, was associated with further protection for cancer in men (P = 0.050) and CVD in women (P = 0.024).

Conclusions

Diets high in fresh fruit and salad vegetables appear protective against cancer and CVD. It is important to take into account the seasonality of consumption in estimating and establishing significance of risk.

Keywords

Salad vegetablesFruitSeasonalityCardiovascular diseaseCancer
Type
Research Article
Information
Public Health Nutrition , Volume 3 , Issue 1 , March 2000 , pp. 19 - 29
Copyright
Copyright © CABI Publishing 2000

References

1Ness, A, Powles, JW. Fruit and vegetables, and cardiovascular disease: a review. Int. J. Epidemiol. 1996; 26: 1–13.CrossRefGoogle Scholar
2World Cancer Research Fund. Food Nutrition and the Prevention of Cancer: a Global Perspective. Washington: American Institute for Cancer Research, 1997; 442.Google Scholar
3National Food Survey Committee. Household Food Consumption and Expenditure: 1985. London: HMSO, 1987; 61–2.Google Scholar
4Cox, BD, Blaxter, M, Buckle, ALJ, et al. The Health and Lifestyle Survey. London: Health Promotion Research Trust, 1987.Google Scholar
5Cox, BD, Huppert, FA, Whichelow, MJ, et al. The Health and Lifestyle Survey: Seven Years On. Aldershot: Dartmouth Publishing Co Ltd, 1993.Google Scholar
6Powles, JW, Day, NE, Sanz, MA, Bingham, SA. Protective foods in winter and spring: a key to lower vascular mortality? Lancet 1996; 348: 898–9.CrossRefGoogle Scholar
7Strachan, DP, Cox, BD, Erzinclioglu, SW, Walters, DE, Whichelow, MJ. Ventilatory function and winter fresh fruit consumption in a random sample of British adults. Thorax 1991; 46: 624–9.CrossRefGoogle Scholar
8Whichelow, MJ, Treasure, FP. Diet and health in a random sample of British adults. Proc. Nutr. Soc. 1990; 49: 57A.Google Scholar
9Cox, BD, Whichelow, MJ. Seasonal fruit consumption in relation to the development of, or death from, cardiovascular disease. Proc. Nutr. Soc. 1998; 57: 61A.Google Scholar
10Cox, BD, Whichelow, MJ. Frequent consumption of red meat is not a risk factor for cancer. BMJ 1997; 315: 1018.CrossRefGoogle Scholar
11Blaxter, M. Sample and data collection. In: Cox, BD, Blaxter, M, Buckle, ALJ, et al. The Health and Lifestyle Survey. London: Health Promotion Research Trust, 1987; 1–3.Google Scholar
12Whichelow, MJ. Dietary habits. In: Cox, BD, Blaxter, M, Buckle, ALJ, et al. The Health and Lifestyle Survey. London: Health Promotion Research Trust, 1987; 67–84.Google Scholar
13Rogers, L, Sharp, I, National Heart Forum. Preventing Coronary Heart Disease: The Role of Antioxidants, Vegetables and Fruit. London: HMSO, 1997; 3.Google Scholar
14Department of Health. Nutritional Aspects of the Development of Cancer. Report on Health and Social Subjects No. 48. London: HMSO, 1998; 27.Google Scholar
15Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med. 1994; 330: 1029–35.CrossRefGoogle Scholar
16Hennekens, CH, Buring, JE, Manson, JE, et al. Lack of effect of long-term supplementation with beta-carotene on the incidence of malignant neoplasms and cardiovascular disease. N. Engl. J. Med. 1996; 334: 1145–9.CrossRefGoogle ScholarPubMed
17Omenn, GS, Goodman, GE, Thornquist, MD, et al. Effects of a combination of beta-carotene and vitamin A on lung cancer and cardiovascular disease. N. Engl. J. Med. 1996; 334: 1150–5.CrossRefGoogle ScholarPubMed
18Stephens, NG, Parsons, A, Schofield, PM, Kelly, F, Cheeseman, K, Mitchinson, MJ. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 1996; 347: 781–6.CrossRefGoogle ScholarPubMed
19Diplock, AT, Rogers, LA. Antioxidants and the development of coronary heart disease: the biological basis. In: Rogers, L, Sharp, I, eds. The National Heart Forum. Preventing Coronary Heart Disease: The Role of Antioxidants, Vegetables and Fruit. London: HMSO, 1997; 11–16.Google Scholar
20Knekt, P, Jarvinen, R, Reunanen, A, Maatela, J.Flavenoid intake and coronary mortality in Finland: a cohort study. BMJ 1996; 312: 478–81.CrossRefGoogle Scholar
21Giovannucci, E, Ascherio, A, Rimm, EB, Stampfer, MJ, Colditz, GA, Willett, WC. Intake of carotenoids and retinol in relation to risk of prostate cancer. J. Nat. Cancer Inst. 1995; 87: 1767–76.CrossRefGoogle ScholarPubMed
22Whichelow, MJ, Prevost, AT. Dietary patterns and their associations with demographic, lifestyle and health variables in a random sample of British adults. Br. J. Nutr. 1996; 76: 17–30.CrossRefGoogle Scholar
23Marmot, MG, Bosma, H, Hemingway, H, Brunner, E, Stansfield, S.Contribution of job control and other risk factors to social variations in coronary risk incidence. Lancet 1997; 350: 235–9.CrossRefGoogle Scholar
24Barker, DJP. The foetal origins of inequalities in health in Britain. J. Public Health Med. 1991; 13: 64–8.Google ScholarPubMed
25World Cancer Research Fund. Food Nutrition and the Prevention of Cancer: A Global Perspective. Washington: American Institute for Cancer Research, 1997; 37.Google Scholar
26Gaziano, JM, Manson, JE, Branch, LG, Colditz, GA, Willett, WC, Buring, JE. A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly. Ann. Epidemiol. 1995; 5: 255–60.CrossRefGoogle ScholarPubMed
27Gilman, MW, Cupples, LA, Gagnon, D, et al. Protective effect of fruits and vegetables on development of stroke in men. JAMA 1995; 273: 1113–17.CrossRefGoogle Scholar
28Whichelow, MJ, Erzinclioglu, SW, Cox, BD. A comparison of the diets of non-smokers and smokers. Br. J. Addict. 1991; 86: 71–81.CrossRefGoogle ScholarPubMed