Unhealthy diets are an important risk factor for the development of overweight, obesity and other nutrition-related non-communicable diseases and are therefore a global public health threat(Reference Lim, Vos and Flaxman1–Reference Amine, Baba and Belhadj3). A high intake of saturated fats, sugar and salt combined with a low intake of fish, fibre, vegetables and fruit characterises unhealthy dietary patterns, which are common in the Dutch population(Reference Bamia, Trichopoulos and Ferrari4,Reference de Vries, de Hoog and Stellinga5) . As a consequence, about half of the adult Dutch population is overweight and roughly 15 % has obesity(6). Despite continuous efforts to promote healthy diets, the consumption of energy-dense and nutrient-poor foods and drinks has increased in many high-income countries over the past decades, including the Netherlands(Reference Moubarac, Parra and Cannon7–Reference Imamura, Micha and Khatibzadeh9).
The retail food environment, which has been defined as the availability and accessibility of foods in people’s daily environment, has increasingly been recognised as a dominant determinant of food choice(Reference Albert, Amoroso and Garnett10–Reference Glanz, Sallis and Saelens13). Within this retail food environment, supermarkets have become a major source for individual and household food purchases(Reference Zorbas, Eyles and Orellana14–Reference Thompson, Cummins and Brown17). This is also the case in the Netherlands, where the majority of household food budget is spent in supermarkets(Reference de Vries, de Hoog and Stellinga5). Supermarkets use different marketing techniques to encourage food purchases(Reference Cameron, Sayers and Sacks18–Reference Charlton, Kähkönen and Sacks20). Among the main and most effective marketing techniques are the use of price promotions. Supermarket sales flyers are an important way of informing consumers about their assortment and discounts(Reference Glanz, Sallis and Saelens13,Reference Hawkes21,Reference Steenhuis, Waterlander and de Mul22) . In this way, such supermarket sales flyers can influence food purchasing decisions(Reference Geliebter, Ang and Bernales-Korins23), including product advertisement (no discount), temporary reduction in price (e.g. 10 % discount) or volume-based promotions (multi-buy), which are effective in increasing sales of the promoted products(Reference Ravensbergen, Waterlander and Kroeze24–Reference Familmaleki, Aghighi and Hamidi28).
Previous studies investigating the content of supermarket sales flyers found that most promoted products did not contribute to a healthy diet(Reference Martin-Biggers, Yorkin and Aljallad12,Reference Jahns, Scheett and Johnson15,Reference Cameron, Sayers and Sacks18–Reference Charlton, Kähkönen and Sacks20,Reference Ravensbergen, Waterlander and Kroeze24) . A recent study collected weekly online price data for 1 year from the largest Australian supermarket chain and found that price promotions were more prevalent and greater in magnitude for unhealthy foods than for healthy foods(Reference Riesenberg, Backholer and Zorbas29). Additionally, studies conducted in the UK found that customers that buy on promotions intend to buy greater amounts of less healthy products and less fruit and vegetables(30,Reference Coker, Rumgay and Whiteside31) . To our knowledge, literature on the promotions in supermarkets in the Netherlands is sparse. In a study from the Netherlands published in 2015, it was found that the majority of food promotions in supermarket sales flyers of four leading supermarket chains over an 8-week period were predominantly unhealthy (66·7 %)(Reference Ravensbergen, Waterlander and Kroeze24). They also reported significant differences in the number of healthy promotions (33·3 % v. 19·0 %) and the percentage discount of promoted products (28·0 % v. 21·0 %) between traditional and discount supermarkets. However, these findings represented supermarket sales flyers of 2012, and the retail food environment and the promotions of products are likely to have changed since then. For example, recent attention of policy-makers and the media to the importance of the retail food environment and the marketing of foods and drinks for public health has encouraged retailers to express their intentions to increase their efforts to support healthy food choices. As part of the Dutch National Prevention Agreement, supermarkets agreed to create a healthier food environment by promoting the purchase of foods and drinks that are compatible with the Dutch guidelines for a healthy diet(32). However, the implementation of these intentions is often vaguely described, and it is largely unclear which concrete actions are carried out to support a healthy diet. Besides, the degree of food processing of promoted products, which has become of interest due to a shift in food consumption from basic foods to (ultra-)processed foods in many countries, including the Netherlands(Reference Geurts, van Bakel and van Rossum8,Reference Monteiro, Moubarac and Cannon33) , has not been investigated for promotions in supermarket sales flyers. This is of interest because ultra-processed foods are often cheap, energy-dense and nutrient-poor(Reference Hawkes25) and have been associated with increased energetic intake and weight gain(Reference Hall, Ayuketah and Brychta26).
Therefore, the overall aim of this study was to investigate to what extent products promoted in Dutch supermarket sales flyers contribute to a healthy diet and whether there are differences between supermarket types. The results of this study may provide insights for the direction of policy and interventions to improve the healthiness of retail food environments, which in turn is likely to improve dietary behaviours.
Methods
Study design
A cross-sectional study was conducted, examining the products promoted via weekly online supermarket sales flyers of thirteen supermarket chains in the Netherlands, issued between February and April 2018.
Procedure and data collection
To extract the products promoted in supermarket sales flyers, we aimed to include most supermarket chains in the Netherlands based on degree of market share(34–36). In total, thirty-one unique supermarket chains were identified and characteristics were recorded (e.g. market share and type of supermarket). Only supermarket chains that distributed a weekly online sales flyer, which was identical in every region in the Netherlands, were included. Nine supermarket chains were excluded as a result of this criteria, leaving twenty-two supermarkets chains. Of these, a sample of ten traditional, two discount and one organic supermarket chains were selected, representing 95 % of national market share of all supermarket chains in 2018 in the Netherlands (Appendix 1). As our intention was to study the healthiness of food promotions in Dutch supermarket sales flyers, we avoid singling out particular supermarket chains and names are deliberately not declared.
All supermarket sales flyers (n 103) were sourced weekly online from the supermarket websites. To ensure reliability and accuracy, two researchers (AH and RJ) performed the data extraction of all supermarket sales flyers independently. Discrepancies were resolved and reviewed by the research team until unanimous agreement was achieved.
For the data extraction of the supermarket sales flyers, a pre-defined checklist was developed and used to collect the data. All products promoted in sales flyers were recorded and coded for supermarket name, type of supermarket chain (traditional, discount and organic) and were pooled over the 8-week period. If products from different product categories were promoted in one promotion (e.g. oranges (fruit) and yoghurt (milk and milk products), they were counted as two different product promotions. If similar products were promoted in one promotion (e.g. oranges and apples), they were calculated as one product promotion (fruit). Therefore, the number of promoted products included in the analyses exceeds the number of actual promotions that are analysed. Promoted non-food products were not recorded. Also, promotions including all products from a particular brand that represented a range of different food groups (e.g. Go-Tan sweet sauces and Go-Tan whole wheat noodles) were placed in a separate group ‘products not able to extract’ and excluded from data analysis (n 20 promotions).
Measures
Products promoted were first categorised per food group. Subsequently, products promoted were categorised with respect to their contribution to a healthy diet (yes/no), degree of processing, usual product price, promotional product price and type of promotion.
Food groups
All recorded products promoted via supermarket sales flyers were classified in food groups based on the description and categorisation of the Dutch Food Composition Database (also called the ‘NEVO table’)(37). The NEVO table contains data on the composition of foods and drinks consumed frequently by a large part of the Dutch population. For the purpose of this study, separate food groups were created for ‘Alcoholic drinks’ and ‘Non-alcoholic drinks’, since the NEVO table categorises both into the same food group. Additionally, unprepared tea and coffee in beans, powder, pad or cup form were placed in a separate food group, ‘Unprepared tea and coffee’, instead of the original NEVO food group ‘Alcoholic and non-alcoholic beverages’ as having incomparable nutritional values to liquid beverages. Lastly, olives were placed in the food group ‘Nuts, seeds and snacks’ instead of ‘Fruit’ (where olives were originally categorised according to the NEVO table), because olives are more typically consumed as a snack.
Some advertised products were not explicitly described in the NEVO table. These products were compared with similar products and placed in their most corresponding food group. For example, cheese straws of puff pastry were not included in the NEVO table and placed in the same food group as cheese rolls of puff pastry (‘Nuts, seeds and snacks’). Appendix 2 provides details about how the promoted products were classified over the twenty-five food groups.
Contribution to a healthy diet (‘healthiness’) of promoted products
To assess the contribution to a healthy diet (yes/no), all promoted products were assessed according to the Wheel of Five of the Netherlands Nutrition Centre that identifies all products that are included in the Dutch guidelines for a healthy diet(Reference Brink, Postma-Smeets and Stafleu38,Reference Brink, van Rossum and Postma-Smeets39) . For the purpose of this study, promoted products were categorised as ‘healthy’ or ‘less healthy’, using the ‘Do I choose healthy?’ app that integrates the criteria of the Wheel of Five. If a specific product was not available in the app, the nutrition facts label derived from the supermarket website was examined and manually classified by the researchers based on criteria of the Wheel of Five(Reference Brink, Postma-Smeets and Stafleu38,Reference Brink, van Rossum and Postma-Smeets39) . If the supermarket website did not provide the warranted product information to manually classify products, the nutrition facts label derived in the supermarket store was examined. In some cases, these products were not available in the supermarket and the nutrition facts label of a similar product offered by the same supermarket chain was used as reference instead (exact numbers were not recorded, we estimate that this was the case at less than ten products). If both healthy and less healthy foods and drinks were promoted together in one promotion, this promotion was classified in a separate category (‘varying healthiness’).
Degree of processing of products promoted
All products were categorised in either ‘Unprocessed/minimally processed foods’, ‘Processed culinary ingredients’, ‘Processed foods’ or ‘Ultra-processed food and drink products’, based on the NOVA food processing classification(Reference Monteiro, Cannon and Levy40). We were able to classify most products in their category based on the correspondence of the product’s nutrition facts label and the criteria of the NOVA food processing classification. In case the nutrition facts label was not available, the same procedure was followed as in the categorisation in Wheel of Five categories. If products of different food processing categories were promoted together in one promotion, this promotion was classified in a separate category (‘Varying in degree of food processing’). Appendix 3 shows the four NOVA food processing categories with explanation and examples of products per category.
Percentage discount on promoted products
Based on the usual product price and the promotional product price, percentage discount was calculated for every single promotion. If a promotion consisted of multiple products with varying prices, the average price across the price range, and subsequently the average percentage discount, was calculated.
Type of product promotions
For all products in supermarket sales flyers, the type of promotion was determined. In total thirty-six types of promotions were observed (outlined in Appendix 4), which were combined into three promotion groups: temporary reduction in price (e.g. 10 % discount), volume-based promotions (multi-buy discount) and advertised only (no discount).
Data analysis
In line with a similar Dutch study(Reference Ravensbergen, Waterlander and Kroeze24), all promoted products in a given week were pooled for the analyses. In total, there were promotions for 7825 products in the supermarket sales flyers over an 8-week period and these were the unit of analysis. Descriptive analyses were performed to gain insight into the healthiness of the promoted products, the distribution of the promoted products across the different food groups and the percentage discount of the price promotions per food group. Those healthy/less healthy products that were most often promoted and those products with the highest discount per food group and per supermarket type were examined.
Secondly, descriptive analyses and one-way ANOVA analyses were performed to study whether there were differences in percentage discount of the promoted products per healthiness category. ANOVA analyses were also performed to investigate differences between supermarket types in percentage discount of the promoted products per healthiness category and the degree of processing of the promoted products. In the statistical analyses, the products which were advertised only (no discount) were excluded when examining the percentage discount between promoted products per healthiness category or different types of supermarkets (n 1623 (20·7 %)).
Thirdly, to investigate whether there was a difference in types of promotions for the discounted food products per healthiness category, degree of processing and per supermarket type, chi-square analyses (Bonferroni adjusted) were performed. Furthermore, to investigate differences in the frequency of promoted products per healthiness category and degree of processing between supermarket types (traditional v. discount and traditional v. organic), chi-square analyses were performed. Two-sided P-values of <0·05 were considered statistically significant. All analyses were conducted using the IBM SPSS statistical software package, version 25.0.
Results
Table 1 provides an overview of the 7825 promoted products, specified by food group, and shows the healthiness, degree of processing, type of promotion and average discount per food group.
* Varying healthiness category (n 620 products) are not presented.
† ‘Processed Culinary Ingredients’ (n 41) and ‘Varying in degree of food processing’ (n 628) categories are not presented.
‡ Promoted products without discount (0 %) were excluded from data analysis (n 1623).
§ No SD because discount presented is for n 1.
Healthiness of promoted products (per food group and supermarket type)
In total, 21·3 % of all promoted products were healthy, whereas 70·7 % of the promoted products were less healthy. The top five most promoted products per food group were categorised as ‘Meat, meat products and poultry’ (12·9 %), followed by ‘Alcoholic beverages’ (11·1 %), ‘Pastry and biscuits’ (7·1 %), ‘Bread’ (6·9 %) and ‘Vegetables’ (6·5 %). In comparison with traditional supermarket chains, discount supermarket chains promoted a higher proportion of less healthy products (80·3 % v. 69·6 %, χ 2 = 53·40, P =< 0·001) and a lower proportion of healthy products (18·6 % v. 21·2 %, χ 2 = 3·99, P = 0·046). Organic supermarket chains promoted a lower proportion of less healthy products (56·2 % v. 69·6 %, χ 2 = 18·41, P =< 0·001) and a higher proportion of healthy products (37·6 % v. 21·2 %, χ 2 = 34·39, P =< 0·001), compared to traditional supermarket chains (Table 2).
Significant difference v. traditional supermarket: **P < 0·05, ***P < 0·01, ****P < 0·001.
* Varying healthiness category (n 620 products) are not presented.
† Data of ‘Processed Culinary Ingredients’ (n 41) and ‘Varying in degree of food processing’ (n 628) are not presented.
‡ Promoted products without discount (0 %) were excluded from data analysis (n 1623).
Degree of processing of the promoted products (per food group and supermarket type)
The majority of all promoted products were categorised as ‘Ultra-processed’ (56·6 %), followed by 20·4 % as ‘Unprocessed/minimally processed’, 14·5 % as ‘Processed’, 8·0 % as ‘Varying in degree of food processing’ and 0·5 % as ‘Processed culinary ingredients’. The top five of food groups with the highest proportion of promoted products that were categorised as ‘Unprocessed/minimally processed’ were the food groups ‘Eggs’ (100 %), ‘Fruit’ (91·6 %), ‘Vegetables’ (89·9 %), ‘Unprepared tea and coffee’ (89·2 %) and ‘Potatoes’ (51·8 %). The top five of food groups with the highest proportion of promoted products that were categorised as ‘Ultra-processed’ were the groups ‘Mixed dishes’ (97·8 %), ‘Pastry and biscuits’ (97·5 %), ‘Sugar, sweets and sweet sauces’ (95·3 %), ‘Soups’ (91·7 %) and ‘Bread’ (83·6 %), Table 1. Ultra-processed foods were significantly more often promoted by discount supermarket chains (65·1 %) compared to traditional supermarket chains (56·6 %) that in turn promoted more often ultra-processed foods than the organic supermarket chain (13·3 %, χ 2 = 340, P < 0·001) (Table 2).
Discount on promoted products (per food group, healthiness and degree of processing)
Irrespective of the frequency at which food groups were promoted, the top five products promoted with highest average discount were categorised as ‘Legumes’ (36·4 %), Soups (34·6 %), ‘Savoury bread spreads’ (32·6 %), Non-alcoholic beverages (31·5 %) and Potatoes (31·5 %) (Table 1). In total, the average percentage discount on less healthy products was similar to the average percentage discount on healthy products (28·7 % (sd 10·7) v. 28·9 % (sd 10·2), F = 0·20, P = 0·65). The average discount on unprocessed/minimally processed (29·4 %, sd = 10·6), processed (29·0 %, sd = 10·2) and ultra-processed foods (28·5 %, sd = 10·7) did not differ statistically.
Type of promotion per food group, healthiness and degree of processing
Top five products most frequently promoted products via temporary reduction in price per food group were ‘Alcoholic beverages’ (72·4 %), ‘Meat, meat products and poultry’ (61·2 %), ‘Cheese’ (59·9 %), ‘Fruit’ (60·0 %) and ‘Fish’ (56·5 %), Table 1. The food groups ‘Legumes’ (72·7 %), ‘Soups’ (59·4 %), ‘Herbs and spices’ (53·4 %), ‘Non-alcoholic beverages’ (48·6 %) and ‘Savoury bread spreads’ (48·3 %) were most often promoted via volume-based price promotions. Healthy promoted products were promoted more often by the use of a temporary reduction in price than less healthy products (74·6 % v. 62·4 %, χ 2 = 82·99, P < 0·001). Less healthy products were promoted more often via volume-based price promotions, compared to healthy products (37·6 % v. 25·4 %, χ 2 = 13·25, P < 0·001). Ultra-processed foods were also more often promoted via volume-based price promotions than unprocessed/minimally processed products (40·1 % v. 27·3 %, χ 2 = 171·63, P < 0·001).
Discussion
This study showed that the majority of the advertised and discounted products in Dutch supermarket sales flyers did not contribute to a healthy diet (70·7 %) and most were considered to be ultra-processed (56·6 %). Of all food groups, meat and meat products, alcoholic beverages, and pastry and biscuits were most frequently promoted. Moreover, less healthy and ultra-processed products were more frequently promoted through volume-based price promotions compared to healthy and unprocessed/minimally processed products, indicating that consumers who are looking for discounts are often tempted to buy larger quantities of less healthy and ultra-processed foods and drinks. Nevertheless, irrespective of the frequencies of the promoted products, the average magnitude of the discounts between healthy v. less healthy and unprocessed/minimally processed v. ultra-processed products promoted was not statistically different. We did observe differences between supermarket types. Discount supermarket chains promoted less healthy and ultra-processed products more frequently compared to traditional supermarket chains, while this was opposite for the organic supermarket chain. Traditional supermarket chains did, however, provide the highest average discount, followed by discount supermarkets and organic supermarket chain(s).
Based on our results, it can be concluded that the majority of Dutch supermarket chains do not promote the purchase of healthy products by means of promotions in their sales flyers. This is similar to the observations of Ravensbergen et al showing that 66·7 % of the supermarket circular promotions in 2012 were not in line with national dietary guidelines, despite the growing awareness on the importance of healthy retail environments in the past years(Reference Ravensbergen, Waterlander and Kroeze24). In 2018, supermarkets agreed to encourage healthier food choices as part of the National Prevention Agreement(32). Future studies should investigate if this can be achieved by self-regulation by supermarkets or needs to be enforced through government policies. Similar findings have been observed internationally, showing a high ratio of unhealthy-to-healthy products promoted in supermarket circulars in the USA, Australia, the UK, South Africa, Malaysia and Hong Kong(Reference Martin-Biggers, Yorkin and Aljallad12,Reference Jahns, Scheett and Johnson15,Reference Cameron, Sayers and Sacks18–Reference Charlton, Kähkönen and Sacks20,Reference Ethan, Samuel and Basch41,Reference Ethan, Basch and Rajan42) . Only supermarket sales flyers from particular supermarket chains in the Philippines, India, Sweden, Singapore and New Zealand seem to promote more healthy than unhealthy products, which was probably due to relatively high proportions of promotions for fruits and vegetables(Reference Charlton, Kähkönen and Sacks20). A possible explanation for the results of our study might be that it is more attractive for supermarkets to promote easy to store products with a longer shelf life, representing mainly less healthy and ultra-processed products, due to the fact that healthy fresh products are often difficult to stock and are less successful in boosting sales(Reference Monteiro, Cannon and Moubarac43).
An alarming finding of our study was that the frequency of promoted alcoholic drinks in our study has almost doubled compared to results of 2012 (11·1 % v. 6·3 %), although it should be considered that our study included a higher number of supermarket chains and therefore results are not fully comparable. In concordance with our results, studies from Australia, New Zealand and the UK showed a high percentage of alcoholic drinks (>12 %) in their circular promotions(Reference Charlton, Kähkönen and Sacks20).
Our results also support prior findings indicating that discount supermarket chains offer the least supportive environment for healthy food choices/purchases, compared to traditional and the organic supermarket chain(Reference Ravensbergen, Waterlander and Kroeze24,Reference Black, Ntani and Inskip44,Reference Camden, Levy and Bassil45) . Discount supermarket chains mainly attract consumers with a lower income, who have a higher sensitivity to lower prices compared to consumers with a higher socio-economic status(Reference Geurts, van Bakel and van Rossum8,Reference Zorbas, Eyles and Orellana14) and are also suffering more often from diet-related non-communicable diseases. On the contrary, the organic supermarket chain seem to offer the most supportive environment for healthy food purchases, promoting the highest proportion of healthy and unprocessed/minimally processed products compared to the other supermarket types (despite still half of the circular content of the organic supermarket chain included less healthy products). Average price discounts on products of the organic supermarket chain were lower than that of traditional supermarket chains. Notwithstanding the results that the organic supermarket had the healthiest flyers, it is well known that products sold are more expensive for consumers than discount and traditional supermarkets and thus less attractive for consumers with a low income.
This study has several strengths. First, data were collected for a variety of 13 supermarket chains, representing 95 % of total national market share and a broad range of consumer profiles and supermarket types. This increases the generalisability of the results, at least within the Netherlands. Second, promotions that represented two or more different food groups were recorded separately for each food group. Therefore, it was possible to limit the number of promoted products that could not be categorised and to assess supermarket sales flyers at the level of products per promoted food group. Third, this study is one of the first to explore the degree of food processing of promoted products in supermarket sales flyers. Ultra-processing of foods and drinks has become a more important determinant for the development of nutrition-related diseases and results of this study could be used for comparison with future international research(Reference Monteiro, Cannon and Moubarac43). Lastly, all types of promoted foods and drinks in all supermarket sales flyers were taken into account, which gives a complete overview of the range of products. Some studies only examined the first page of each circular, which could lead to an overestimation of food groups often advertised on the first page(Reference Martin-Biggers, Yorkin and Aljallad12,Reference Hawkes21,Reference Black, Ntani and Inskip44,Reference Camden, Levy and Bassil45) . However, limitations of this study must be noted as well. In accordance with other studies and to compare our results, this study was limited to an 8-week time frame for data collection and it is unclear how the results are generalisable across the year. We were also not able to test for seasonal variations in product promotions, and products may have been promoted more or less frequently due to seasonal dependency(Reference Riesenberg, Backholer and Zorbas29). In addition, the collection period included Valentine’s Day and Easter and, as a consequence, some particular products that are typically associated with festive occasions may have been promoted more frequently than usual (e.g. pastries and chocolates). However, a period of 8 weeks seems to be sufficient to reduce the effects of weekly variations in promoted products(Reference Charlton, Kähkönen and Sacks20). Furthermore, the current study focused on the content of supermarket sales flyers, even though other food environmental exposures in supermarkets, such as in-store location and discount information in other media, as well as less obvious marketing techniques, such as shape and size of portions and brand association, could also influence the purchase behaviour of consumers(Reference Brug16,Reference Thompson, Cummins and Brown17,Reference Chandon and Wansink46) . At last, this study included only two discount and one organic supermarket chain(s) compared to ten traditional supermarket chains. Therefore, findings between supermarket types may have been influenced as a result of the large variation in sample sizes. Especially results concerning the differences between the organic supermarket chains and traditional supermarket chains should be interpreted with caution, due to the small number of promoted products for the organic supermarket chain.
Since supermarkets have a major and increasing influence on food purchases, it would be promising if further research investigates the effects of a healthier content of supermarket sales flyers on the actual purchasing and consumption behaviours. It is not only important for supermarkets to discount healthier foods more often, it is also of is also particular importantance that unhealthy foods are less frequently promoted. The relations between food pricing and purchases, particularly in low-income households, are complex(Reference Bennett, Zorbas and Huse47). Future research should focus on the broader food system and investigate leverage points within the food system that can influence product and price promotions. Moreover, policy-makers can contribute to the creation of a healthier (retail) food environment by implementing policies with regard to the regulation of price promotions on healthy and unhealthy foods in supermarket sales flyers.
Conclusion
This study demonstrated that Dutch supermarket chains predominantly implement promotions to products that are not recommended in the national dietary guidelines. This may contribute to purchases and consumption of unhealthy products which, in turn, may contribute to the development of nutrition-related chronic diseases. Since Dutch supermarkets have committed themselves to encourage consumers to eat a healthy diet, a suitable way would be to increase the ratio of healthy-to-unhealthy promoted products in order to facilitate purchases of healthier products. More research is needed to determine whether these changes will contribute to healthier food purchases and diets.
Acknowledgements
Acknowledgements: N/A. Financial support: The contribution of the final author (MPP) was funded by the Innovational Research Incentives Scheme Veni (grant number 451-16-029), financed by the Netherlands Organisation for Scientific Research (NWO). Conflict of interest: None. Authorship: AH and RJ formulated the research questions and collected the data, analysed the data, drafted a first version of the manuscript. MPP and CD designed the study, contributed to the formulation of the research question and analysing the data, and critically reviewed and revised the final version of the manuscript. MH and JS critically reviewed the manuscript. All authors approved the final version of the manuscript for submission. Ethics of human subject participation: Approval of the study by the Medical Ethics Committee was not required.
Supplementary material
For supplementary material accompanying this paper, visit https://doi.org/10.1017/S1368980021001233