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The association of diet and other lifestyle factors with the onset of overactive bladder: a longitudinal study in men

Published online by Cambridge University Press:  02 January 2007

Helen M Dallosso ,
Ruth J Matthews ,
Catherine W McGrother ,
Madeleine MK Donaldson  and
Chris Shaw
Helen M Dallosso*
Affiliation:
Department of Health Sciences, University of Leicester, 22–28 Princess Road West, Leicester, LE1 6TP, UK
Ruth J Matthews
Affiliation:
Department of Health Sciences, University of Leicester, 22–28 Princess Road West, Leicester, LE1 6TP, UK
Catherine W McGrother
Affiliation:
Department of Health Sciences, University of Leicester, 22–28 Princess Road West, Leicester, LE1 6TP, UK
Madeleine MK Donaldson
Affiliation:
Department of Health Sciences, University of Leicester, 22–28 Princess Road West, Leicester, LE1 6TP, UK
Chris Shaw
Affiliation:
Department of Health Sciences, University of Leicester, 22–28 Princess Road West, Leicester, LE1 6TP, UK
*
*Corresponding author: Email [email protected]
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Abstract

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Objective:

To investigate associations between diet and non-dietary lifestyle factors and the onset of overactive bladder (OAB) in men.

Subjects:

Random sample of community-dwelling men aged 40 years plus.

Design and methods: Baseline data on urinary symptoms and diet were collected from 5454 men using a postal questionnaire and a food-frequency questionnaire. Follow-up data on urinary symptoms were collected from 4887 men in a postal survey one year later. Logistic regression analysis was used to investigate diet and lifestyle factors associated with onset of OAB in the men without OAB at baseline.

Results:

There was a highly significant negative association between beer intake at baseline and subsequent OAB onset (P = 0.001), with reduced risk at all levels of intake compared with those who seldom/never drank beer. Adjustment for total alcohol intake (g ethanol day−1) reduced the significance of the association (P = 0.02). None of the food groups studied was associated with OAB onset, with the possible exception of potatoes (P = 0.05), which showed an increased risk of onset at the highest level of consumption. Physical activity, smoking and obesity were not significantly associated.

Conclusions:

While most diet and lifestyle factors were not associated with OAB onset, the evidence from this prospective longitudinal study suggests that beer may have a protective role in the development of OAB. This could be due to a non-alcoholic ingredient as well as the alcohol content.

Keywords

Overactive bladderFood-frequency questionnaireLifestyleMenLongitudinal studyDietary intake
Type
Research Article
Information
Public Health Nutrition , Volume 7 , Issue 7 , October 2004 , pp. 885 - 891
Copyright
Copyright © The Authors 2004

References

1Abrams, P, Cardozo, L, Fall, M, Griffiths, D, Rosier, P, Ulmsten, U, et al. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Neurourology and Urodynamics 2002; 21: 167–78.CrossRefGoogle ScholarPubMed
2Abdel-Aziz, KF, Lemack, G. Overactive bladder in the male patient: bladder, outlet, or both? Current Urology Reports 2002; 3: 445–51.Google Scholar
3De Groat, WC. A neurologic basis for the overactive bladder. Urology 1997; 50: 36–52.CrossRefGoogle ScholarPubMed
4Rana, S, D'Amico, F, Merenstein, JH. Relationship of vitamin B-12 deficiency with incontinence in older people. Journal of the American Geriatric Society 1998; 46: 931–2.CrossRefGoogle ScholarPubMed
5Brading, AF. A myogenic basis for the overactive bladder. Urology 1997; 50: 57–67.CrossRefGoogle ScholarPubMed
6Brown, JS, Grady, D, Ouslander, JG, Herzog, AR, Varner, E, Posner, SF. Prevalence of urinary incontinence and associated risk factors in post-menopausal women. Obstetrics and Gynecology 1999; 94: 66–70.Google Scholar
7Moller, LA, Lose, G, Jorgensen, T. Risk factors for lower urinary tract symptoms in women 40 to 60 years of age. Obstetrics and Gynecology 2000; 96: 446–51.CrossRefGoogle Scholar
8Muscatello, DJ, Rissel, C, Szonyi, G. Urinary symptoms and incontinence in an urban community: prevalence and associated factors in older men and women. Internal Medicine Journal 2001; 31: 151–60.CrossRefGoogle Scholar
9Bortolotti, A, Bernardini, B, Colli, E, Di Benedetto, P, Nacci, GG, Landoni, M, et al. Prevalence and risk factors for urinary incontinence in Italy. European Urology 2000; 37: 30–5.CrossRefGoogle ScholarPubMed
10Dallosso, HM, McGrother, CW, Matthews, RJ, Donaldson, MMK. The association of diet and other lifestyle factors with overactive bladder and stress incontinence: a longitudinal study in women. BJU International 2003; 92: 69–77.CrossRefGoogle ScholarPubMed
11Dallosso, HM, Matthews, RJ, McGrother, C, Clarke, M, Perry, S, Shaw, C, et al. An investigation into non-response bias in a postal survey on urinary symptoms. BJU International 2003; 91: 631–6.CrossRefGoogle Scholar
12Perry, S, Shaw, C, Assassa, P, Dallosso, HM, Williams, K, Brittain, KR, et al. An epidemiological study to establish the prevalence of urinary symptoms and felt need in the community: the Leicestershire MRC Incontinence Study. Journal of Public Health Medicine 2000; 22: 427–34.CrossRefGoogle ScholarPubMed
13Bingham, SA, Welch, A, McTaggart, A, Mulligan, A, Runswick, S, Luben, R, et al. Nutritional methods in the European Prospective Investigation of Cancer in Norfolk. Public Health Nutrition 2001; 4: 847–58.CrossRefGoogle ScholarPubMed
14Ware, JE, Snow, KK, Kosinski, M, Gandek, B. SF-36 Health Survey Manual and Interpretation Guide. Boston, MA: The Health Institute, 1993.Google Scholar
15Prezioso, D, Catuogno, C, Galassi, P, D'Andrea, G, Castello, G, Pirritano, D. Lifestyle in patients with LUTS suggestive of BPH. European Urology 2001; 40: 9–12.Google Scholar
16Koskimaki, J, Hakama, M, Huhtala, H, Tammela, TL. Association of dietary elements and lower urinary tract symptoms. Scandinavian Journal of Urology and Nephrology 2000; 34: 46–50.CrossRefGoogle ScholarPubMed
17Platz, EA, Kawachi, I, Rimm, EB, Colditz, GA, Stampfer, MJ, Willett, WC, et al. Physical activity and benign prostatic hyperplasia. Archives of Internal Medicine 1998; 158: 2349–56.Google Scholar
18Schmidbauer, J, Temml, C, Schatzl, G, Haidinger, G, Madersbacher, S. Risk factors for urinary incontinence in both sexes – analysis of a health screening project. European Urology 2001; 39: 565–70.CrossRefGoogle ScholarPubMed
19Brown, JS, Seeley, DG, Fong, J, Black, DM, Ensrud, KE, Grady, D. Urinary incontinence in older women: who is at risk? Obstetrics and Gynecology 1996; 87: 715–21.Google Scholar
20Ohmura, M, Kondo, A, Saito, M. Effects of ethanol on responses of isolated rabbit urinary bladder and urethra. International Journal of Urology 1997; 4: 295–9.Google Scholar
21Yokoi, K, Ohmura, M, Kondo, A, Miyake, K, Saito, M. Effects of ethanol on in vivo cystometry and in vitro whole bladder contractility in the rat. Journal of Urology 1996; 156: 1489–91.CrossRefGoogle ScholarPubMed
22Knight, GE, Brizzolara, AL, Soediono, PO, Karoon, P, Burnstock, G. Chronic ethanol-consumption affects cholinoceptor-mediated and purinoceptor-mediated contractions of the isolated rat bladder. Alcohol 1995; 12: 183–8.CrossRefGoogle Scholar
23Kim, HJ, Moon, H, Sohng, I, Lee, HW, Lee, G, Lee, JG. Effects of ethanol and its metabolite acetaldehyde on responses of the rat bladder. BJU International 1999; 83: 686–92.CrossRefGoogle ScholarPubMed
24Ida, Y, Tsujimaru, S, Nakamaura, K, Shirao, I, Mukasa, H, Egami, H, et al. Effects of acute and repeated alcohol ingestion on hypothalamic–pituitary–gonadal and hypothalamic–pituitary–adrenal functioning in normal males. Drug and Alcohol Dependence 1992; 31: 57–64.CrossRefGoogle ScholarPubMed
25Couwenbergs, CJ. Acute effects of drinking beer or wine on the steroid hormones of healthy men. Journal of Steroid Biochemistry 1988; 31: 467–73.Google Scholar
26Ratz, PH, McCammon, KA, Altstatt, D, Blackmore, PF, Shenfeld, OZ, Schlossberg, SM. Differential effects of sex hormones and phytoestrogens on peak and steady state contractions in isolated rabbit detrusor. Journal of Urology 1999; 162: 1821–8.Google Scholar
27Allen, NE, Key, TJ. Sex hormones and diet in men. Nutrition Research Reviews 2000; 13: 159–84.CrossRefGoogle Scholar
28Selhub, J, Jacques, PF, Wilson, P, Rush, D, Rosenberg, IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. Journal of the American Medical Association 1993; 270: 2693–8.CrossRefGoogle Scholar
29Eikelboom, JW, Lonn, E, Genest, J, Hankey, G, Yusuf, S. Homocysteine and cardiovascular disease: a critical review of the epidemiologic evidence. Annals of Internal Medicine 1999; 131: 363–75.Google Scholar
30Diaz-Arrastia, R. Homocysteine and neurologic disease. Archives of Neurology 2000; 57: 1422–7.Google Scholar
31De Bree, A, Verschuren, WM, Blom, HJ, Kromhout, D. Association between B vitamin intake and plasma homocysteine concentration in the general Dutch population aged 20–65y. American Journal of Clinical Nutrition 2001; 73: 1027–33.CrossRefGoogle Scholar
32Lapcik, O, Hill, M, Hampl, R, Wahala, K, Adlercreutz, H. Identification of isoflavonoids in beer. Steroids 1998; 63: 14–20.Google Scholar
33Slanina, P. Solanine (glycoalkaloids) in potatoes – toxicological evaluation. Food Chemistry and Toxicology 1990; 28: 759–61.CrossRefGoogle ScholarPubMed
34Mommsen, S, Foldspang, A. Body mass index and adult female urinary incontinence. World Journal of Urology 1994; 12: 319–22.Google Scholar
35Baron, JA. Smoking and estrogen-related disease. American Journal of Epidemiology 1984; 119: 9–22.CrossRefGoogle ScholarPubMed
36Platz, EA, Rimm, EB, Kawachi, I, Colditz, GA, Stampfer, MJ, Willett, WC, et al. Alcohol consumption, cigarette smoking, and risk of benign prostatic hyperplasia. American Journal of Epidemiology 1999; 149: 106–15.Google Scholar
37Ellgring, H, Seiler, S, Perleth, B, Frings, W, Gasser, T, Oertal, W. Psychosocial aspects of Parkinson's disease Neurology 1993; 43: S41–4.Google ScholarPubMed
38Morrison, AS. Risk factors for surgery for prostatic hypertrophy. American Journal of Epidemiology 1992; 135: 974–80.Google Scholar
39Chyou, P, Nomura, A. A prospective study of alcohol, diet, and other lifestyle factors in relation to obstructive uropathy. Prostate 1993; 22: 253–64.Google Scholar
40Amanatidis, S, Mackerras, D, Simpson, JM. Comparison of two frequency questionnaires for quantifying fruit and vegetable intake. Public Health Nutrition 2001; 4: 233–9.CrossRefGoogle ScholarPubMed
41Willett, WC. Nutritional Epidemiology. New York: Oxford University Press, 1998.Google Scholar