Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-22T15:40:21.013Z Has data issue: false hasContentIssue false
  • English
  • Français

Peptide utilization by tissues: current status and applications of stable isotope procedures

Published online by Cambridge University Press:  28 February 2007

F. R. Colette Backwell
F. R. Colette Backwell
Affiliation:
Rowett Research Institute, Bucksburn, Aberdeen AB2 9SB
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
E & PMG Workshop
Information
Proceedings of the Nutrition Society , Volume 53 , Issue 3 , November 1994 , pp. 457 - 464
Copyright
Copyright © The Nutrition Society 1994

References

Adibi, S. A. (1971). Intestinal transport of dipeptides in man: Relative importance of hydrolysis and intact absorption. Journal of Clinical Investigation 50, 2266–2275.CrossRefGoogle ScholarPubMed
Adibi, S. A. (1987). Experimental basis for use of peptides as substrates for parenteral nutrition: a review. Metabolism 36, 1001–1011.CrossRefGoogle ScholarPubMed
Adibi, S. A., Krzysik, B. A. & Drash, A. L. (1977). Metabolism of intravenously administered dipeptides in rats: effects on amino acid pools, glucose concentration and insulin and glucagon secretion. Clinical Science and Molecular Medicine 52, 193–204.Google ScholarPubMed
Backwell, F. R. C., Bequette, B. J., Metcalf, J. A., Wray-Cahen, D., France, J., Crompton, L., Beever, D. E., Lobley, G. E. & MacRae, J. C. (1994 a). Peptide utilisation by the mammary gland of lactating dairy goats. Animal Production (In the Press).Google Scholar
Backwell, F. R. C., Bequette, B. J., Wilson, D., Calder, A. G., Wray-Cahen, D., Metcalf, J. A., MacRae, J. C., Beever, D. E. & Lobley, G. E. (1994 b). The utilisation of dipeptides by the caprine mammary gland for milk protein synthesis. American Journal of Physiology (In the Press).Google ScholarPubMed
Baird, G. D., Lomax, M. A., Symonds, H. W. & Shaw, S. R. (1980). Net hepatic and splanchnic metabolism of lactate, pyruvate and propionate in dairy cows in vivo in relation to lactation and nutrient supply. Biochemical Journal 186, 47–57.CrossRefGoogle ScholarPubMed
Bequette, B. J., Backwell, F. R. C., Wilson, D., Walker, A., Calder, A. G., Wray-Cahen, D., Metcalf, J. A., Lobley, G. E. & MacRae, J. C. (1994). Kinetics of milk casein labelling in dairy goats at different stages of lactation. British Journal of Nutrition 72, 211–220.CrossRefGoogle Scholar
Bickerstaffe, R., Annison, E. F. & Linzell, J. F. (1974). The metabolism of glucose, acetate, lipids and amino acids in lactating cows. Journal of Agricultural Science 82, 71–85.CrossRefGoogle Scholar
Druml, W., Roth, E., Lenz, K., Lochs, H. & Kopoa, H. (1989). Phenylalanine and tyrosine metabolism in renal failure: dipeptides as tyrosine source. Kidney International 36, Suppl. 27, S-282–S-286.Google Scholar
Elwyn, D. H. (1970). The role of the liver in regulation of amino acid and protein metabolism. In Mammalian Protein Metabolism, pp. 523–557 [Munro, H. N., editor]. New York: Academic Press.CrossRefGoogle Scholar
Elwyn, D. H., Parikh, H. C. & Shoemaker, W. C. (1968). Amino acid movements between gut, liver and periphery in unanaesthetized dogs. American Journal of Physiology 215, 1260–1275.CrossRefGoogle Scholar
Furst, P. (1985). Peptides in parenteral nutrition. Clinical Nutrition 4, 105–115.CrossRefGoogle Scholar
Furst, P., Albers, S. & Stehle, P. (1990). Dipeptides in clinical nutrition. Proceedings of the Nutrition Society 49, 343–359.CrossRefGoogle ScholarPubMed
Gallibois, I., Pitre, F., Parent, G. & Savoie, L. (1991). Analysis of bound amino acids in the plasma of fed rats: a new preparation procedure. Journal of Nutritional Biochemistry 2, 25–30.CrossRefGoogle Scholar
Ganapathy, V. & Leibach, F. H. (1983). Role of pH gradient and membrane potential in dipeptide transport in intestinal and renal brush-border membrane vesicles from the rabbit. Journal of Biological Chemistry 258, 14189–14192.CrossRefGoogle ScholarPubMed
Ganapathy, V., Miyamoto, Y. & Leibach, F. H. (1987). Driving force for peptide transport in mammalian intestine and kidney. Contributions to Infusion Therapy and Clinical Nutrition, vol. 17, pp. 54–68 [Adibi, S. A. Fekl, W. E. Furst, P. and Oehmke, M., editors]. Basel: Karger.Google Scholar
Gardner, M. L., Illingworth, K. M., Kelleher, J. & Wood, D. (1991). Intestinal absorption of the intact peptide carnosine in man and comparison with intestinal permeability to lactulose. Journal of Physiology 439, 411–422.CrossRefGoogle ScholarPubMed
Gardner, M. L. G., Lindblad, B. S., Burston, D. & Matthews, D. M. (1983). Transmucosal passage of intact peptides in the guinea-pig small intestine in vivo: a reappraisal. Clinical Science 64, 433–439.CrossRefGoogle ScholarPubMed
Grimble, G. K. (1994). The significance of peptides in clinical nutrition. Annual Review of Nutrition 14, 419–447.CrossRefGoogle ScholarPubMed
Grimble, G. K. & Silk, D. B. A. (1989). Peptides in human nutrition. Nutrition Research Reviews 2, 87–108.CrossRefGoogle ScholarPubMed
Hubl, W., Druml, W., Langer, K. & Lochs, H. (1989). Influence of molecular structure and plasma hydrolysis on the metabolism of glutamine-containing dipeptides in humans. Metabolism 38, Suppl. 1, 59–62.CrossRefGoogle Scholar
Koeln, L. L., Schlagheck, T. G. & Webb, K. E. (1993). Amino acid flux across the gastrointestinal tract and liver of calves. Journal of Dairy Science 76, 2275–2285.CrossRefGoogle ScholarPubMed
Lochs, H., Morse, E. & Adibi, S. A. (1986). Mechanism of hepatic assimilation of peptides. Journal of Biological Chemistry 261, 14976–14981.CrossRefGoogle Scholar
Lochs, H., Williams, P. E., Morse, E. L., Abumrad, N. N. & Adibi, S. A. (1988). Metabolism of dipeptides and their constituent amino acids by liver, gut, kidney and muscle. American Journal of Physiology 254, E588–E594.Google ScholarPubMed
McCormick, M. E. & Webb, K. E. (1982). Plasma free, erythrocyte free and plasma peptide amino acid exchange of calves in steady state and fasting metabolism. Journal of Nutrition 112, 276–282.CrossRefGoogle ScholarPubMed
McCormick, M. E. & Webb, K. E. (1987). Serum proteins as carriers of amino acids to and from the hindlimbs of fed and fasted calves. Journal of Animal Science 64, 586–593.CrossRefGoogle ScholarPubMed
MacRae, J. C., Lobley, G. E., Bruce, L. A., Luo, Q., Calder, A. G. & Farningham, D. A. H. (1993). Leucine kinetics across the portal drained viscera of sheep. Journal of Animal Science 71, Suppl. 1, 755 Abstr.Google Scholar
Matthews, D. M. (1975). Intestinal absorption of peptides. Physiological Reviews 55, 537–608.CrossRefGoogle ScholarPubMed
Metcalf, J. A., Beever, D. E., Sutton, J. D., Wray-Cahen, D., Evans, R. T., Humphries, D. J., Backwell, F. R. C., Bequette, B. J. & MacRae, J. C. (1994). The effect of supplementary protein on in vivo metabolism of the mammary gland in lactating dairy cows. Journal of Dairy Science (In the Press).CrossRefGoogle ScholarPubMed
Pocius, P. A., Clark, J. H. & Baumrucker, C. R. (1981). Glutathione in bovine blood: possible source of amino acids for milk protein synthesis. Journal of Dairy Science 64, 1551–1554.CrossRefGoogle ScholarPubMed
Rérat, A., Simoes-Nuñes, C., Mendy, F., Vaissade, P. & Vaugelade, P. (1992). Splanchnic fluxes of amino acids after duodenal infusion of carbohydrate solutions containing free amino acids or oligopeptides in the non-anaesthetized pig. British Journal of Nutrition 68, 111–138.CrossRefGoogle ScholarPubMed
Roth, E., Kerner, J., Ollenschlager, G., Karner, J., Simmel, A., Furst, P. & Funovics, J. (1988). Alanylglutamine reduces muscle loss of alanine and glutamine in post-operative anaesthetised dogs. Clinical Science 75, 641–648.CrossRefGoogle Scholar
Seal, C. J. & Parker, D. S. (1991). Isolation and characterisation of circulating low molecular weight peptides in steer, sheep and rat portal and peripheral blood. Comparative Biochemistry and Physiology 99B, 679–685.Google Scholar
Steinhardt, H. J., Paleos, G. A., Brandl, M., Fekl, W. E. & Adibi, S. A. (1984). Efficacy of a synthetic dipeptide mixture as a source of amino acids for total parenteral nutrition in a subhuman primate (baboon). Gastroenterology 86, 1562–1569.CrossRefGoogle Scholar
Steininger, R., Karner, J., Roth, E. & Langer, K. (1989). Infusion of dipeptides as nutritional substrates for glutamine, tyrosine and branched-chain amino acids in patients with acute pancreatitis. Metabolism 38, Suppl. 1, 78–81.CrossRefGoogle ScholarPubMed
Tagari, H. & Bergman, E. N. (1977). Intestinal disappearance and portal blood appearance of amino acids in sheep. Journal of Nutrition 108, 790–803.CrossRefGoogle Scholar
Webb, K. E., Matthews, J. C. & DiRienzo, D. B. (1992). Peptide absorption: a review of current concepts and future perspectives. Journal of Animal Science 70, 3248–3257.CrossRefGoogle ScholarPubMed
Wolff, J. E., Bergman, E. N. & Williams, H. H. (1972). Net metabolism of plasma amino acids by liver and portal-drained viscera of fed sheep. American Journal of Physiology 223, 438–446.CrossRefGoogle ScholarPubMed