Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-22T15:15:49.282Z Has data issue: false hasContentIssue false
  • English
  • Français

Assessment of Zinc Status

Published online by Cambridge University Press:  28 February 2007

R. P. H. Thompson
R. P. H. Thompson
Affiliation:
St Thomas' Hospital, LondonSE1 7EH
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Workshop on ‘Assessment of zinc status’
Information
Proceedings of the Nutrition Society , Volume 50 , Issue 1 , March 1991 , pp. 19 - 28
Copyright
Copyright © The Nutrition Society 1991

References

Aamodt, R. L., Rumble, W. F., Babcock, A. K., Foster, D. M. & Henkin, R. I. (1982). Effects of oral zinc loading on zinc metabolism in humans. I. Experimental studies. Metabolism 31, 326–334.Google Scholar
Ainley, C. C., Cason, J., Carlsson, L. K., Slavin, B. M. & Thompson, R. P. H. (1988). Zinc status in inflammatory bowel disease. Clinical Science 75, 277–283.Google Scholar
Anon (1985). Copper deficiency induced by megadoses of zinc. Nutrition Reviews 43, 148–149.Google Scholar
Apgar, J. & Fitzgerald, J. A. (1987). Measure of zinc status in ewes given a low zinc diet throughout pregnancy. Nutrition Research 7, 1281–1290.Google Scholar
Baer, M. T. & King, J. C. (1984). Tissue zinc levels and zinc excretion during experimental zinc depletion in young men. American Journal of Clinical Nutrition 39, 556–570.Google Scholar
Blendis, L. M., Wesson, D., Doody, M., Allen, L. C., Dietrich, L. & Goldberg, E. M. (1978). Zinc deficiency in cirrhosis. Gastroenterology 75, 956.Google Scholar
Bloxam, D. L., Tan, J. C. Y. & Parkinson, C. E. (1984). Non-protein bound zinc concentration in human plasma and amniotic fluid measured by ultrafiltration. Clinica Chimica Acta 144, 81–93.Google Scholar
Bloxam, D. L., Williams, N. R., Waskett, R. J. D., Pattinson-Green, P. M., Morarji, Y. & Stewart, S. G. (1989). Maternal zinc during oral iron supplementation in pregnancy: a preliminary study. Clinical Science 76, 59–65.Google Scholar
Bryce-Smith, D. & Hodgkinson, L. (1986). The Zinc Solution. London: Century Arrow.Google Scholar
Buckley, R. A. & Dreosti, I. E. (1984). Radioisotopic studies concerning the efficacy of standard washing procedures for the cleaning of hair before zinc analysis. American Journal of Clinical Nutrition 40, 840–846.Google Scholar
Buerk, C. A., Chandy, M. G., Pearson, E., MacAuly, A. & Soroff, H. S. (1973). Zinc deficiency: effect on healing and metabolism in man. Surgical Forum 24, 101–102.Google Scholar
Bunker, V. W., Hinks, L. J., Stansfield, M. F., Lawson, M. S. & Clayton, B. E. (1987). Metabolic balance studies for zinc and copper in housebound elderly people and the relationship between zinc balance and leukocyte zinc concentrations. American Journal of Clinical Nutrition 46, 353–359.Google Scholar
Castillo-Duran, C., Heresi, G., Fisberg, M. & Oauy, R. (1987). Controlled trial of zinc supplementation during recovery from malnutrition: effects on growth and immune function. American Journal of Clinical Nutrition 45, 602–608.Google Scholar
Crofton, R. W., Clapham, M., Humphries, W. R., Aggett, P. J. & Mills, C. F. (1983). Leucocyte and tissue zinc concentrations in the growing pig. Proceedings of the Nutrition Society 42, 128A.Google Scholar
Dormandy, T. L. (1986). Trace element analysis of hair. British Medical Journal 293, 975–976.Google Scholar
Elia, M., Crozier, C. & Neale, G. (1984). Mineral metabolism during short-term starvation in man. Clinica Chimica Acta 139, 37–45.Google Scholar
Erten, J., Arcasoy, A., Cavdar, A. O. & Cin, S. (1978). Hair zinc levels in healthy and malnourished children. American Journal of Clinical Nutrition 31, 1172–1174.Google Scholar
Everett, G. & Apgar, J. (1984). Effect of low zinc intake on plasma and leukocyte zinc concentration in pregnant ewes. In Trace Element Analytical Chemistry in Medicine & Biology, vol. 3. pp. 695–702 [Bratter, P. and Schramel, P., editors]. Berlin: Walter de Gruyter.Google Scholar
Fell, G. S., Fleck, A., Cuthbertson, D. P., Queen, K., Morrison, D. P., Bessent, R. G. & Husain, S. L. (1973). Urinary zinc levels as an indication of muscle catabolism. Lancet i, 280–282.Google Scholar
Flear, C. T. G., Cooke, W. T. & Quinton, A. (1957). Serum potassium levels as an index of body content. Lancet i, 458–459.Google Scholar
Fredricks, R. E., Tanaka, K. R. & Valentine, W. N. (1964). Variations of human blood cell zinc in disease. Journal of Clinical Investigation 43, 304–315.Google Scholar
Freeland-Graves, J. H., Hendrickson, P. J., Ebangit, M. L. & Snowden, J. Y. (1981). Salivary zinc as an index of zinc status in women fed a low-zinc diet. American Journal of Clinical Nutrition 34, 312–321.Google Scholar
Garvey, J. S. & Chang, C. C. (1981). Detection of circulating metallothionein in rats injected with zinc or cadmium. Science 214, 805–807.Google Scholar
Gibson, R. S., Vanderkooy, P. D. S., MacDonald, A. C., Goldman, A., Ryan, B. A. & Berry, M. (1989). A growth-limiting. mild zinc-deficiency syndrome in some Southern Ontario boys with low height percentiles. American Journal of Clinical Nutrition 49, 1266–1273.CrossRefGoogle ScholarPubMed
Giugliano, R. & Millward, D. J. (1984). Growth and zinc homeostasis in the severely Zn-deficient rat. British Journal of Nutrition 52, 545–560.Google Scholar
Golden, B. E. & Golden, M. H. N. (1981). Plasma zinc, rate of weight gain and the energy cost of tissue deposition in children recovering from severe malnutrition on a cow's milk or soya protein based diet. American Journal of Clinical Nutrition 34, 892–899.Google Scholar
Golub, M. S., Gershwin, M. E., Hurley, L. S., Baly, D. L. & Hendrickx, A. G. (1984). Studies of marginal zinc deprivation in rhesus monkeys. I. Influence on pregnant dams. American Journal of Clinical Nutrition 39, 265–280.Google Scholar
Goode, H. F., Kelleher, J. & Walker, B. E. (1989 a). Zinc concentrations in pure populations of peripheral blood neutrophils, lymphocytes and monocytes. Annals of Clinical Biochemistry 26, 89–95.Google Scholar
Goode, H. F., Kelleher, J., Walker, B. E., Hall, R. I. & Guillou, P. J. (1989 b). Neutrophil zinc is related to the severity of hepatic damage in patients with liver disease. Proceedings of the Nutrition Society 49, 73A.Google Scholar
Goode, H. F., Penn, N. D., Kelleher, J. & Walker, B. E. (1989 c). A critical assessment of leucocyte zinc as an index of Zn status in chronically ill hospitalized elderly patients. Proceedings of the Nutrition Society 49, 71A.Google Scholar
Gvozdanovic, S., Gvozdanovic, D., Crofton, R. W., Aggett, P. J., Mowatt, N. A. G. M. & Brunt, P. W. (1982). Study of zinc kinetics in liver and skeleton in patients with cirrhosis. Nuclear Medicine Communications 3, 127.Google Scholar
Hambidge, K. M. (1988). Assessing the trace element status of man. Proceedings of the Nutrition Society 47, 37–44.Google Scholar
Hambidge, K. M., Krebs, N. F. & Walravens, P. A. (1985). Zinc-deficiency. In Proceedings of the XIII International Congress of Nutrition, pp. 513–516 [Taylor, T. G. and Jenkins, N. K., editors]. London: John Libbey.Google Scholar
Hess, F. M., King, J. C. & Margen, S. (1977). Zinc excretion in young women on low zinc intakes and oral contraceptive agents. Journal of Nutrition 107, 1610–1620.Google Scholar
Jackson, M. J., Jones, D. A. & Edwards, R. H. T. (1981). Zinc excretion as an index of muscle catabolism. Clinical Science 61, 7.Google Scholar
Jackson, M. J., Jones, D. A. & Edwards, R. H. T. (1982). Tissue zinc levels as an index of body zinc status. Clinical Physiology 2, 333–343.Google Scholar
Jacobson, S. G., Meadows, N. J., Keeling, P. W. N. & Thompson, R. P. H. (1986). Rod-mediated retinal dysfunction in cats with zinc depletion: comparison with taurine depletion. Clinical Science 71, 559–564.Google Scholar
Jones, R. B., Keeling, P. W. N., Hilton, P. J. & Thompson, R. P. H. (1981). The relationship between leucocyte and muscle zinc in health and disease. Clinical Science 60, 237–239.Google Scholar
Keeling, P. W. N., Jones, R. B., Hilton, P. J. & Thompson, R. P. H. (1980). Reduced leucocyte zinc in liver disease. Gut 21, 561–564.Google Scholar
Keeling, P. W. N., O'Day, J., Ruse, W. & Thompson, R. P. H. (1982). Zinc deficiency and photoreceptor dysfunction in chronic liver disease. Clinical Science 62, 109–111.Google Scholar
Keeling, P. W. N., Ruse, W., Bull, J., Hannigan, B. & Thompson, R. P. H. (1981). Direct measurement of the hepatointestinal extraction of zinc in cirrhosis and hepatitis. Clinical Science 61, 441–444.Google Scholar
Keen, C. L., Golub, M. S., Gershwin, M. E., Lonnerdal, B. & Hurley, L. S. (1988). Studies of marginal zinc deprivation in rhesus monkeys. III. Use of liver biopsy in the assessment of zinc status. American Journal of Clinical Nutrition 47, 1041–1045.Google Scholar
Keen, C. L., Peters, J. M. & Hurley, L. S. (1989). The effect of valproic acid on 65Zn distribution in the pregnant rat. Journal of Nutrition 119, 607–611.Google Scholar
King, A. B. & Schwartz, R. (1987). Effects of the antituberculous drug ethambutol on zinc absorption, turnover and distribution in rats fed diets marginal and adequate in zinc. Journal of Nutrition 117, 704–708.Google Scholar
Kinlaw, W. B., Levine, A. S., Morley, J. E., Silvis, S. E. & McClain, C. J. (1983). Abnormal zinc metabolism in type II diabetes mellitus. American Journal of Medicine 75, 273–277.Google Scholar
Klevay, L. M., Bistrian, B. R., Fleming, C. R. & Neumann, C. G. (1987). Hair analysis in clinical and experimental medicine. American Journal of Clinical Nutrition 46, 233–236.Google Scholar
Lavis, G. J., Ofci, V. & Bender, D. A. (1986). Differences in the zinc content of different regions of the toe-nail. Proceedings of the Nutrition Society 46, 59A.Google Scholar
Lindh, U. & Johansson, E. (1987). Trace-element determination in individual peripheral blood cells and possible diagnostic applications. Biological Trace Element Research 12, 351–362.CrossRefGoogle ScholarPubMed
Lowe, N. M. & Jackson, M. J. (1989). Plasma 65zinc kinetics in zinc-deficient and endotoxin-treated rats. Proceedings of the Nutrition Society 49, 69A.Google Scholar
Lykken, G. I. (1983). A whole body counting technique using ultralow doses of 59Fe and 65Zn in absorption and retention studies in humans. American Journal of Clinical Nutrition 37, 652–662.CrossRefGoogle ScholarPubMed
McKenzie, J. M. (1978). Alteration of the zinc and copper concentration of hair. American Journal of Clinical Nutrition 31, 470–476.Google Scholar
Meadows, N. J., Cunnane, S. C., Keeling, P. W. N. & Thompson, R. P. H. (1983 a). The diagnosis of nucleated tissue zinc depletion in man and its effect upon pregnancy. In Zinc Deficiency in Human Subjects, [Prasad, A. S., Cavdar, A. O., Brewer, G. J. and Aggett, P. J., editors]. New York: Alan R. Liss.Google Scholar
Meadows, N., Ruse, W., Keeling, P. W. N., Scopes, J. W. & Thompson, R. P. H. (1983 b). Peripheral blood leucocyte zinc depletion in babies with intrauterine growth retardation. Archives of Diseases in Childhood 58, 807–809.Google Scholar
Meadows, N. J., Ruse, W., Smith, M. F., Day, J., Keeling, P. W. N., Scopes, J. W., Thompson, R. P. H. & Bloxam, D. L. (1981). Zinc and small babies. Lancet ii, 1135–1137.Google Scholar
Mikasa, H., Suzuki, Y., Fujii, N. & Nishiyama, K. (1988). Adsorption and elution of metals on hair. Biological Trace Element Research 16, 59–66.Google Scholar
Mills, P. R., Fell, G. S., Bessent, R. G., Nelson, L. M. & Russell, R. I. (1983). A study of zinc metabolism in alcoholic cirrhosis. Clinical Science 64, 527–535.Google Scholar
Milne, D. B., Canfield, W. K., Gallagher, S. K., Hunt, J. R. & Klevay, L. M. (1987). Ethanol metabolism in postmenopausal women fed a diet marginal in zinc. American Journal of Clinical Nutrition 46, 688–693.Google Scholar
Milne, D. B., Ralston, N. V. C. & Wallwork, J. C. (1985 a). Zinc content of blood cellular components and lymph node and spleen lymphocytes in severely zinc-deficient rats. Journal of Nutrition 115, 1073–1078.Google Scholar
Milne, D. B., Ralston, N. V. C. & Wallwork, J. C. (1985 b). Zinc content of cellular components of blood: Methods for cell separation and analysis evaluated. Clinical Chemistry 31, 65–69.Google Scholar
Morrison, S. A., Russell, R. M., Carney, E. A. & Oaks, E. V. (1978). Zinc deficiency: a cause of abnormal dark adaptation in cirrhotics. American Journal of Clinical Nutrition 31, 276–281.Google Scholar
Nakamura, T., Higashi, A., Takano, S., Akagi, M. & Matsuda, I. (1988). Zinc clearance correlates with clinical severity of Crohn's disease. A kinetic study. Digestive Diseases and Sciences 33, 1520–1524.Google Scholar
Pai, L. H. & Prasad, A. S. (1988). Cellular zinc in patients with diabetes mellitus. Nutrition Research 8, 889–897.Google Scholar
Paton, A. (1981). Mission to Belsen 1945. British Medical Journal 283, 1656–1659.Google Scholar
Pironi, L., Miglioli, M., Cornia, G. L., Ursitti, M. A., Tolomelli, M., Piazzi, S. & Barbara, L. (1987). Urinary zinc excretion in Crohn's disease. Digestive Diseases and Sciences 32, 358–362.Google Scholar
Prasad, A., Meftah, S., Abdallah, J., Kaplan, J., Brewer, G. J., Bach, J. F. & Dardenne, M. (1988). Serum thymulin in human zinc deficiency. Journal of Clinical Investigation 82, 1202–1210.Google Scholar
Prasad, A., Miale, A., Farid, Z., Sandstead, H. H. & Schulert, A. R. (1963). Zinc metabolism in patients with the syndrome of iron deficiency anemia, hepatosple nomegaly. dwarfism, and hypogonadism. Journal of Laboratory and Clinical Medicine 61, 537–549.Google Scholar
Prasad, A. S., Rabbani, P., Abbasii, A., Bowersox, E. & Fox, M. R. S. (1978). Experimental zinc deficiency in humans. Annals of Internal Medicine 89, 483–490.Google Scholar
Robertson, A., Morrison, J. N., Wood, A. M. & Bremner, I. (1989). Effects of iron deficiency on metallothionein-I concentrations in blood and tissues of rats. Journal of Nutrition 119, 439–445.Google Scholar
Sato, M., Mehra, R. K. & Bremner, I. (1984). Measurement of plasma metallothionein-I in the assessment of the zinc status of zinc-deficient and stressed rats. Journal of Nutrition 114, 1683–1689.Google Scholar
Senapati, A. (1986). Zinc in growth and healing. PhD Thesis, London.Google Scholar
Senapati, A., Jenner, G. & Thompson, R. P. H. (1989). Zinc in the elderly. Quarterly Journal of Medicine 70, 81–87.Google Scholar
Simmer, K., Carlsson, L. & Thompson, R. P. H. (1986). Interaction of cadmium and zinc in pregnancy. Clinical Science 70, 50–51P.Google Scholar
Simmer, K., Khanums, L. C. & Thompson, R. P. H. (1988). Nutritional rehabilitation in Bangladesh the importance of zinc. American Journal of Clinical Nutrition 47, 1036–1040.Google Scholar
Simmer, K., Pearson, T. C., Wheeler, M. J. & Thompson, R. P. H. (1987). Zinc status in polycythaemia. European Journal of Haematology 38, 433–436.Google Scholar
Simmer, K. & Thompson, R. P. H. (1985). Maternal zinc and intrauterine growth retardation. Clinical Science 68, 395–399.Google Scholar
Solomons, N. W. (1979). On the assessment of zinc and copper nutriture in man. American Journal of Clinical Nutrition 32, 856–871.Google Scholar
Sullivan, J. F., Jetton, M. M. & Burch, R. E. (1979). A zinc tolerance test. Journal of Laboratory and Clinical Medicine 93, 485–492.Google Scholar
Tuttle, S., Aggett, P. J., Campbell, D. & MacGillivray, I. (1985). Zinc and copper nutrition in human pregnancy: a longitudinal study in normal primigravidae and in primigravidae at risk of delivering a growth retarded baby. American Journal of Clinical Nutrition 41, 1032–1041.Google Scholar
Van den Hamer, C. J. A., Kroon, J. J. & Tjioe, P. S. (1987). An oral zinc loading test using an enriched stable zinc isotope. In Trace Element Analytical Chemistry in Medicine & Biology, vol. 4, pp. 247–253 [Bratter, P. and Schramel, P., editors]. Berlin: Walter de Gruyter.Google Scholar
Wallwork, J. C. (1987). Appraisal of the methodology and applications for measurement of the zinc content of blood components as indicators of zinc status. Biological Trace Element Research 12, 335–350.Google Scholar
Weismann, K. & Hoyer, H. (1985). Serum alkaline phosphatase and serum zinc levels in the diagnosis and exclusion of zinc deficiency in man. American Journal of Clinical Nutrition 41, 1214–1219.Google Scholar
Wells, J. L., James, D. K., Luxton, R. & Pennock, C. A. (1987). Maternal leucocyte zinc deficiency at start of third trimester as a predictor of fetal growth retardation. British Medical Journal 294, 1054–1056.CrossRefGoogle ScholarPubMed
Whitehouse, R. C., Prasad, A. S. & Cossack, Z. T. (1983). Determination of ultrafiltrable zinc in plasma by flameless atomic absorption spectrophotometry. Clinical Chemistry 29, 1974–1977.Google Scholar
Widdowson, E. M., McCance, R. A. & Spray, C. M. (1951). The chemical composition of the human body. Clinical Science 10, 113–125.Google Scholar
Yunice, A. A., King, R. W., Kraikitpanitch, S., Haygood, C. C. & Lindrman, R. D. (1978). Urinary zinc excretion following infusions of zinc sulfate, cysteine. histidine, or glycine. American Journal of Physiology 235, F40–15.Google Scholar