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Vaccine against scabies: necessity and possibility

Published online by Cambridge University Press:  28 January 2014

XIAOSONG LIU ,
SHELLEY WALTON  and
KATE MOUNSEY
XIAOSONG LIU*
Affiliation:
Inflammation and Healing Research Cluster, Faculty of Science, Health, Education and Engineering, School of Health and Sport Sciences, University of Sunshine Coast, Locked Bag 4, Marcoochydore DC, QLD 4558, Australia
SHELLEY WALTON
Affiliation:
Inflammation and Healing Research Cluster, Faculty of Science, Health, Education and Engineering, School of Health and Sport Sciences, University of Sunshine Coast, Locked Bag 4, Marcoochydore DC, QLD 4558, Australia
KATE MOUNSEY
Affiliation:
Inflammation and Healing Research Cluster, Faculty of Science, Health, Education and Engineering, School of Health and Sport Sciences, University of Sunshine Coast, Locked Bag 4, Marcoochydore DC, QLD 4558, Australia
*
* Corresponding author: Inflammation and Healing Research Cluster, Faculty of Science, Health, Education and Engineering, School of Health and Sports Sciences, University of Sunshine Coast, Sippy Downs, QLD, Australia. E-mail: [email protected]
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Summary

Scabies is an infectious disease that is endemic in poorly resourced communities, and also common in industrialized countries. Although the disease, which is caused by infestation of Sarcoptes scabiei, is generally mild, the need for a vaccine against S. scabiei is proposed. The immunological mechanisms that control S. scabiei infection are discussed and the current status of scabies vaccine development reviewed. Future directions for scabies vaccine development are also addressed.

Keywords

Scabiesprotective immune responsesvaccine
Type
Review Article
Information
Parasitology , Volume 141 , Issue 6 , May 2014 , pp. 725 - 732
Copyright
Copyright © Cambridge University Press 2014 

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