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Trypanosoma evansi in naturally infected Dromedary Camels: lipid profile, oxidative stress parameters, acute phase proteins and proinflammatory cytokines

Published online by Cambridge University Press:  18 February 2016

S. M. EL-BAHR  and
W. M. EL-DEEB
S. M. EL-BAHR*
Affiliation:
Department of Physiology, Biochemistry and Pharmacology (Biochemistry), College of Veterinary Medicine and Animal Resources, King Faisal University, Al-Ahsa, Saudi Arabia Department of Biochemistry, Faculty of Veterinary Medicine, Alexandria University, Egypt
W. M. EL-DEEB
Affiliation:
Department of Clinical studies, College of Veterinary Medicine and Animal Resources, King Faisal University, Al-Ahsa, Saudi Arabia Department of Veterinary Medicine, Infectious Diseases and Fish Diseases, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt
*
* Corresponding author:Department of Physiology, Biochemistry and Pharmacology (Biochemistry), College of Veterinary Medicine and Animal Resources, King Faisal University, Al-Ahsa, Saudi Arabia. E-mail: [email protected]
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Summary

Additional biomarkers are essential for control of Trypanosoma evansi (T. evansi) infection in dromedary camels. Two groups of 30 camels each, one naturally infected with T. evansi and other normal healthy were executed. The basis for the infection was the positive findings of clinical examination, blood smears and latex agglutination test. Blood samples of both groups and its harvested serum were used for the estimation of present serobiochemical parameters. The present findings revealed significant decrease (P ⩽ 0·05) in triacylglycerol, cholesterol, high density lipoprotein cholesterol with significant increase (P ⩽ 0·05) in low density lipoprotein cholesterol, beta hydroxyl butyric acids, non-esterified fatty acids, haptoglobin, serum amyloid A, ceruloplasmin, fibrinogen, interleukins, tumour necrosis factor-α, interferon gamma, malondialdehyde, superoxide dismutase, reduced glutathione and catalase of infected camels compared with the control. The present study suggests lipid profile, acute phase proteins, proinflammatory cytokines and oxidative stress parameters as biomarkers for T. evansi infection in camels.

Keywords

Camelstrypanosomosisacute phase proteinscytokinesoxidative stress
Type
Research Article
Information
Parasitology , Volume 143 , Issue 4 , April 2016 , pp. 518 - 522
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Copyright
Copyright © Cambridge University Press 2016 

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