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Transplantation of adult Trichinella spiralis between hosts: worm survival and immunological characteristics of the host–parasite relationship

Published online by Cambridge University Press:  06 April 2009

M. W. Kennedy ,
D. Wakelin  and
Margaret M. Wilson
M. W. Kennedy
Affiliation:
Department of Zoology and Wellcome Laboratories for Experimental Parasitology, University of Glasgow
D. Wakelin
Affiliation:
Department of Zoology and Wellcome Laboratories for Experimental Parasitology, University of Glasgow
Margaret M. Wilson
Affiliation:
Department of Zoology and Wellcome Laboratories for Experimental Parasitology, University of Glasgow
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Summary

A technique for the transplantation of Trichinella spiralis worms directly into the host intestine is described. Infections established by the direct transfer of adult worms were essentially normal both in terms of their survival and reproduction and in their stimulation of, and susceptibility to, host immune responses. Worms transplanted from NIH mouse donors at intervals after infection had an equal ability to survive in the recipient, even when taken from the donor shortly before or during the process of worm expulsion, showing that expulsion does not require worms to be irreversibly damaged. It was noted, however, that after 7 days in the donor the ability of the worm to reproduce in the recipient was temporarily impaired.

Type
Research Article
Information
Parasitology , Volume 78 , Issue 2 , April 1979 , pp. 121 - 130
Copyright
Copyright © Cambridge University Press 1979

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References

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