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Transfer of Eimeria apionodes from wood mice (Apodemus sylvaticus) to laboratory mice (Mus musculus)

Published online by Cambridge University Press:  06 April 2009

S. A. M. Ibrahim  and
F. Nowell
S. A. M. Ibrahim
Affiliation:
Department of Pure and Applied Zoology, School of Animal and Microbial Sciences, University of Reading, Whiteknights, P.O.Box 228, Reading, Berkshire RG6 2AJ
F. Nowell
Affiliation:
Department of Pure and Applied Zoology, School of Animal and Microbial Sciences, University of Reading, Whiteknights, P.O.Box 228, Reading, Berkshire RG6 2AJ
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Abstract

Transfer of Eimeria apionodes from wood mice directly into untreated laboratory mice was unsuccessful but transfer into corticosteroid-treated animals produced an oocyst output, about 1000 times less than that observed from wood mice after a similar inoculum. Repeated passage through corticosteroid-treated laboratory mice resulted in a line adapted to survival in untreated animals. This line was compared with the parent strain maintained in wood mice and some features of the oocyst output patterns, notably the pre-patent period, appeared to be controlled by the host species. The oocyst production of each population was higher in the host species to which it was adapted than in the other host species (P > 0·001). Once adapted to laboratory mice, the line produced insignificantly different levels of oocysts in corticosteroid-treated and untreated animals (P > 0·05).

Keywords

Eimeria apionodesApodemus sylvaticushost specificityhydrocortisone
Type
Research Article
Information
Parasitology , Volume 103 , Issue 2 , October 1991 , pp. 179 - 183
Copyright
Copyright © Cambridge University Press 1991

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