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Schistosoma mansoni: patterns of codon usage and bias

Published online by Cambridge University Press:  06 April 2009

J. T. Ellis  and
D. A. Morrison
J. T. Ellis
Affiliation:
School of Biological and Biomedical Sciences, University of Technology Sydney, Westborne Street, Gore Hill, NSW 2065, Australia
D. A. Morrison
Affiliation:
School of Biological and Biomedical Sciences, University of Technology Sydney, Westborne Street, Gore Hill, NSW 2065, Australia
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Extract

Codon usage and bias has been examined in 20 genes of Schistosoma mansoni. Significant heterogeneity was detected in the patterns of codon usage and bias among genes by metric multidimensional scaling and three general indictors of bias (GC3S, Nc and B). In keeping with observations on sporozoan parasites, codon usage bias was observed to be dependent on the overall base composition of the genes analysed, which in turn was reflected in the types of codons that were over or under-represented in the sequences.

Keywords

Schistosoma mansonicodon usagebias
Type
Research Article
Information
Parasitology , Volume 110 , Issue 1 , January 1995 , pp. 53 - 60
Copyright
Copyright © Cambridge University Press 1995

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