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Researches on the Intestinal Protozoa of Monkeys and Man. IV. An experimental study of the Histolytica-like species of Entamoeba living naturally in Macaques

Published online by Cambridge University Press:  06 April 2009

Clifford Dobell
Affiliation:
National Institute for Medical Research, London, N.W. 3.

Extract

Nine attempts to infect kittens directly with E. histolytica macacorurn by means of amoebae (per anum) or cysts (per os) in the faeces of 2 M. sinicus (Polo and Susanna) and 1 M. rhesus (Jacko), were wholly unsuccessful. Four similar experiments with cysts (per os) from another M. sinicus (Bonar) gave 2 positive (Kittens 28 and 31) and 2 negative results.

Attempts to transmit strains of E. histolytica macacorum from one species of Macacus to another have been uniformly successful.

A strain (D.) of E. histolytica, derived from a man suffering from acute amoebic dysentery, has been cultivated in vitro continuously for 5½ years.

(i) The fact has been confirmed that strains of E. histolytica which, when newly isolated, are infective for kittens, may lose this infectivity after continued cultivation in vitro.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1931

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