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Published online by Cambridge University Press: 06 April 2009
The prophylaxis of plasmodial infections, by means of drugs in general, and by plasmoquine in particular, has been the subject of two reports to which we wish to refer: (1) by James, Nicol and Shute (1931), and (2) by Swellengrebel and de Buck (1931). The authors of report (1) obtained complete success by the use of 0·06 g. of plasmoquine before, and daily for 6 days after, the bite of infected mosquitoes, while the authors of report (2), giving 0·03 g. of the drug daily, had but poor success, notwithstanding Ottolenghi and Brotzu (1929), whom they cite, having reported that 0·02 g. daily with 0·25 g. of quinine was a good practical prophylactic.