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Progress in paediatric parasitology: a preface to a topic focusing on ever younger subjects

Published online by Cambridge University Press:  16 September 2011

J. RUSSELL STOTHARD ,
PETER CHIODINI  and
MARK BOOTH
J. RUSSELL STOTHARD*
Affiliation:
Centre for Tropical and Infectious Diseases, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, United Kingdom
PETER CHIODINI
Affiliation:
Hospital for Tropical Diseases, Mortimer Market, London, WC1E 6JD, United Kingdom
MARK BOOTH
Affiliation:
Wolfson Research Institute, University of Durham, Stockton-on-Tees, TS17 6BH, United Kingdom
*
*Corresponding author: Tel: + 44 151 7053724; E-mail: [email protected]
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Summary

Without realizing it perhaps, the research activities of many parasitologists are often focused upon the study of parasites most commonly found in children. Though there is little recognition of paediatric parasitology as a separate topic within medical parasitology, with the global interest in promotion of maternal and child health, alleviation of diseases associated with poverty and requirements of ‘child-sized’ medicines, a more formal consideration is now timely. Recent research, for example, has highlighted that defining precisely the ‘first-age’ at which parasites interfere with a child's health, or normal developmental processes, is being revised. Attention is now drawn towards ever younger subjects, for parasites have the capacity to also influence the health of the foetus within the in utero environment, altering immune-development. These subtle, yet evolutionary profound interactions perhaps manifest themselves as to why some children are more prone to infection(s), develop overt disease and sadly die while others do not. Here, we address the growing importance of paediatric parasitology and its applications within disease control strategies as highlighted in the 2010 Autumn Symposium of the British Society of Parasitology.

Keywords

millennium development goalsmaternal and child healthinfancychildhoodadolescencediseasesparasites
Type
Research Article
Information
Parasitology , Volume 138 , Special Issue 12: Symposia of the British Society for Parasitology Volume 47 , October 2011 , pp. 1453 - 1458
Copyright
Copyright © Cambridge University Press 2011

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References

REFERENCES

Black, R. E., Cousens, S., Johnson, H. L., Lawn, J. E., Rudan, I., et al. (2010). Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet 375, 1969–1987.CrossRefGoogle ScholarPubMed
Breiger, W. (2011). Malaria and HIV: demystifying the often misunderstood relationship. Africa Health, (July), 14–16.Google Scholar
Cox, F. E. G. (2009). George Henry Falkiner Nuttall and the origins of parasitology and Parasitology. Parasitology 136, 1389–1394.CrossRefGoogle Scholar
de Onis, M., Onyango, A. W., Borghi, E., Siyam, A., Nishida, C. and Siekmann, J. (2007). Development of a WHO growth reference for school-aged children and adolescents. Bulletin of the World Health Organisation 85, 649–732.Google ScholarPubMed
Djuardi, Y., Wammes, L. J., Supali, T., Sartono, E. and Yazdanbakhsh, M. (2011). Immunological footprint: the development of a child's immune system in environments rich in microorganisms and parasites. Parasitology 138, 1508–1518.CrossRefGoogle Scholar
Elliott, A. M., Ndibazza, J., Mpairwe, H., Muhangi, L., Webb, E. L., Kizito, D., Mawa, P., Tweyongyere, R. and Muwanga, M. for the Entebbe Mother and Baby Study Team (2011). Treatment with anthelmintics during pregnancy: what gains and what risks for the mother and child? Parasitology 138, 1499–1507.CrossRefGoogle ScholarPubMed
Fenwick, A., Webster, J. P., Bosque-Oliva, E., Blair, L., Fleming, F. M., Zhang, Y., Garba, A., Stothard, J. R., Gabrielli, A., Clements, A. C. A., Kabatereine, N. B., Toure, S., Dembele, R., Nyandindi, U., Mwansa, J. and Koulounari, A. (2009). The Schistosomiasis Control Initiative (SCI): rationale, development and implementation from 2002–2008. Parastiology 136, 1719–1730.Google Scholar
Gould, S. J. (1981). The mismeasure of man. New York, W. W. Norton.Google Scholar
Green, H. K., Sousa-Figueiredo, J. C., Basánêz, M-G., Betson, M., Kabatereine, N. B., Fenwick, A. and Stothard, J. R. (2011). Anaemia in Ugandan preschool-aged children: the relative contribution of intestinal parasites and malaria. Parasitology 138, 1534–1545.Google Scholar
Halwindi, H., Magnussen, P., Siziya, S., Handema, R., Meyrowitsch, D. W. and Olsen, A. (2011). Impact of community-directed treatment on soil-transmitted helminth infections in children aged 12 to 59 months in Mazabuka Dustrict, Zambia. Parasitology 138, 1578–1585.CrossRefGoogle Scholar
Higón, M., Cowan, G., Nausch, N., Cavanagh, D., Oleaga, A., Toledo, R., Stothard, J. R., Antúnez, O., Marcilla, A., Burchmore, R. and Mutapi, F. (2011). Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echinostoma caproni. Parasitology 138, 1607–1619.CrossRefGoogle ScholarPubMed
Imai, N., Rujeni, N., Nausch, N., Bourke, C., Appleby, L., Cowan, G., Gwisai, R., Midzi, N., Cavanagh, D., Mduluza, T., Taylor, D. and Mutapi, F. (2011). Exposure, infection, systemic cytokine and antibody responses in young children concurrently exposed to schistosomiasis and malaria. Parasitology 138, 1519–1533.CrossRefGoogle ScholarPubMed
Keiser, J., Ingram, K. and Utzinger, J. (2011). Antiparasitic drugs for paediatrics: systematic review, formulations, pharmacokinetics, safety, efficacy and implications for control. Parasitology 138, 1620–1632.CrossRefGoogle ScholarPubMed
Kelly, P. (2011). Treatment and prevention of cryptosporidiosis: what options are there for a country like Zambia? Parasitology 138, 1488–1491.Google Scholar
Namwanje, H., Kabatereine, N. B. and Olsen, A. (2011). The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1–4 years in Uganda. Parasitology 138, 1586–1592.Google Scholar
Medlin, C. A., Chowdhury, M., Jamison, D. T. and Measham, A. (2006). Improving the health of populations: Lessons of experience. In “Disease control priorities in developing countries”. 2nd edition. Jamison, D. T., Breman, J. G., Measham, A. R., et al. , editors. Washington (DC): World Bank.Google Scholar
Naidoo, I. and Roper, C. (2011). Drug resistance maps to guide intermittent preventive treatment of malaria in African infants. Parasitology 138, 1469–1479.CrossRefGoogle ScholarPubMed
Odiere, M. R., Opisa, S., Odhiambo, G., Jura, W. G. Z. O., Ayisi, J. M., Karanja, D. M. S. and Mwinzi, P. N. (2011). Geographical distribution of schistosomiasis and soil-transmitted helminths among school children in informal settlements in Kisumu City, Western Kenya. Parasitology 138, 1569–1577.CrossRefGoogle ScholarPubMed
Sangare, L. R., Herrin, B. R., John-Stewart, G. and Walson, J. L. (2011). Species-specific treatment effects of helminth/HIV-1 co-infection: a systematic review and meta-analysis. Parasitology 138, 1546–1558.CrossRefGoogle ScholarPubMed
Shenoy, R. K. and Bockarie, M. J. (2011). Lymphatic filariasis in children: clinical features, infections burdens and future prospects for elimination. Parasitology 138, 1559–1568.CrossRefGoogle ScholarPubMed
Stothard, J. R., Sousa-Figueiredo, J. C., Betson, M., Green, H. K., Seto, E. Y. W., Garba, A., Sacko, M., Mutapi, F., Vaz Nery, S., Amin, M. A., Mutumba-Nakalembe, M., Navaratnam, A., Fenwick, A., Kabatereine, N. B., Gabrielli, A. F. and Montresor, A. (2011). Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children. Parasitology 138, 1593–1606.CrossRefGoogle ScholarPubMed
Sutherland, C. J., Babiker, H., Mackinnon, M. J., Ranford-Cartwright, L. and El Sayed, B. B. (2011). Rational deployment of antimalarial drugs in Africa: should the first-line combination drugs be reserved for paediatric malaria cases? Parasitology 138, 1459–1468.Google Scholar
Verweij, J. J. and van Leishout, L. (2011). Intestinal parasitic infections in an industrialized country: a new focus on children with better DNA-based diagnostics. Parasitology 138, 1492–1498.Google Scholar
Wastling, S. L., Picozzi, K., Wamboga, C., Von Wissmann, B., Amongi-Accup, C., Wardrop, N. A., Stothard, J. R., Kakembo, A. and Welburn, S. C. (2011). Latent Trypanosoma brucei gambiense foci in Uganda: a silent epidemic in children and adults? Parasitology 138, 1480–1487.CrossRefGoogle ScholarPubMed
WHO (2010). World Malaria Report 2010. WHO: Geneva.Google Scholar