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A preliminary study of the nature of infection and immunity in chickens given an attenuated line of Eimeria acervulina

Published online by Cambridge University Press:  06 April 2009

V. McDonald ,
S. Ballingall  and
M. W. Shirley
V. McDonald
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PE17 2DA
S. Ballingall
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PE17 2DA
M. W. Shirley
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PE17 2DA
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Summary

The Houghton (H) strain of Eimeria acervulina was attenuated by serial passage through chickens of the first oocysts produced during infection. This selection pressure resulted in a reduction in the pre-patent period of the parasite, shown to be due to the selection of a line predominantly with only 3 instead of 4 generations of schizonts. The precocious line had a reproductive potential much lower than that of the parent strain and it was significantly less pathogenic. Chickens given oocysts of the precocious line were almost completely immune to challenge with the Houghton strain.

Type
Research Article
Information
Parasitology , Volume 84 , Issue 1 , February 1982 , pp. 21 - 30
Copyright
Copyright © Cambridge University Press 1982

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