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Ovine hydatidosis: some immunological characteristics of the seronegative host

Published online by Cambridge University Press:  06 April 2009

D. G. Judson ,
J. B. Dixon ,
M. J. Clarkson  and
J. Pritchard
D. G. Judson
Affiliation:
Department of Veterinary Pathology, University of Liverpool, P.O. Box 147, Liverpool 169 3BX
J. B. Dixon
Affiliation:
Department of Veterinary Pathology, University of Liverpool, P.O. Box 147, Liverpool 169 3BX
M. J. Clarkson
Affiliation:
Division of Farm Animal Medicine, Department of Veterinary Clinical Science, University of LiverpoolVeterinary Field Station, Leahurst, Neston, S. Wirral L64 7TE
J. Pritchard
Affiliation:
Division of Farm Animal Medicine, Department of Veterinary Clinical Science, University of LiverpoolVeterinary Field Station, Leahurst, Neston, S. Wirral L64 7TE
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Extract

The immune status of a group of sheep naturally infected with hydatid cysts was investigated. Low specific anti-hydatid antibody (Sab) titres and negative results in intradermal and leucocyte migration tests occurred in hosts with high hydatid antigen-stimulated lymphocyte transformation(LT). Total(non-specific) IgG was elevated in infected sheep and was positively correlated with LT. Circulating hydatid antigen (cAg) was detectable in some infected sheep, but not in all of those with low Sab. Relationships between eAg, Sab and immune complex levels suggest that most eAg is present in immune complexes.

Type
Research Article
Information
Parasitology , Volume 91 , Issue 2 , October 1985 , pp. 349 - 357
Copyright
Copyright © Cambridge University Press 1985

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References

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