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On the Persistence of Eosinophilia, and on Immune Reactions in Human Trichinosis, Several Years after Recovery

Published online by Cambridge University Press:  06 April 2009

Hans Theiler ,
Donald L. Augustine  and
Wesley W. Spink
Hans Theiler
Affiliation:
Department of Comparative Pathology, Medical School and School of Public Health, Harvard University
Donald L. Augustine
Affiliation:
Department of Comparative Pathology, Medical School and School of Public Health, Harvard University
Wesley W. Spink
Affiliation:
Department of Comparative Pathology, Medical School and School of Public Health, Harvard University
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Extract

Following a brief historical introduction, the results of differential counts, precipitin tests and skin reactions on seven cases of trichinosis 4–9 years after recovery are presented. Eosinophile counts ranging from 2 to 7 per cent. were encountered, but the number of cases studied does not warrant any conclusion being drawn. Positive precipitin tests and intradermal reactions were encountered in cases up to 7 years after infection. The findings are discussed, together with a consideration of the pertinent literature, and the importance of the skin reaction and precipitin tests as aids to diagnosis are emphasised in conjunction with due consideration of the history and symptomatology. It is affirmed that the tests have proved of value in establishing a diagnosis in mild cases.

It is a pleasure to acknowledge our indebtedness to Dr George R. Minot, who made the records of the hospital available to us, and to Dr W. D. Sutliff, whose continued interest and ready co-operation greatly facilitated our work.

Type
Research Article
Information
Parasitology , Volume 27 , Issue 3 , July 1935 , pp. 345 - 354
Copyright
Copyright © Cambridge University Press 1935

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References

REFERENCES

Augustine, D. L. and Theiler, Hans (1932). Precipitin and skin tests as aids in diagnosing trichinosis. Parasitology, 24 60–86.Google Scholar
Bachman, G. W. (1928). A precipitin test in experimental trichiniasis. J. prev. Med., Baltimore, 2, 35.Google Scholar
Bachman, G. W. (1928 a). An intradermal test in experimental trichiniasis. J. prev. Med. 2, 513.Google Scholar
Bachman, G. W., Molina, R. Rodriguez and Gonzalez, J. O. (1934). Anomalous and non-specific reactions with Trichinella spiralis antigen in relation to other disease conditions. Amer. J. Hyg. 20 415–23.Google Scholar
Brown, T. R. (1897). Studies on trichinosis. Johns Hopk. Hosp. Bull. 8 79–81.Google Scholar
Brown, T. R. (1898). Studies on trichinosis, with especial reference to the increase of the eosinophile cells in the blood and muscle, the origin of these cells and their diagnostic importance. J. exp. Med. 3 315–48.Google Scholar
Brown, T. R. (1898 a). A note on the duration of eosinophilia in trichinosis. Boston med. surg. J. 139, 218.Google Scholar
Brown, T. R. (1899). The diagnosis of trichinosis by means of the great increase of the eosinophiles in the blood; report of fourth case. Med. News, N.Y., 74 12–14.Google Scholar
Cabot, R. C. (1897). The diagnosis of trichinosis. Boston med. surg. J. 137, 676.Google Scholar
Ducas, R. (1921). L'immunité dans la trichinose. Thèse. Paris: Jouve et Cie.Google Scholar
Friedlander, R. D. (1934). The present status of the diagnostic intradermal test for human trichiniasis. Amer. J. med. Sci. 188, 121.Google Scholar
Hunter, S. W. (1931). Human Trichinella spiralis infections and the Bachman precipitin test. Amer. J. Hyg. 13, 311.Google Scholar
Kilduffe, R. A. (1933). Bachman intradermal reaction in human trichinosis. Amer. J. med. Sci. 186 802–8.Google Scholar
Maternowska, Irena (1933). Intradermale Hautreaktion bei Trichinose. Zbl. Bakt. Abt. 1, Orig. 129 284–301.Google Scholar
McCoy, O. R. (1931). Immunity of rats to reinfection with Trichinella spiralis. Amer. J. Hyg. 14, 484.Google Scholar
McCoy, O. R., Miller, J. J. and Friedlander, R. D. (1933). The use of an intradermal test in the diagnosis of trichiniasis. J. Immunol. 24 1–23.Google Scholar
Osler, W. (1899). The clinical features of sporadic trichinosis. Amer. J. med. Sci. 117 251–65.Google Scholar
Queen, F. B. (1931). The prevalence of human infection with Trichinella spiralis. J. Parasit. 18, 128.Google Scholar
Riley, W. A. and Scheifley, C. H. (1934). Trichinosis of man a common infection. J. Amer. med. Ass. 102 1217–18.Google Scholar
Schleip, K. (1904). Die Homberger Trichinosisepidemie und die für die Trichinosis pathognomische Eosinophilie. Dtsch. Arch. klin. Med. 80 1–38.Google Scholar
Spink, W. W. (1934). The effects of vaccines, bacterial and parasitic infections upon eosinophilia in trichinous animals. Arch. intern. Med. 54 805–17.Google Scholar
Spink, W. W. and Augustine, D. L. (1934). The diagnosis of trichinosis: with especial reference to skin and precipitin test. J. Amer. med. Ass. (in press).Google Scholar
Stäubli, C. (1909). Trichinosis. Wiesbaden: Bergmann.Google Scholar
Stoll, H. F. (1929). Trichinosis. J. Amer. med. Ass. 92, 791.Google Scholar
Thayer, W. S. (1897). On the increase of the eosinophile cells in the circulating blood in trichinosis. Lancet, ii, 787–8.Google Scholar
Trawinski, A. and Maternowska, I. (1934). Über Präcipitationsreaktion bei Trichinose. Zbl. Bakt. Abt. 1, Orig. 131 10–18.Google Scholar
Weindrach, G. (1929). Das Blutbild und die Eosinophilie bei Trichinose. Folia haemat., Lpz., 38 380–4.Google Scholar
Williams, H. U. (1901). The frequency of trichinosis in the United States. J. med. Res. 6 64–83.Google Scholar