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Nuclear size and DNA content in host cells during first-generation schizogony of Eimeria zuernii

Published online by Cambridge University Press:  06 April 2009

J. pasternak ,
M. A. Fernando ,
P. H. G. Stockdale  and
D. Weber
J. pasternak
Affiliation:
Department of Biology, University of Waterloo, waterloo, Ontario, Canada, N2L 3G1.
M. A. Fernando
Affiliation:
Department of pathology, University of Guelph, Guelph, Ontario, Canada, N2G 2W2.
P. H. G. Stockdale
Affiliation:
Animal Diseases Research Institute (W), P. O. Box 640, Lethbridge, Alberta, Canada.
D. Weber
Affiliation:
Department of Biology, University of Waterloo, waterloo, Ontario, Canada, N2L 3G1.
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Extract

The response of intestinal host-cell nuclei of calves infected with Eimeria zuernii 6 and 8 days post-infection was examined using Feulgen-DNA microspectrophotometry. The results show that nuclear hypertrophy is dissociated from DNA replication. In the light of previous work (Fernando, Pasternak, Barrell & Stockdale, 1974) it is surmised that the specificity of infection of cells by E. zuernii is not stringent, with the major target being non-proliferative cells. At most, 20% of the first-generation schizonts develop within cells that would have had proliferative potential and as a result some non-scheduled DNA synthesis occurs.

Type
Research Article
Information
Parasitology , Volume 74 , Issue 2 , April 1977 , pp. 199 - 203
Copyright
Copyright © Cambridge University Press 1977

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