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Negative effect on early post-implantation pregnancy and progesterone levels in mice infected with the intestinal trematode Echinostoma caproni

Published online by Cambridge University Press:  06 April 2009

E. Bindseil  and
J. Hau
E. Bindseil
Affiliation:
Department of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark
J. Hau
Affiliation:
Department of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark
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Extract

Infection in mice (BALB/cABom) with the intestinal trematode Echinostoma caproni had a negative influence on pregnancy. The effect of the infection set in immediately following implantation (day 5 of pregnancy) resulting in fewer foetuses being present in infected mice on day 9 than in the controls. Ovulation, fertilization of eggs, and implantation itself were obviously not impaired. The infected mice had significantly lower serum progesterone levels on day 5 of pregnancy than the non-infected controls. It is speculated that the progesterone levels in the infected female mice were too low to secure early post-implantation gestation.

Keywords

Echinostoma capronimicepregnancyprogesterone
Type
Research Article
Information
Parasitology , Volume 102 , Issue 3 , June 1991 , pp. 387 - 390
Copyright
Copyright © Cambridge University Press 1991

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