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Milk-borne infection of rats with Strongyloides ratti and Nippostrongylus brasiliensis

Published online by Cambridge University Press:  06 April 2009

Peter A. G. Wilson ,
Maureen Gentle  and
Douglas S. Scott
Peter A. G. Wilson
Affiliation:
Department of Zoology, University of Edinburgh, Scotland
Maureen Gentle
Affiliation:
Department of Zoology, University of Edinburgh, Scotland
Douglas S. Scott
Affiliation:
Department of Zoology, University of Edinburgh, Scotland
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Summary

The numbers of mature worms which developed in young rats after their mothers were injected with 4000 L3 late in lactation were 1% (Nippostrongylus brasiliensis) and 24% (Strongyloides ratti) of the dose administered. The low value for N. brasiliensis validates the conclusion that milk is a real and important vehicle for infection in S. ratti since possible errors from skin invasion of the young would have been common to both species.

The level of mature S. ratti infection in lactating mothers in this experiment was negligible, 97–99% of the adult worms appearing in the offspring.

These results may indicate that the milk route is possible with N. brasiliensis even though it is quantitatively insignificant.

Type
Research Article
Information
Parasitology , Volume 72 , Issue 3 , June 1976 , pp. 355 - 360
Copyright
Copyright © Cambridge University Press 1976

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References

Abadie, S., (1963). The life cycle of Strongyloides ratti. Journal of Parasitology 49, 241–8.CrossRefGoogle ScholarPubMed
Biswas, E. R. I., (1961). Selective secretion of circulating antibodies in the milk of the rat. Nature, London 192, 883–4.CrossRefGoogle ScholarPubMed
Connan, R. M., (1970). The effect of host lactation on the self-cure of Nippostrongylus brasiliensis in rats. Parasitology 61, 27–33.CrossRefGoogle Scholar
Connan, R. M., (1973). The immune response of the lactating rat to Nippostrongylus brasiliensis. Immunology 25, 261–7.Google ScholarPubMed
Cowtb, A. T., & Tindal, J. S., (1971). The Physiology of Lactation. London: Edward Arnold.Google Scholar
Crofton, H. D., (1971). A quantitative approach to parasitism. Parasitology 62, 179–93.CrossRefGoogle Scholar
Dineen, J. K., & Kelly, J. D., (1972). The suppression of rejection of Nippostrongylus brasiliensis in lactating rats: the nature of the immunological defect. Immunology 22, 1–12.Google ScholarPubMed
Haley, A. J., (1962). The biology of the rat nematode, Nippostrongylus brasiliensis (Travassos, 1914). II. Preparasitic stages and development in the laboratory rat. Journal of Parasitology 48, 13–23.CrossRefGoogle Scholar
Kelly, J. D., & Dineen, J. K., (1973). The suppression of rejection of Nippostrongylus brasiliensis in Lewis strain rats treated with ovine prolactin. The site of the immunological defect. Immunology 24, 551–8.Google ScholarPubMed
Ogilvie, B. M., & Jones, V. E., (1971). Nippostrongylus brasiliensis in the rat: A review of immunity and the host/parasite relationship. Experimental Parasitology 29, 138–77.CrossRefGoogle Scholar
Sokal, R. R., & Rohlf, F. J., (1969). Biometry. San Francisco: W. H. Freeman & Co.Google Scholar
Spindler, L. A., (1958). The occurrence of the intestinal threadworms, Strongyloides ratti, in the tissues of rats, following experimental percutaneous infection. Proceedings of the Helminthological Society of Washington 25, 106–11.Google Scholar
Wertheim, G., & Lengy, J., (1965). Growth and development of Strongyloides ratti Sandground, 1925, in the albino rat. Journal of Parasitology 51, 636–9.CrossRefGoogle ScholarPubMed
Wilson, P. A. G., & Dick, J. M., (1964). Culture and isolation of Nippostrongylus brasiliensis infective larvae for biochemical studies. Journal of Helminthology 38, 399–404.CrossRefGoogle ScholarPubMed
Zamirdin, M., (1974). Susceptibility to nematode infection in laboratory rodents. M.Phil. thesis, University of Edinburgh.Google Scholar
Zamirdin, M., & Wilson, P. A. G., (1974). Strongyloides ratti: relative importance of maternal sources of infection. Parasitology 69, 445–53.CrossRefGoogle ScholarPubMed