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Lerbek, a synergistic mixture of methyl benzoquate and clopidol for the prevention of chicken coccidiosis

Published online by Cambridge University Press:  06 April 2009

John F. Ryley
John F. Ryley
Affiliation:
Imperial Chemical Industries Ltd, Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire, England
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Extract

Methyl benzoquate at 20 ppm or clopidol at 250 ppm in the diet show true coccidiostatic activity in infections with Eimeria tenella in the chick. Lerbek, a synergistic mixture yielding 8·35 ppm methyl benzoquate and 100 ppm clopidol, produced a partially coccidiocidal effect; relapses following restricted periods of medication were less severe, and suppression of parasite development following delayed medication was quicker and more effective than with either component of the mixture used alone.

Type
Research Article
Information
Parasitology , Volume 70 , Issue 3 , June 1975 , pp. 377 - 384
Copyright
Copyright © Cambridge University Press 1975

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References

REFERENCES

Challey, J. R. & Jeffers, T. K. (1973). Synergism between 4-hydroxyquinoline and pyridone coecidiostats. Journal of Parasitology 59, 502–4.CrossRefGoogle Scholar
Jeffers, T. K. & Challey, J. R. (1973). Collateral sensitivity to 4-hydroxyquinolines in Eimeria acervulina strains resistant to meticlorpindol. Journal of Parasitology 59, 624–30.CrossRefGoogle ScholarPubMed
Ryley, J. F. (1967). Studies on the mode of action of quinolone and pyridone coccidiostats. Journal of Parasitology 53, 1151–60.CrossRefGoogle ScholarPubMed
Ryley, J. F. & Betts, M. J. (1973). Chemotherapy of chicken coccidiosis. In Advances in Pharmacology and Chemotherapy, vol. 10 (ed. Garattini, S., Goldin, A., Hawking, F. and Kopin, I. J.), pp. 221–93. New York and London: Academic Press.Google Scholar
Ryley, J. F. & Wilson, R. G. (1971). Studies on the mode of action of the coccidiostat robenidene. Zeitschrift für Parasitenkunde 37, 85–93.CrossRefGoogle ScholarPubMed
Ryley, J. F. & Wilson, R. G. (1975). Laboratory studies with some recent anticoccidials. Parasitology 70, 203–22.CrossRefGoogle ScholarPubMed
Wang, C. C. (1973). The mitochondria of E. tenella and the mechanism of action of quinolate coccidiostats. Federation Proceedings 32, Abst. 3231, p. 789.Google Scholar