Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-26T20:59:16.208Z Has data issue: false hasContentIssue false
  • English
  • Français

Interactions between chemotherapy and immunity in bovine theileriosis

Published online by Cambridge University Press:  06 April 2009

F. E. G. Cox
F. E. G. Cox
Affiliation:
Division of Life Sciences, King's College London, Campden Hill Road, London W8 7AH
Get access Rights & Permissions [Opens in a new window]

Summary

In bovine theileriosis the use of chemotherapy to control an infection sufficiently long to permit the establishment of a solid protective immune response has been developed as a routine vaccination procedure. Infections with Theileria parva and T. annulata can be prevented by the administration of carefully controlled numbers of sporozoites simultaneously with a long acting tetracycline and this form of immunization has been widely used for the control of East Coast fever in Africa with considerable success. In this review, the nature of the chemotherapy, the immune response and the interactions between chemotherapy and immunity in the development of infection-and-treatment immunization procedures are discussed.

Keywords

Theileria parvaTheileria annulataEast Coast feverchemoimmunoprophylaxis
Type
Research Article
Information
Parasitology , Volume 105 , Issue S1: Chemotherapy and the immune system , January 1992 , pp. S79 - S84
Copyright
Copyright © Cambridge University Press 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Bansal, G. C. & Sharma, S.P. (1986). Efficacy of parvaquone and long-acting tetracycline in Theileria annulata infection. Veterinary Parasitology 21, 145–9.CrossRefGoogle ScholarPubMed
Brocklesby, D. W. & Bailey, K. P. (1962). Oxytetracycline hydrochloride in East Coast fever (Theileria parva infection). British Veterinary Journal 118, 81–5.CrossRefGoogle Scholar
Brown, C. G. D., Radley, D. E., Burridge, M. J. & Cunningham, M. P. (1977). The use of tetracyclines in the chemotherapy of experimental East Coast fever (Theileria parva infection of cattle). Tropenmedizin und Parasitologie 28, 513–20.Google ScholarPubMed
Cox, F. E. G. & Liew, F. Y. (1992). T cell subsets and cytokines in parasitic infections. Parasitology Today, 8, 371–4.CrossRefGoogle ScholarPubMed
Cunningham, M. P., Brown, C. G. D., Burridge, M. J. & Purnell, R. E. (1973). Cryopreservation of infective particles of Theileria parva. International Journal for Parasitology 3, 583–7.Google Scholar
Devos, A. J. & Roos, J. A. (1983). Chemotherapy of Theileria parva lawrencei in cattle with halofuginone. Onderstepoort Journal of Veterinary Research 50, 33–5.Google Scholar
Dhar, S., Malhotra, D. V., Bhushan, C. & Gautam, O. P. (1986). Chemotherapy of Theileria annulata infection with buparvaquone. Veterinary Record 119, 635–6.Google ScholarPubMed
Dolan, T. T. (1986). Chemotherapy of East Coast fever: The long-term weight changes, carrier state and disease manifestations of parvaquone treated cattle. Journal of Comparative Pathology 96, 137–45.CrossRefGoogle ScholarPubMed
Dolan, T. T. (Ed.) (1989). Theileriosis in Eastern, Central and Southern Africa. Nairobi: International Laboratory for Research on Animal Diseases.Google Scholar
Dolan, T. T., Teale, A. J., Stagg, D. A., Kemp, S. J., Cowan, K. N., Young, A. S., Leitch, B. L., Spooner, R. L. & Brown, C. G. D. (1984a). Histocompatibility barrier to immunization against East Coast fever using Theileria parva infected lymphoblastoid cell lines. Parasite Immunology 6, 243–50.CrossRefGoogle ScholarPubMed
Dolan, T. T., Young, A. S., Leitch, B. L. & Stagg, D. A. (1984 b). Chemotherapy of East Coast fever: Parvaquone treatment of clinical disease induced by isolates of Theileria. Veterinary Parasitology 15, 103–16.CrossRefGoogle ScholarPubMed
Dolan, T. T., Young, A. S., Losos, G. J., Mcmillan, I., Minder, C. E. & Soulsby, K. (1984 c). Dose dependent responses of cattle to Theileria parva stabilate infection. International Journal for Parasitology 14, 89–95.CrossRefGoogle Scholar
Dolan, T. T., Linyonyi, A., Mchardy, N., Bond, A. L. & Clampitt, R. B. (1988). Chemotherapy of East Coast fever: Parvaquone treatment of Theileria parva at intervals after infection. Research in Veterinary Science 44, 15–20.CrossRefGoogle ScholarPubMed
Emery, D. L., Eugui, E. M., Nelson, R. T. & Tenywa, T. (1981). Cell-mediated immune responses to Theileria parva (East Coast fever) during immunization and lethal infection in cattle. Immunology 43, 323–36.Google Scholar
Emery, D. L., Tenywa, T. & Jack, R. M. (1981). Characterization of the effector cell that mediates cytotoxicity against Theileria parva (East Coast fever) in immune cattle. Infection and Immunity 32, 1301–4.CrossRefGoogle ScholarPubMed
Eugui, E. N. & Emery, D. L. (1981). Genetically restricted cell-mediated cytotoxicity in cattle immune to Theileria parva (East Coast fever). Nature 290, 251–4.CrossRefGoogle Scholar
Gill, B. S., Bhattacharyulu, Y., Kaur, D. & Singh, A. (1976). Vaccination against bovine tropical theileriosis (Theileria annulata). Nature 264, 355–6.Google Scholar
Gill, B. S., Bhattacharyulu, Y., Singh, A., Kaur, D. & Gill, H. S. (1981). Chemotherapy against Theileria annulata. In Advances in the Control of Theileriosis, (ed. Irvin, A. D., Cunningham, M. P. & Young, A. S.), pp. 218–222. The Hague: Martinus Nijhoff.CrossRefGoogle Scholar
Hall, F. R. (1988). Antigens and immunity in Theileria annulata. Parasitology Today 4, 257–61.CrossRefGoogle ScholarPubMed
Hashemi-Fesharki, R. (1988). Control of Theileria annulata in Iran. Parasitology Today 4, 36–40.Google Scholar
Innes, E. A., Brown, C. G. D. & Spooner, R. L. (1992). Comparative immunobiology of Theileria annulata and Theileria parva. AgBiotech News and Information 4, 193N–9N.Google Scholar
Koch, R. (1903 a). Interim Report on Rhodesian Redwater or “African Coast Fever”. Salisbury: Argus Printing and Publishing Co. Ltd.Google Scholar
Koch, R. (1903b). Second Report on Rhodesian Redwater or “African Coast Fever”. Salisbury: Argus Printing and Publishing Co. Ltd.Google Scholar
Kumar, A., Sarup, S., Sharma, R. D., Nichani, A. K. & Goel, P. (1990). Chemoimmunoprophylaxis with buparvaquone against Theileria annulata infection in bovine calves. Journal of Veterinary Parasitology 4, 27–9.Google Scholar
Mchardy, N. (1979). Experimental therapy of theileriosis. Journal of the South African Veterinary Association 50, 321–2.Google Scholar
Mchardy, N. (1984). Recent advances in the chemotherapy of theileriosis. Preventive Veterinary Medicine, 2, 179–92.CrossRefGoogle Scholar
Mchardy, N. (1990). Butalex (buparvaquone) — a new therapeutic for theileriosis. In First Asian Congress of Veterinary Parasitology, pp. 31–8. Patna: Indian Association for Advancement of Veterinary Parasitology.Google Scholar
Mchardy, N., Haigh, A. J. & Dolan, T. T. (1976). Chemotherapy of Theileria parva infection. Nature 261, 698–9.Google Scholar
Mchardy, N., Hudson, A. T., Morgan, D. W. T., Rae, D. G. & Dolan, T. T. (1983). Activity of 10 naphthoquinones including parvaquone (993C) and menoctone in cattle artificially infected with Theileria parva. Research in Veterinary Science 35, 347–52.CrossRefGoogle ScholarPubMed
Mchardy, N., Wekesa, L. S., Hudson, A. T. & Randall, A. W. (1985). Antitheilerial activity of BW 720C (buparvaquone): A comparison with parvaquone. Research in Veterinary Science 39, 29–33.CrossRefGoogle ScholarPubMed
Mehlhorn, H., Moltmann, U., Schein, E. & Voigt, W. P. (1981). Electron microscopical study of the effects of halofuginone on Theileria parva. Tropenmedizin und Parasitologie 32, 231–3.Google ScholarPubMed
Mbwambo, H. A., Mkonyi, P. A., Sondi, J. & Lekaki, K. A. (1986). Chemotherapy of field cases of East Coast fever using halofuginone lactate. Acta Tropica 43, 401–6.Google ScholarPubMed
Morrison, W. I., Goddeeris, B. M., Teale, A. J., Groocock, C. M., Kemp, S. J. & Stagg, D. A. (1987). Cytotoxic T cells elicited in cattle challenged with Theileria parva (Muguga): Evidence for restriction by class I MHC determinants and parasite strain specificity. Parasite Immunology 9, 563–78.CrossRefGoogle ScholarPubMed
Musisi, F. L. (1990). Methods currently used for the control of East Coast fever: their validity and proposals for future control strategies. Parassitologia 32, 15–22.Google ScholarPubMed
Mutugi, J. J., Young, A. S., Maritim, A. C., Ndungu, S. G., Mining, S. K., Linyonyi, P. N., Ngumi, P. N., Leitch, B. L., Morzarai, S. P. & Dolan, T. T. (1989). Immunisation of cattle against theileriosis in Coast Province, Kenya: Laboratory evaluation of a Theileria parva stabilate for use in ‘infection and treatment’ immunisation in the field. Research in Veterinary Science 47, 170–7.CrossRefGoogle ScholarPubMed
Neitz, W. O. (1953). Aureomycin in Theileria parva infection. Nature 171, 34–5.CrossRefGoogle ScholarPubMed
Neitz, W. O. (1957). Theileriosis, gonderioses and cytauxozoonoses: A review. Onderstepoort Journal of Veterinary Research 27, 275–430.Google Scholar
Ngumi, P. N., Young, A. S., Lampard, D., Mining, S. K., Ndungu, S. G., Lesan, A. C., Williamson, S. M., Linyonyi, A. & Kariuki, D. P. (1992). Further evaluation of the use of buparvaquone in the infection and treatment method of immunising cattle against Theileria parva derived from African buffalo (Syncerus caffer). Veterinary Parasitology 43, 15–24.CrossRefGoogle ScholarPubMed
Norval, R. A. I., Perry, B. D. & Young, A. S. (1992). The Epidemiology of Theileriosis in Africa. London: Academic Press.Google Scholar
Pipano, E. (1981). Schizonts and tick stages in immunisation against Theileria annulata infection. In Advances in the Control of Theileriosis, (ed. Irvin, A. D., Cunningham, M. P. & Young, A. S.), pp. 242–52. The Hague: Martinus Nijhoff.CrossRefGoogle Scholar
Pitman-Moore Ltd. (1990). Butalex Injection: the Treatment for Theileriosis. Harefield: Pitman-Moore Limited.Google Scholar
Potgieter, F. T., Stoltsz, W. H., Blouin, E. F. & Roos, J. A. (1988). Corridor disease in South Africa: A review of the current status. Journal of the South African Veterinary Association 59, 155–60.Google ScholarPubMed
Preston, P. M., Brown, C. G. D. & Richardson, W. (1992). Cytokines inhibit the development of trophozoite-infected cells of Theileria annulata and Theileria parva but enhance the proliferation of macroschizont-infected cell lines. Parasite Immunology 14, 125–41.CrossRefGoogle ScholarPubMed
Radley, D. E. (1981). Infection and treatment immunization against theileriosis. In Advances in the Control of Theileriosis, (ed. Irvin, A. D., Cunningham, M. P. & Young, A. S.), pp. 227–36. The Hague: Martinus Nijhoff.CrossRefGoogle Scholar
Schein, E. & Voigt, W. P. (1979). Chemotherapy of bovine theileriosis with halofuginone. Acta Tropica 36, 391–4.Google Scholar
Schein, E. & Voigt, W. P. (1981). Chemotherapy of theileriosis in cattle. In Advances in the Control of Theileriosis, (ed. Irvin, A. D., Cunningham, M. P. & Young, A. S.), pp. 212–14. The Hague: Martinus Nijhoff.Google Scholar
Sergent, E., Donatien, A. L., Parrot, L. M., Lestoquard, F. & Plantureu, E. (1927). Les piroplasmoses bovine d' Algérie: Deuxieme mémoire. Methods de premunition. Archives de l' Institute Pasteur d' Algérie 5, 245–468.Google Scholar
Spooner, P. R. (1990). The effects of oxytetracycline on Theileria parva in vitro. Parasitology 100, 11–17.CrossRefGoogle ScholarPubMed
Spreull, J. (1914). East Coast fever inoculation in the Transkeian Territories, South Africa. Journal of Comparative Pathology and Therapeutics 27, 299–304.CrossRefGoogle Scholar
Subramanian, G., Srivastava, R. V. N., Bansal, G. C. & Ray, D. (1988). A field trial with live schizont vaccine for control of bovine theileriosis. Indian Journal of Animal Sciences 58, 635–9.Google Scholar
Theiler, A. (1911). Progress report on the possibility of vaccinating cattle against East Coast fever. In First Report of the Director of Veterinary Research, Union of South Africa, Department of Agriculture, pp. 47–207. Pretoria: Government Printing and Stationery Office.Google Scholar
Uilenberg, G., Silayo, R. S., Mpangala, C. & Tondeur, W. (1977). Studies on Theileridae (Sporozoa) in Tanzania. 10. A large-scale field trial of immunization against cattle theileriosis. Tropenmedizin und Parasitologie 28, 449–506.Google Scholar
Walker, J. (1926). Observations on the nature of immunity conferred to East Coast fever by natural infection, or exposure thereto, inoculated and non-inoculated cattle. South African Journal of Science 23, 723–5.Google Scholar
Wilde, J. K. H. (1967). East Coast fever. Advances in Veterinary Science 11, 207–59.Google Scholar
Wilde, J. K. H., Brown, C. G. D., Hulliger, L., Gall, D. & Macleod, W. G. (1968). East Coast fever: Experiments with tissues of infected ticks. British Veterinary Journal 124, 196–208.Google Scholar
Young, A. S., Mutugi, J. J., Maritim, A. C. & Linyonyi, A. (1990). Problems associated with the use of drugs and safety in infection and treatment immunization. In Progress Towards the Control of East Coast Fever (Theileriosis) in Kenya, (ed. Young, A. S., Mutugi, J. J. & Maritim, A. C.). pp. 30–9. Nairobi: Kenya Agricultural Research Institute.Google Scholar
Young, A. S., Mutugi, J. J., Kariuki, D. P., Lampard, D., Maritim, A. C., Ngumi, P. N., Linyonyi, A., Leitch, B. L., Ndungu, S. G., Lesan, A. C., Mining, S. K., Grootenhuis, J. G., Orinda, G. O. & Wesonga, D. (1992). Immunisation of cattle against theileriosis in Nakuru District of Kenya by infection and treatment and the introduction of unconventional tick control. Veterinary Parasitology 42, 225–40.Google Scholar