Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-24T11:29:46.122Z Has data issue: false hasContentIssue false
  • English
  • Français

Failure to produce resistance to chloroquine in Plasmodium gallinaceum in chicks

Published online by Cambridge University Press:  06 April 2009

Ann Bishop  and
Elspeth W. McConnachie
Ann Bishop
Affiliation:
From the Molteno Institute, University of Cambridge
Elspeth W. McConnachie
Affiliation:
From the Molteno Institute, University of Cambridge
Get access Rights & Permissions [Opens in a new window]

Extract

A strain of Plasmodium gallinaceum has been treated for 16 months with chloroquine, under conditions which previously have produced strains resistant to proguanil, sulphonamides and pamaquin, but no change in reaction to the drug has occurred.

Type
Research Article
Information
Parasitology , Volume 42 , Issue 1-2 , March 1952 , pp. 52 - 56
Copyright
Copyright © Cambridge University Press 1952

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Adams, A. R. D. & Seaton, D. R. (1949). Resistance to paludrine developed by a strain of Plasmodium falciparum. Trans. R. Soc. trop. Med. Hyg. 42, 314.Google Scholar
Berliner, W. R., Earle, V. P., Taggart, J. V., Zubrod, C. G., Welch, W. J., Conan, N. J., Bauman, E., Scudder, S. T. & Shannon, J. A. (1948). Studies on the chemotherapy of the human malarias. VI. Physiological disposition, antimalarial activity, and toxicity of several derivatives of 4-aminoquinoline. J. Clin. Invest. 27, 98.Google Scholar
Bishop, A. & Birkett, B. (1947). Acquired resistance to paludrine in Plasmodium gallinaceum. Acquired resistance and persistence after passage through the mosquito. Nature, Lond., 159, 884.CrossRefGoogle Scholar
Bishop, A. & Birkett, B. (1948). Drug-resistance in Plasmodium gallinaceum, and the persistence of paludrine-resistance after mosquito transmission. Parasitology, 39, 125.Google Scholar
Bishop, A. & McConnachie, E. W. (1950). Sulpha-diazine-resistance in Plasmodium gallinaceum and its relation to other antimalarial compounds. Parasitology, 40, 163.Google Scholar
Black, R. H. (1946). The effect of antimalarial drugs on Plasmodium falciparum (New Guinea strains) developing in vitro. Trans. R. Soc. trop. Med. Hyg. 40, 163.CrossRefGoogle ScholarPubMed
Blanchard, K. C. (1947). Antimalarial drugs. Ann. Rev. Biochem. 16, 587.CrossRefGoogle ScholarPubMed
Cooper, W. C., Coatney, G. R. & Imboden, C. A. (1950). Studies in human malaria. XXIII. Acquired resistance to chlorguanide in the Chesson strain of Plasmodium vivax. Nat. Malaria Soc. 9, 59.Google Scholar
Edeson, J. F. B. & Field, J. W. (1950). Proguanil-resistant falciparum malaria in Malaya. Brit. Med. J. 1, 147.Google Scholar
Findlay, G. M. (1951). Recent Advances in Chemotherapy, 2. London: J. and A. Churchill Ltd.Google Scholar
Van Goor, W. T. & Lodens, J. G. (1950). Clinical malaria prophylaxis with proguanil. Documenta Neer-landica et Indonesica de Morbis Tropicis, 2, 62.Google Scholar
Hawking, F. & Perry, W. L. M. (1948). Resistance to proguanil (paludrine) in a mammalian malaria parasite. Lancet, 2, 850.CrossRefGoogle Scholar
Knoppers, A. T. (1947). Acquired resistance (twofold) to quinine in Plasmodium gallinaceum. Nature, Lond., 160, 606.Google Scholar
Loeb, R. F. et al. (1946). Activity of a new antimalarial agent, chloroquine (SN 7618). J. Amer. Med. Ass. 130, 1069.CrossRefGoogle Scholar
Lourie, E. M. & Seaton, D. R. (1949). Resistance to paludrine developed by a strain of Plasmodium vivax. Trans. R. Soc. trop. Med. Hyg. 42, 315.Google Scholar
McConnachie, E. W. (1951). Latent infections in avian malaria in relation to the production of drug resistance. Parasitology 41, 110.CrossRefGoogle Scholar
Pullman, T. N., Craige, B., Alving, A. S., Whorton, C. M., Jones, R. & Eichelberger, L. (1948). Comparison of chloroquine, quinacrine (atabrine), and quinine in the treatment of acute attacks of sporo-zoite-induced uivax malaria (Chesson strain). J. Clin. Invest. 27, 46.Google Scholar
Rollo, I. M., Williamson, J. & Lourie, E. M. (1948). Acquired paludrine-resistance in Plasmodium gallinaceum. II. Failure to produce such resistance by prolonged treatment of latent infections. Ann. trop. Med. Parasit. 42, 241.CrossRefGoogle Scholar
Schmidt, L. H., Genther, C. S., Fradkin, R. & Squires, W. (1949). Development of resistance to chlorguanide (paludrine) during treatment of infections with Plasmodium cynomolgi. J. Pharmacol. 95, 382.Google ScholarPubMed
Thompson, P. E. (1948). On the ability of Plasmodium lophurae to acquire resistance to chlorguanide, camoquin and chloroquine. J. Infect. Dis. 83, 250.Google Scholar
Williamson, J. & Lourie, E. M. (1947). Acquired paludrine-resistance in Plasmodium gallinaceum. I. Development of resistance to paludrine and failure to develop resistance to certain other antimalarials. Ann. trop. Med. Parasit. 41, 278.CrossRefGoogle ScholarPubMed
Williamson, J., Bertram, D. S. & Lourie, E. M. (1947). Acquired resistance to paludrine in Plasmodium gallinaceum. Nature, Lond., 159, 885.Google Scholar