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Experimental studies of age-prevalence curves for Schistosoma mansoni infections in populations of Biomphalaria glabrata

Published online by Cambridge University Press:  06 April 2009

R. M. Anderson  and
Jenny Crombie
R. M. Anderson
Affiliation:
Department of Pure and Applied Biology, Imperial College, London University, London SW7 2A7
Jenny Crombie
Affiliation:
Department of Pure and Applied Biology, Imperial College, London University, London SW7 2A7
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Summary

We report the results of experimental studies of the generation of age-prevalence curves for Schistosoma mansoni infections in laboratory populations of Biomphalaria glabrata. Within snail populations of varying sizes and age structures, the net force of infection is shown to be linearly dependent on the rate at which miracidia are introduced into the aquatic habitat of the host. For individual snails, the per capita force of infection is shown to be related to snail age and size, and the death rate of shedding snails is demonstrated to be dependent on the period of time during which a snail has been releasing cercariae. Both factors are important determinants of the proportion of infected snails within populations of hosts and may generate convex age-prevalence curves. Comparisons of snail abundance in populations either exposed, or not exposed, to infection suggest that S. mansoni can act to significantly depress the population growth of its intermediate host. Mathematical models are developed, encorporating the age structure of snail populations, to aid in the interpretation of experimental results.

Type
Research Article
Information
Parasitology , Volume 89 , Issue 1 , August 1984 , pp. 79 - 106
Copyright
Copyright © Cambridge University Press 1984

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References

Anderson, R. M. (ed.) (1982). Population Dynamics of Infectious Diseases: Theory and Applications. London: Chapman & Hall.Google Scholar
Anderson, R. M. (1982). Population Dynamics of Infectious Diseases: Theory and Applications. London: Chapman & Hall.Google Scholar
Anderson, R. M. & May, R. M. (1979). Prevalence of schistosome infections within molluscan populations: observed patterns and theoretical predictions. Parasitology 79, 63–94.CrossRefGoogle ScholarPubMed
Anderson, R. M., Mercer, J. G., Wilson, R. A. & Carter, N. P. (1982). Transmission of Schistosoma mansoni from man to snail: experimental studies of miracidial survival and infectivity in relation to larval age, water temperature, host size and age. Parasitology 85, 339–60.CrossRefGoogle Scholar
Barbour, A. D. (1978). Macdonald's Model and the transmission of bilharzia. Transactions of the Royal Society of Tropical Medicine and Hygiene 72, 6–15.CrossRefGoogle ScholarPubMed
Barbosa, E. S. & Olivier, L. (1958). Studies on the snail vectors of bilharziasis mansoni in north-eastern Brazil. Bulletin of the World Health Organization 18, 895.Google ScholarPubMed
Berrie, A. D. (1970). Snail Problems in African schistosomiasis. Advances in Parasitology vol. 8, (ed. Dawes, B.), pp. 43–96. London: Academic Press.Google Scholar
Carter, N. P., Anderson, R. M. & Wilson, R. A. (1982). Transmission of Schistosoma mansoni from man to snail: laboratory studies on the influence of snail and miracidial densities on transmission success. Parasitology 85, 361–72.CrossRefGoogle Scholar
Chernin, E. (1972). Penetrative activity of Schistosoma mansoni miracidia stimulated by exposure to snail conditioned water. Journal of Parasitology 58, 209–12.CrossRefGoogle ScholarPubMed
Chu, K. Y., Massoud, J. & Sabbaghian, H. (1966 a). Host-parasite relationship of Bulinus truncatus and Schistosoma haematobium in Iran. I. Effect of the age of B. truncatus on the development of S. haematobium. Bulletin of the World Health Organization 34, 113–19.Google ScholarPubMed
Chu, K. Y., Sabbaghian, H. & Massoud, J. (1966 b). Host-parasite relationship of Bulinus truncatus and Schistosoma haematobium in Iran. 2. Effect of exposure dosage of miracidia on the biology of the snail host and the development of the parasites. Bulletin of the World Health Organization 34, 131–3.Google ScholarPubMed
Cohen, J. E. (1973). Selective host mortality in a catalytic model applied to schistosomiasis. American Naturalist 107, 199–212.CrossRefGoogle Scholar
De Witt, W. B. (1955). Influence of temperature on penetration of snail hosts by S. mansoni miracidia. Experimental Parasitology 4, 271–6.CrossRefGoogle Scholar
Evans, A. S. & Stirewalt, M. A. (1951). Variations in infectivity of cercariae of Schistosoma mansoni. Experimental Parasitology 1, 19–22.CrossRefGoogle Scholar
von Foerster, H. (1959). Some remarks on changing populations. In Kinetics of Cellular Proliferation (ed. Stohlman, F.) pp. 382–407. New York: Grune and Stratton.Google Scholar
Hairston, N. G. (1965). An analysis of age-prevalence data by catalytic models. A contribution to the study of bilharziasis. Bulletin of the World Health Organization 33, 163–75.Google Scholar
Lackie, A. M. (1980). Invertebrate immunity. Parasitology 80, 393–412.CrossRefGoogle ScholarPubMed
Mason, P. R. (1977). Stimulation of the activity of Schistosoma mansoni miracidia by snail-conditioned water. Parasitology 75, 325–38.CrossRefGoogle ScholarPubMed
May, R. M. (1977). Togetherness among schistosomes: its effects on the dynamics of the infection. Mathematical Biosciences 35, 301–43.CrossRefGoogle Scholar
Minchella, D. H. & Loverde, P. T. (1983). Laboratory comparison of the relative successes of Biomphalaria glabrata stocks which are susceptible and insusceptible to infection with Schistosoma mansoni. Parasitology 86, 335–44.CrossRefGoogle ScholarPubMed
Muench, H. (1959). Catalytic Models in Epidemiology. Cambridge, Massachusetts: Harvard University Press.CrossRefGoogle Scholar
Pan, C. T. (1965). Studies on the host-parasite relationship between Schistosoma mansoni and the snail Australorbis glabratus. American Journal of Tropical Medicine and Hygiene 14, 931–76.CrossRefGoogle ScholarPubMed
Pesignan, T. P., Hairston, N. G., Jauregui, J. J., Garcia, E. G., Santos, A. T., Santos, B. C. & Besa, A. A. (1958). Studies on Schistosoma japonicum infection in the Philippines. 2. The molluscan host. Bulletin of the World Health Organization 18, 481–578.Google Scholar
Prah, S. K. & James, C. (1977). The influence of physical factors on the survival and infectivity of miracidia of Schistosoma mansoni and S. haematobium. I. Effect of temperature and ultra-violet light. Journal of Helminthology 51, 73–85.CrossRefGoogle ScholarPubMed
Shiff, C. J. (1974). Seasonal factors influencing the location of Bulinus (Physopsis) globosus by miracidia of Schistosoma haematobium in nature. Journal of Parasitology 60, 578–83.CrossRefGoogle ScholarPubMed
Standen, O. D. (1952). Experimental infection of Australorbis glabratus with Schistosoma mansoni. I. Individual and mass infection of snails, and the relationship to temperature and season. Annals of Tropical Medicine and Parasitology 46, 48–53.CrossRefGoogle ScholarPubMed
Sturrock, R. F. (1973). Field studies on the transmission of Schistosoma mansoni and on the bionomics of its intermediate host, Biomphalaria glabrata, on St Lucia, West Indies. International Journal for Parasitology 3, 175–94.CrossRefGoogle Scholar
Sturrock, R. F., Cohen, J. E. & Webbe, G. (1975). Catalytic curve analysis of schistosomiasis in snails. Annals of Tropical Medicine and Parasitology 69, 133–4.CrossRefGoogle ScholarPubMed
Sturrock, R. F. & Webbe, G. (1971). The application of catalytic models to schistosomiasis in snails. Journal of Helminthology 45, 189–200.CrossRefGoogle ScholarPubMed
Sturrock, R. F. & Upatham, E. S. (1973). An investigation of the interactions of some factors influencing the infectivity of Schistosoma mansoni miracidia to Biomphalaria glabrata. International Journal for Parasitology 3, 35–41.CrossRefGoogle ScholarPubMed
Webbe, G. (1962). The transmission of Schistosoma haematobium in an area of Lake Province, Tanganyika. Bulletin of the World Health Organization 27, 59–85.Google Scholar
Upatham, E. S. (1972). Effect of water depth on the infection of Biomphalaria glabrata by miracidia of St Lucian Schistosoma mansoni under laboratory and field conditions. Journal of Helminthology XLVI, 317–25.CrossRefGoogle Scholar