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Eimeria falciformis (Eimer, 1870) in specific pathogen free and gnotobiotic mice

Published online by Cambridge University Press:  06 April 2009

Dawn Owen
Dawn Owen
Affiliation:
Medical Research Council Laboratory Animals Centre, Woodmansterne Road, Carshalton, Surrey SM5 4EF
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Extract

The endogenous and exogenous stages of a species of murine Eimeria were examined and compared with descriptions of other species isolated from Mus musculus. Developing stages of the parasite were found in the epithelial cells of the caecum and colon. Three asexual generations were observed, the third becoming apparent on the fourth day concurrently with gametogeny. The total length of the prepatent period was 5 days. Oocysts of the coccidian, identified as Eimeria falciformis, were administered to a group of germfree mice. Despite a dose level of 1 ü 106, the coccidium was not established. Histological examination indicated the failure of the sporozoite to penetrate its host epithelium. The possible causes of this phenomenon were discussed.

Type
Research Article
Information
Parasitology , Volume 71 , Issue 2 , October 1975 , pp. 293 - 303
Copyright
Copyright © Cambridge University Press 1975

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References

Abrams, G. D., Bauer, H. & Sprinz, H. (1963). Influence of the normal flora on mucosal morphology and cellular renewal in the ileum. A comparison of germfree and conventional mice. Laboratory Investigation 12, 355–64.Google ScholarPubMed
Blackmore, D. K. & Hill, A. (1972). The isolation and identification of bacteria and mycoplasma pathogenic to laboratory animals. In Safety in Microbiology (ed. Shapton, D. A. and Board, R. G.). London and New York: Academic Press.Google Scholar
Černá, Z. (1962). Contribution to the knowledge of coccidia parasitic in Muridae. Vestnik Ceskoslovenske Spolecnosti Zoologike 26, 1–13.Google Scholar
Černá, Z. & Senaud, J. (1969). Eimeria pragnensis sp. nova. A new coccidian parasite from the intestine of mice. Folia Parasitologia 16, 171–5.Google Scholar
Clark, D. T., Smith, C. K. & Dardas, R. B. (1962). Pathological and immunological changes in gnotobiotic chickens due to Eimeria tenella. Poultry Science 41, 1635–6 (Abstract).Google Scholar
Coates, N. E., Gordon, H. A. & Wostmann, B. S. (1968). In The Germfree Animal in Research. London and New York: Academic Press.Google Scholar
Cordero del Campillo, C. (1959). Estudios sobre Eimeria falciformis (Eimer, 1870) parásito del ratón I, observaciones sobre el periodo prepatente, esporulacion, morfologia de los ooquistes y estudio biometrico de los mismos, produccion de ooquistes y patogenicidad. Revista Iberica de Parasitologia 19, 351–68.Google Scholar
Desplaces, A., Zagury, D. & Sacquet, E. (1963). Étude de la fonction thyroidienne du Rat privé de Bactéries (germfree). Comptes Rendus Hebdomadaires des Séances de l' Académie des Sciences, Paris, 257, 756–8.Google Scholar
Eimer, T. (1870). Uber die ei- oder kugelformigen sogenannten Psorospermien der Wirbelthiere. Wurzburg., A. Studers, 58 pp.Google Scholar
Ernst, J. V., Chobotar, B. & Hammond, D. M. (1971). The oocysts of Eimeria vermiformis sp. n. and E. papillata sp. n. (Protozoa: Eimeriidae) from the mouse Mus musculus, Protozoology 18, 221–3.Google Scholar
Haberkorn, A. (1970). Die Entwicklung von Eimeria falciformis (Eimer 1870) in der weissen Maus (Mus musculus). Zeitschrift fur Parasitenkunde 34, 49–69.CrossRefGoogle Scholar
Hedge, K. S., Reid, W. M., Johnson, J. & Womack, H. E. (1969). Pathogenicity of Eimeria brunetti in bacteria free and conventional chickens. Journal of Parasitology 55, 402–5.Google Scholar
Johnson, J., Reid, W. M. & Kemp, R. L. (1972). The development of Eimeria tenella in germfree chicks. In The IVth International Symposium of Germ Free Research, New Orleans, Louisiana, U.S.A.Google Scholar
Levine, N. D., Bray, R. S., Ivens, V. & Gunders, A. E. (1959). On the parasitic protozoa of Liberia. V. Coccidia of Liberian rodents. Journal of Protozoology 6, 215–22.CrossRefGoogle Scholar
Levine, N. D. & Ivens, V. (1965). The coccidian parasites (Protozoa: Sporozoa) of rodents. III. Biological Monographs 33, 1–365.Google Scholar
Musaev, M. A. & Veisov, A. M. (1965). Coccidia of Rodents of the USSR, 154 pp. Akademii Nauk, Azerbaijan, SSR. Baku.Google Scholar
Pellérdy, L. P. (1965). Coccidia and Coccidiosis. Budapest: Akedémiai Kiadó.Google Scholar
Reichenow, E. (1921). Die Coccidien. In Pronouzek Handbuck der pathogenen Protozoen, Leipzig, pp. 1136–277.Google Scholar
Reimer, O. (1923). Zur Pathologie der Mause kokzidiose. Diss Tierarztliche, Hochschule Berlin.Google Scholar
Todd, K. S. Jr., & Lepp, D. L. (1971). The life cycle of Eimeria vermiformis (Ernst, Chobotar and Hammond 1971) in the mouse Mus musculus. Journal of Protozoology 18, 332–7.CrossRefGoogle ScholarPubMed
Townsend, G. (1969). The grading of commercially bred laboratory animals. Veterinary Record 225–6.CrossRefGoogle ScholarPubMed
Visco, R. J. & Burns, W. C. (1972 a). Eimeria tenella in bacteria free and conventionalised chicks. Journal of Parasitology 58, 323–31.CrossRefGoogle Scholar
Visco, R. J. & Burns, W. C. (1972 b). Eimeria tenella in bacteria free chicks of relatively susceptible strains. Journal of Parasitology 58, 586–8.CrossRefGoogle ScholarPubMed
Weinstein, P. P., Newton, W. I., Sawyer, T. K. & Sommerville, R. (1969). Nematospiroides dubius: development and passage in the germfree mouse and a comparative study of the free living stages in germfree faeces and conventional cultures. Transactions of the American Microscopical Society 88, 95–117.CrossRefGoogle Scholar
Wostmann, B. S. & Bruckner-Kardoss, E. (1966). Oxidation-reduction potentials in caecal contents of germfree and conventional rats. Proceedings of the Society for Experimental Biology and Medicine 121, 1111.CrossRefGoogle ScholarPubMed
Yakimoff, W. L. & Gousseff, W. F. (1938). The coccidia of mice (Mus musculus). Parasitology 30, 1–4.CrossRefGoogle Scholar