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The effect of host lactation on the self-cure of Nippostrongylus brasiliensis in rats

Published online by Cambridge University Press:  06 April 2009

R. M. Connan
R. M. Connan
Affiliation:
Department of Animal Pathology, Madingley Road, Cambridge
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Extract

The primary infection of breeding female rates with N. brasiliensis was examined as an experimental model for the study of the effect of lactation on host-parasite relationships.

Self-cure was inhibited when the period of infection corresponded with lactation, and a majority of worms could persist to day 34 when lactation was prolonged. A normal self-cure occurred during pregnancy, when litters were removed at birth or when the suckling litter was reduced to 3 young.

Type
Research Article
Information
Parasitology , Volume 61 , Issue 1 , August 1970 , pp. 27 - 33
Copyright
Copyright © Cambridge University Press 1970

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References

REFERENCES

Bakarat, M. R. (1951). A new procedure for the cultivation of the nematode parasites. Journal of the Egyptian Medical Association 34, 323–6.Google Scholar
Barth, E. E. E., Jarrett, W. F. H. & Urquhart, G. M. (1966). Studies on the mechanism of the self-cure reaction in rats infected with Nippostrongylus brasiliensis. Immunology 10, 459–64.Google Scholar
Bintarningsih, , Lyons, W. R., Johnson, R. E. & Li, C. H. (1958). Hormonally induced lactation in hypophysectomized rats. Endocrinology 63, 540–8.CrossRefGoogle ScholarPubMed
Connan, R. M. (1968). Studies on the worm populations in the alimentary tract of breeding ewes. Journal of Helminthology 42, 9–28.CrossRefGoogle ScholarPubMed
Dunsmore, J. D. (1965). Ostertagia spp. in lambs and pregnant ewes. Journal of Helminthology 39, 159–84.CrossRefGoogle ScholarPubMed
Gibbs, H. C. (1967). Some factors involved in the ‘Spring rise’ phenomenon in sheep. In The Reaction of the Host to Parasitism; Proceedings of Third International Conference World Association for the Advancement of Veterinary Parasitology, pp. 160–73.Google Scholar
Greenwald, G. S. & Johnson, D. C. (1968). Gonadotrophic requirements for the maintenance of pregnancy in the hypophysectomized rat. Endocrinology 83, 1052–64.CrossRefGoogle Scholar
Jansen, J. Jr (1968). Some observations on the ‘Spring Rise’ in sheep. (In Dutch.) Tijdschrift voor Diergeneeskunde 93, 422–30.Google Scholar
Jarrett, E. E. E., Jarrett, W. F. H. & Urquhart, G. M. (1968). Quantitative studies on the kinetics of establishment and expulsion of intestinal nematode populations in susceptible and immune hosts. Nippostrongylus brasiliensis in the rat. Parasitology 58, 625–39.CrossRefGoogle ScholarPubMed
Jennings, F. W., Mulligan, W. & Urquhart, G. M. (1963). Variables in X-ray irradiation of Nippostrongylus brasiliensis larvae. Experimental Parasitology 13, 367–73.CrossRefGoogle Scholar
Meites, J. & Nicoll, C. S. (1959). Hormonal prolongation of lactation for 75 days after litter withdrawal in post-partum rats. Endocrinology 65, 572–9.CrossRefGoogle Scholar
Michel, J. F. (1967). Regulation of egg output of populations of Ostertagia ostertagi. Nature, London 215, 1001–2.CrossRefGoogle ScholarPubMed
Ogilvie, B. M. (1968). Immunity to Nippostrongylus brasiliensis. In Nippostrongylus and Toxoplasma. Symposium of the British Society for Parasitology 7, 31–40.Google Scholar
Oshima, T. (1961). Influence of pregnancy and lactation on migration of the larvae of Toxocara canis in mice. Journal of Parasitology 47, 657–60.CrossRefGoogle ScholarPubMed
Psychoyos, A. (1967). The hormonal interplay controlling egg-implantation in the rat. In Advances in Reproductive Physiology 2, 257–77. Anne, McLaren (ed.), London: Logos and Academic Press.Google Scholar