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The effect of a milk diet upon Plasmodium berghei, Nuttallia (=Babesia) rodhaini and Trypanosoma brucei infections in mice

Published online by Cambridge University Press:  06 April 2009

Frank Nowell
Frank Nowell
Affiliation:
Department of Zoology, University of Reading, Reading, Berks, RG 1 5AQ
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Extract

Suppression of P. berghei infections but not those of N. rodhaini or T. brucei in mice on milk diet were noted. The suppression of P. berghei was variable. This was not due to differences of the quality of the milk or to the mice eating faeces, sawdust, etc. which may be rich in PABA. The variability was at least partially due to selection of a strain of parasite probably requiring a lower level of PABA than normal. One such strain was isolated and its pattern of infection compared with the normal strain. The ‘milk diet’ strain caused a higher fatality rate in mice on milk diet but always showed a lower parasitaemia growth rate in mice on normal diet. When repassaged through mice on normal diet, the ‘milk diet’ strain did not revert immediately to the infection pattern of the normal strain.

Type
Research Article
Information
Parasitology , Volume 61 , Issue 3 , December 1970 , pp. 425 - 433
Copyright
Copyright © Cambridge University Press 1970

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