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Differences in the chemical composition and carbohydrate metabolism of Echinococcus granulosus (horse and sheep strains) and E. multilocularis

Published online by Cambridge University Press:  06 April 2009

D. P. McManus  and
J. D. Smyth
D. P. McManus
Affiliation:
Department of Zoology and Applied Entomology, Imperial College of Science and Technology, London, SW7 2BB
J. D. Smyth
Affiliation:
Department of Zoology and Applied Entomology, Imperial College of Science and Technology, London, SW7 2BB
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Summary

Metabolic studies in vitro and studies on chemical composition indicate basic biochemical differences between the horse and sheep strains of Echinococcus granulosus and between these and the closely related species, E. multilocularis. The horse strain of E. granulosus has a similar level of DNA, but significantly more polysaccharides and lipids, with less RNA and protein than the sheep strain. E. multilocularis has significantly more lipids and DNA but less polysaccharides than the horse and sheep strains of E. granulosus, more RNA and protein than the horse strain but similar protein to and less RNA than the sheep strain. Incubations under air and under 95% N2-5% CO2 for 3 h show that only E. multilocularis takes up glucose, that all three forms consume different amounts of oxygen and endogenous glycogen and produce different concentrations of lactate, succinate, acetate, malate, pyruvate, propionate and ethanol as end products of carbohydrate metabolism.

Type
Research Article
Information
Parasitology , Volume 77 , Issue 1 , August 1978 , pp. 103 - 109
Copyright
Copyright © Cambridge University Press 1978

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