Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-23T19:58:36.962Z Has data issue: false hasContentIssue false
  • English
  • Français

A basis to extend the proof of migration routes of immature parasites inside hosts: estimated time of arrival of Nippostrongylus brasiliensis and Strongyloides ratti in the gut of the rat

Published online by Cambridge University Press:  06 April 2009

N. R. Tindall  and
P. A. G. Wilson
N. R. Tindall
Affiliation:
University of Edinburgh, Department of Zoology, West Mains Road, Edinburgh EH9 3JT
P. A. G. Wilson
Affiliation:
University of Edinburgh, Department of Zoology, West Mains Road, Edinburgh EH9 3JT
Get access Rights & Permissions [Opens in a new window]

Summary

The time taken for larvae of Nippostrongylus brasiliensis and a homogonic strain of Strongyloides ratti to complete their migration from the skin surface to the small intestine of the rat was estimated by a new method in which a mirror image of arrival times was created by counting mature parasites at day 8 (N. brasiliensis) or day 5 (S. ratti) in the intestines of rats that had received a single pulse of morantel tartrate by stomach tube at different times starting 10 h after skin application of exact doses of infective larvae. It was confirmed that the effect of the drug was confined to parasites in the gut, so that the kinetics of migration were unperturbed.

Keywords

migrationproofpathwaynematodeparasite
Type
Research Article
Information
Parasitology , Volume 100 , Issue 2 , April 1990 , pp. 275 - 280
Copyright
Copyright © Cambridge University Press 1990

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Love, R J., Kelly, J. D. & Dineen, J. K. (1974). Nippostrongylus brasiliensis: Effects of immunity on the pre-intestinal and intestinal larval stages of the parasite. International Journal for Parasitology 4, 183–91.CrossRefGoogle ScholarPubMed
Murrell, K. D. (1980). Strongyloides ratti: Acquired resistance in the rat to preintestinal migrating larvae. Experimental Parasitology 50, 417–25.Google Scholar
Tindall, N. R. & Wilson, P. A. G. (1988). Criteria for a proof of migration routes of immature parasites inside hosts exemplified by studies of Strongyloides ratti in the rat. Parasitology 96, 551–63.CrossRefGoogle ScholarPubMed
Tindall, N. R. & Wilson, P. A. G. (1990 a). An extended proof of migration routes of immature parasites inside hosts: pathways of Nippostrongylus brasiliensis and Strongyloides ratti in the rat are mutually exclusive. Parasitology 100, 281–8.Google Scholar
Tindall, N. R. & Wilson, P. A. G. (1990 b). A technique for skin application of exact doses of Nippostrongylus brasiliensis to rats. Journal of Helminthology (in the Press).CrossRefGoogle ScholarPubMed
Twohy, D. W. (1956). The early migration and growth of Nippostrongylus muris in the rat. American Journal of Hygiene 63, 165–85.Google ScholarPubMed
Wilson, P. A. G. (1979). Tracking radioactive larvae of Strongyloides ratti in the host. Parasitology 79, 29–38.CrossRefGoogle ScholarPubMed
Wilson, P. A. G. (1983). Roundworm juvenile migration in mammals: the pathways of skin-penetrators reconsidered. In Aspects of Parasitology (ed.Meerovitch, E.) pp. 459–485. Montreal: Institute of Parasitology.Google Scholar
Wilson, P. A. G. & Simpson, N. E. (1981). Dynamics of infection in rats given low doses of homogonic and heterogonic Strongyloides ratti. Parasitology 83, 459–75.Google Scholar
Wilson, P. A. G., Simpson, N. E. & Seaton, D. S. (1986). The effect of method of infection on the pathway of juvenile Strongyloides ratti in the host. Journal of Helminthology 60, 79–91.CrossRefGoogle ScholarPubMed